2016 American Transplant Congress
Predictors of Early Rejection and Allograft Failure in Pediatric Kidney Transplantation: Impact of Histology and Behavior.
University of Alabama at Birmingham School of Medicine, Birmingham.
Background: Early inflammatory events that lead to allograft dysfunction are often missed by creatinine-based estimates in children. Surveillance biopsies can detect early allograft dysfunction due…2016 American Transplant Congress
Chronic Infection by Hepatitis C Virus and the Development of Transplant Glomerulopathy.
OBJETIVE: To demonstrate that chronic infection with the hepatitis C virus (HCV) is a risk factor for the development of transplant glomerulopathy in a large…2016 American Transplant Congress
Standardized Pre-Implantation Kidney Biopsies of Expanded Criteria Donors to Improve the Kidney Donor Profile Index (KDPI) for the Evaluation of Marginal Donors.
There is no consensus of selection criteria used to allocate renal transplants from expanded criteria donors (ECD). The Kidney Donor Profile Index (KDPI) has been…2016 American Transplant Congress
Everolimus with Low-Dose Tacrolimus vs. a Standard Immunosuppressive Regimen: Renal Histology at 6 Months in De Novo Renal Transplant Patients.
Morphologic changes in transplant protocol biopsies provide early evidence of renal damage. This study examined the renal histology of de novo patients 6 months post…2016 American Transplant Congress
Long-Term Deterioration of Graft Function (DeKAF) Study: Histologic Interpretation of Cross-sectional vs Prospective Cohorts.
1U of MN, Mpls, MN; 2U IA, Iowa City, IA; 3Mayo, Rochester, MN.
The major aim of the DeKAF study was to define previously unidentified phenotypes resulting in late graft dysfunction and loss (GL). Two cohorts were developed,…2016 American Transplant Congress
Elevated Intragraft Expression of Innate Immunity and Cell Death-Related Markers Characterizes Deceased Donor Conditions and Is a Risk Factor for Adverse Graft Outcome.
Background: The innate immune response is increasingly being recognized in allograft injury after kidney transplantation. We aimed to establish the relationship of innate immune gene…2016 American Transplant Congress
The Quilty Effect in Pediatric Heart Transplant Recipients.
Purpose: The Quilty effect is defined as the presence of a nodular endocardial infiltrate of lymphocytes in an endomyocardial biopsy (EMB), and has been described…2016 American Transplant Congress
The Effect of Everolimus and Tacrolimus Exposure Levels on Renal Histology Parameters 6 Months Post-Transplantation.
We examined renal histology scores in patients with different exposure levels of everolimus (EVR) and tacrolimus (TAC) over 6 months.Renal transplant patients (N=613) were randomized…2016 American Transplant Congress
IFTA Is Linked to Urinary Microbiome Changes.
Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA.
Purpose: The microbiome is important to human health and alteration may lead to aberrant immunity and disease. Interstitial fibrosis and tubular atrophy(IFTA) occurs in 20%…2016 American Transplant Congress
Is Pretransplant Determination of Hepatocellular Carcinoma Tumor Grade Using Needle Biopsy Reliable for Transplant Candidate Selection? Analysis of 217 Liver Transplant Recipients.
Department of Surgery, UCLA, Los Angeles, CA.
Objective: Despite the prognostic significance of tumor grade and vascular invasion for patients with hepatocellular carcinoma (HCC), preoperative needle biopsy (PNB) is not routinely utilized…
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