Articles tagged "Bile duct"

2019 American Transplant Congress
Management of Anastomotic Biliary Strictures after Liver Transplant: Role of Covered Metal Stents
A. Watson¹, K. Haq¹, K. Khorfan², S. Singla¹, A. Yoshida³, D. Moonka¹
¹Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI, ²Internal Medicine, Henry Ford Hospital, Detroit, MI, ³Transplant Institute, Henry Ford Hospital, Detroit, MI
*Purpose: Biliary complications, including anastomotic biliary strictures (ABS), remain the most common cause of morbidity in liver transplant (LT) patients. Endoscopic therapy has become the…
2019 American Transplant Congress
Epithelial to Mesenchymal Transition: A Cellular Mediator of Ischemic Cholangiopathy after Liver Transplant
N. A. Wickramaratne¹, R. Li², R. C. Fyffe-Freil², T. Tian², M. J. Mangino²
¹VCUHealth, Richmond, VA, ²Department of Surgery, VCUHealth, Richmond, VA
*Purpose: Epithelial-to-mesenchymal transition (EMT) is a genetic reprogramming that causes epithelial cells to assume a migratory, mesenchymal phenotype, and it is induced by hypoxia. Ischemic…
2019 American Transplant Congress
Ischemia-Free Liver Transplantation Protects Bile Duct from Ischemia/Reperfusion Injury
J. Yang, S. Huang, Z. Zhang, Q. Zhao, W. Ju, Z. Zhu, Y. Tang, L. Wang, Y. Zhang, C. Sun, L. Wu, Z. Guo, X. He
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: Ischemia-free liver transplantation (IFLT), based on normothermic machine perfusion and innovations in surgical technique, can provide continue blood supply from procurement to implantation that…
2019 American Transplant Congress
Pharmacological Enhancement of Bile Duct Preservation and Function during Ex-Situ Normothermic Machine Perfusion
Y. L. Boteon, J. Attard, A. P. Boteon, L. Wallace, G. Reynolds, D. Mirza, H. Mergental, R. Bhogal, S. Afford
Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom
*Purpose: Whilst ex-situ normothermic machine perfusion (NMP) of the liver limits the ischaemic injury to the organ, benefits for biliary complications post-transplantation are not yet…
2019 American Transplant Congress
Normothermic Ex-Situ Liver Perfusion Parameters of Liver Viability in a Porcine Model of Liver Transplantation with Marginal Grafts
I. Linares-Cervantes¹, J. Echeverri¹, S. Cleland¹, M. Kaths¹, R. Rosales¹, T. Goto¹, D. Kollmann¹, M. Hamar¹, P. Urbanellis¹, L. Mazilescu¹, S. Ganesh¹, O. Adeyi¹, P. Yip¹, B. Bojko², P. Gorynzka², K. Gorynski², D. Grant¹, N. Selzner¹, M. Wasowicz¹, M. Selzner¹
¹Toronto General Hospital, Toronto, ON, Canada, ²University of Nicolaus Copernicus, Torun, Poland
*Purpose: Evaluate parameters of liver viability during normothermic ex-situ liver perfusion (NEsLP) prior to transplantation.*Methods: In this study, we investigated prior assessed parameters and new…
2019 American Transplant Congress
Bile Duct Anastomosis over Intraluminal Plastic Biliary Stent in Liver Transplant: Clinical Outcome
H. Samant¹, K. Patel¹, W. Manatsathit², N. Singh¹, H. S. Amiri³, G. Zibari³
¹Louisiana State University and Health Science Center, Shreveport, LA, ²University of Nebraska Meical Center, Omaha, NE, ³John C McDonald Transplant Center, Shreveport, LA
*Purpose: Biliary complications have been known as “Achilles Heel” of orthotropic liver transplantation (OLT) with high morbidity and mortality. Intra-luminal plastic biliary stents replacing T-tubes…
2019 American Transplant Congress
Insertion of Internal Stent in Duct-to-Duct Biliary Reconstruction to Reduce Bile Duct Complication in Living Donor Liver Transplantation
H. Choi¹, G. Na²
¹Surgery, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea, Republic of, ²Surgery, Bucheon St. Mary's Hospital, The Catholic University of Korea, Bucheon, Korea, Republic of
*Purpose: Because of the innovations in surgical and postoperative surgical treatment of donors and recipients during the past decade, living donor liver transplantation (LDLT) is…
2019 American Transplant Congress
Management of Orphan Ducts After Pediatric Living Donor Liver Transplantation
N. Celik¹, A. Ganoza², A. Khanna², G. Bond², K. Soltys², R. Sindhi², J. Crowley³, A. Humar¹, G. Mazariegos²
¹Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, ²Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ³Department of Radiology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA
*Purpose: Living donor (LDLT) and split (SLT) livers are two technical variants of standard liver transplants that potentially increase the number of liver allografts available…
2019 American Transplant Congress
Scaffold-Free 3D-Bioprinting of Human Extrahepatic Bile Duct
K. Saglam¹, W. Zhang¹, L. J. Smith², A. Isidan¹, A. M. Chen¹, R. A. Naqvi¹, E. Gramelspacher¹, P. Li¹, B. Ekser¹
¹Transplant Division, Department of Surgery, Indiana University, Indianapolis, IN, ²3D-Bioprinting Core, Indiana University School of Medicine, Indianapolis, IN
*Purpose: Biliary complications are common especially in living and also in deceased donor liver transplantation (LT). Presence of multiple orifices in biliary anastomosis and ischemia,…
2019 American Transplant Congress
Hepatopancreatobiliary Training In Transplant Fellowships: H And B, Maybe?
R. Borscheid¹, A. Saharia², E. Cho¹, F. Lewis¹, H. Osman¹, J. Kurtz¹, D. Jeyarajah¹, A. Gaber²
¹Methodist Richardson Medical Center, Richardson, TX, ²Houston Methodist Hospital, Houston, TX
*Purpose: HPB surgery is an evolving specialty, but only about 15% of the active HPB surgeons have undergone training in a dedicated HPB program -…