ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft failure"

  • 2020 American Transplant Congress

    Post-Transplant Hepatic CHOP Expression Dictates Clinical Outcomes in Liver Transplantation

    H. Hirao1, T. Ito1, K. Nakamura2, S. Kageyama1, K. Kadono1, H. Kojima1, K. J. Dery1, S. Younan1, R. W. Busuttil1, F. M. Kaldas1, J. W. Kupiec‐Weglinski1

    1UCLA, Los Angeles, CA, 2Kyoto University, Kyoto, Japan

    *Purpose: Endoplasmic reticulum (ER) stress plays a pivotal role in the mechanism of liver ischemia reperfusion injury (IRI). Although we and others have demonstrated the…
  • 2020 American Transplant Congress

    Evaluating the Effect of HCV Status on the KDPI in the Era of DAA Therapy

    J. Husson1, S. Curreli2, B. Ravichandran3, E. Wilson4

    1Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, 2Institute of Human Virology, Baltimore, MD, 3University of Maryland Medical Center, University of Maryland School of Pharmacy, Baltimore, MD, 4Institue of Human Virology, University of Maryland School of Medicine, Baltimore, MD

    *Purpose: The association between KDPI and kidney graft outcomes is limited in the era of DAA therapy.*Methods: We analyzed adult renal transplants, at the University…
  • 2020 American Transplant Congress

    Changes in Gut Microbiota and Acute Rejection after Kidney Transplantation

    H. Cho1, J. Kim2, H. Kim2, J. Park3, M. Kwak4, B. Kim4, D. Kim2, J. Lee5, B. Kim6, H. Lee2

    1Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea, Republic of, 2Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, 3Department of Internal Medicine, Kangwon National University Hospital, Chuncheon, Korea, Republic of, 4ChunLab Inc. Seoul National University, Seoul, Korea, Republic of, 5Department of Internal Medicine, Seoul National University Boramae Hospital, Seoul, Korea, Republic of, 6Department of Life Science, Multidisciplinary Genome Institute, Hallym University, Chuncheon, Korea, Republic of

    *Purpose: Kidney transplantation (KT) is the best treatment for end-stage renal disease. Although rejection is a normal immune response of the body to a foreign…
  • 2020 American Transplant Congress

    Late Onset Primary Graft Dysfunction after Lung Transplantation Correlates with Transplant Arteriosclerosis in a Humanized Mouse Model

    M. Franz1, T. Siemeni1, A. Knöfel1, W. Sommer1, M. Avsar1, F. Ius1, I. Tudorache1, C. Kühn1, C. S. Falk2, G. Warnecke1, A. Haverich1

    1Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany, 2IFB-Tx, Hannover Medical School, Hannover, Germany

    *Purpose: Primary Graft dysfunction (PGD) is one of the most important causes of early mortality after lung transplantation. We investigated the correlation between the incidence…
  • 2020 American Transplant Congress

    Incidence, Risk Factors, and Kidney Transplant Outcomes Associated with Post-Transplant Diabetes Mellitus

    R. F. Malik1, Y. Jia1, S. G. Mansour2, I. E. Hall2, M. D. Doshi2, P. P. Reese2, P. Singh2, M. N. Harhay2, F. L. Weng2, H. Thiessen Philbrook1, B. Schröppel2, T. Muthukumar2, J. S. Bromberg2, E. Akalin2, S. Mohan2, C. R. Parikh1

    1Johns Hopkins University, Baltimore, MD, 2DDS Consortium, Baltimore, MD

    *Purpose: Post-Transplant Diabetes Mellitus (PTDM) is a common complication after kidney transplant (KT). Most prior studies are single-center with short follow-up and inconsistent outcome ascertainment.…
  • 2020 American Transplant Congress

    Ranking Eplet Mismatches as Predictors of Graft Failure

    W. Zhang1, H. Mohammadhassanzadeh1, K. Oualkacha2, H. Gebel3, W. Klement4, R. Sapir-Pichhadze1

    1McGill University, Montreal, QC, Canada, 2UQAM, Montreal, QC, Canada, 3Emory University Hospital, Atlanta, GA, 4Canadian Blood Services, Ottawa, ON, Canada

    *Purpose: Donor:recipient matching at the level of sequence defined HLA targets (eplets) is being promoted as a biologically sound strategy to prevent graft failure. Because…
  • 2020 American Transplant Congress

    Incidence and Risks Factors of Kidney Allograft Loss Due to BK Virus in Pediatric Population: UNOS Data Set

    H. Patel1, K. Agrawal1, A. Pawar1, N. Rodig2, N. Agrawal1, F. Cardarelli1

    1Transplant Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, 2Nephrology (Medicine), Boston Children's Hospital, Boston, MA

    *Purpose: BK virus infection can lead to graft dysfunction and loss in kidney transplant patients. Incidence and prevalence of BK Viremia (BKV) and BK Virus…
  • 2020 American Transplant Congress

    Establishment of Spontaneous Tolerance of Kidney Allografts is Dependent on Mitigation of Ischemia-Reperfusion Injury via the BLTA-HVEM Pathway

    Q. Yuan1, S. Hong1, E. Szuter1, Y. Zhao1, E. Acheampong1, I. Rosales1, M. Kronenberg2, P. Russell1, J. Madsen1, R. Colvin1, A. Alessandrini1

    1Massachusetts General Hospital, Boston, MA, 2La Jolla Institute for Allergy & Immunology, La Jolla, CA

    *Purpose: Kidney allografts transplanted across certain mouse strain combinations (e.g. DBA/2 to B6) develop tolerance while other combinations do not (e.g. B6 to DBA/2). We…
  • 2020 American Transplant Congress

    Long-Term Kidney Graft Survival is Superior with Simultaneous-Liver Kidney (SLK) Transplants Than Kidney Alone (KA) or Kidney after Liver (KALi) Transplants in the United States

    N. Lim1, S. M. Riad1, S. Jackson2, J. Lake1

    1University of Minnesota, Minneapolis, MN, 2M Health Fairview, Minneapolis, MN

    *Purpose: There is a concern that SLK transplant recipients have worse outcomes resulting in poor utilization of the kidney donor pool. We utilized the Scientific…
  • 2020 American Transplant Congress

    Low Mycophenolic Acid Levels are Associated with More Inflammation on 1 Year Protocol Biopsies and Lower Graft Survival in Kidney Transplant Recipients

    J. Huskey, G. Mour, M. Ryan, S. Nair, M. Smith, R. Heilman

    Mayo Clinic Arizona, Phoenix, AZ

    *Purpose: Data is limited on the association of Mycophenolic Acid (MPA) concentration on protocol kidney transplant biopsies. Our aim is to compare clinical outcomes and…
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