Articles tagged "Bile duct"

2019 American Transplant Congress
Pharmacological Enhancement of Bile Duct Preservation and Function during Ex-Situ Normothermic Machine Perfusion
Y. L. Boteon, J. Attard, A. P. Boteon, L. Wallace, G. Reynolds, D. Mirza, H. Mergental, R. Bhogal, S. Afford
Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom
*Purpose: Whilst ex-situ normothermic machine perfusion (NMP) of the liver limits the ischaemic injury to the organ, benefits for biliary complications post-transplantation are not yet…
2019 American Transplant Congress
Normothermic Ex-Situ Liver Perfusion Parameters of Liver Viability in a Porcine Model of Liver Transplantation with Marginal Grafts
I. Linares-Cervantes¹, J. Echeverri¹, S. Cleland¹, M. Kaths¹, R. Rosales¹, T. Goto¹, D. Kollmann¹, M. Hamar¹, P. Urbanellis¹, L. Mazilescu¹, S. Ganesh¹, O. Adeyi¹, P. Yip¹, B. Bojko², P. Gorynzka², K. Gorynski², D. Grant¹, N. Selzner¹, M. Wasowicz¹, M. Selzner¹
¹Toronto General Hospital, Toronto, ON, Canada, ²University of Nicolaus Copernicus, Torun, Poland
*Purpose: Evaluate parameters of liver viability during normothermic ex-situ liver perfusion (NEsLP) prior to transplantation.*Methods: In this study, we investigated prior assessed parameters and new…
2019 American Transplant Congress
Bile Duct Anastomosis over Intraluminal Plastic Biliary Stent in Liver Transplant: Clinical Outcome
H. Samant¹, K. Patel¹, W. Manatsathit², N. Singh¹, H. S. Amiri³, G. Zibari³
¹Louisiana State University and Health Science Center, Shreveport, LA, ²University of Nebraska Meical Center, Omaha, NE, ³John C McDonald Transplant Center, Shreveport, LA
*Purpose: Biliary complications have been known as “Achilles Heel” of orthotropic liver transplantation (OLT) with high morbidity and mortality. Intra-luminal plastic biliary stents replacing T-tubes…
2019 American Transplant Congress
Insertion of Internal Stent in Duct-to-Duct Biliary Reconstruction to Reduce Bile Duct Complication in Living Donor Liver Transplantation
H. Choi¹, G. Na²
¹Surgery, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea, Republic of, ²Surgery, Bucheon St. Mary's Hospital, The Catholic University of Korea, Bucheon, Korea, Republic of
*Purpose: Because of the innovations in surgical and postoperative surgical treatment of donors and recipients during the past decade, living donor liver transplantation (LDLT) is…
2018 American Transplant Congress
Staged Biliary Reconstruction after Liver Transplantation Reduces Post-Transplant Biliary Complications in High-Acuity Patients
T. Pearson, M. Zimmerman, J. Kim, P. Palines, M. Wong, C. Erickson, J. Hong.
Medical College of Wisconsin, Milwaukee, WI.
Biliary complications (BC) after liver transplantation (LT) are strongly associated with inferior patient outcomes and increased healthcare cost. High-acuity LT patients are at increased risk…
2018 American Transplant Congress
Early Biliary Complications after Orthotopic Liver Transplantation – Non-Randomised Comparison of 3 Methods of Biliary Tract Drainage
A. Jóźwik,¹ M. Kosieradzki,¹ B. Łągiewska,¹ W. Lisik,¹ E. Karpeta,¹ J. Bednarek,² M. Zaborska,² J. Trzebicki,³ M. Pacholczyk.¹
¹Department of General and Transplantation Surgery, Medical University of Warsaw, Warsaw, Poland; ²Medical University of Warsaw, Warsaw, Poland; ³I Department of Anaesthesiology and Intensive Care, Medical University of Warsaw, Warsaw, Poland.
BackgroundBiliary tract complications (BTC) are still relatively common and complex problem following orthotopic liver transplantation (OLT). The aim of this nonrandomized study was to evaluate…
2018 American Transplant Congress
Does Biliary Duct Reconstruction Technique Impact Liver Transplantation Outcomes?
R. Shahbazov,¹ M. Kessel,² K. Knapp,² F. Azari,² S. Tsutsui,³ A. Nickkholgh,¹ D. Maluf,¹ S. Pelletier.¹
¹Surgery, University of Virginia Health System, Charlottesville, VA; ²School of Medicine, University of Virginia Health System, Charlottesville, VA; ³Surgery, University of Pennsylvania, Philadelphia, PA.
Introduction: The rate of biliary complication after liver transplantation remains high. The choice of biliary reconstruction technique may depend on the patient's primary disease, possible…
2018 American Transplant Congress
DCD Utilization in Cholestatic Liver Disease: Distinct Outcomes between PSC and PBC Recipients
J. Pasko, E. Maynard, E. Dewey, K. Roayaie, S. Orloff, D. Scott, W. Naugler, J. Ahn, C. Enestvedt.
Abdominal Transplant Surgery, Oregon Health & Science University, Portland, OR.
Background: Concern for inferior outcomes in patients with primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) have limited utilization of donation after cardiac death…
2018 American Transplant Congress
Cost Analysis of Biliary Strictures Following Orthotopic Liver Transplantation in the United States
J. Jones,¹ N. Bhutiani,¹ D. Wei,² L. Goldstein,³ R. Martin,¹ C. Jones,¹ R. Cannon.¹
¹Surgery, University of Louisville, Louisville, KY; ²Real-world Data Analytics and Research, Johnson & Johnson, New Brunswick, NJ; ³Health Economics and Market Access, Ethicon, Inc., Somerville, NJ.
Introduction: While previous studies have evaluated risk factors, management, and outcomes in patients who develop biliary strictures (BS) after undergoing orthotopic liver transplantation (OLT), none…
2018 American Transplant Congress
Biliary pH, Bicarbonate and Glucose Are Suitable Biomarkers of Bile Duct Viability during Normothermic Machine Perfusion of Human Donor Livers
A. Matton,^1,2 Y. de Vries,^1,2 L. Burlage,^1,2 R. van Rijn,^1,2 A. Gouw,³ V. de Meijer,¹ T. Lisman,² R. Porte.¹
¹Department of Surgery, Section Hepatopancreatobiliary Surgery & Liver Transplantation, University Medical Center Groningen, University of Groningen, Groningen, Netherlands; ²Surgical Research Laboratory, University Medical Center Groningen, University of Groningen, Groningen, Netherlands; ³Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Background: Normothermic machine perfusion (NMP) is rapidly making its way into the clinic and can be used for viability assessment of human donor livers prior…