2020 American Transplant Congress » Poster Session D: Cellular Therapies, Tissue Engineering / Regenerative Medicine

3:30pm-4:00pm

3D Bioprinted Intrahepatic Cholangiocarcinoma Model and 7-Day Perfusion with Gemcitabine and Cisplatin: Modeling the Tumor Microenvironment and Response to Chemotherapy

A. M. Chen¹, W. Zhang¹, J. Sterner², L. Kennedy³, A. Isidan¹, E. Gramelspacher¹, H. L. Francis³, G. Alpini³, L. J. Smith², P. Li¹, B. Ekser¹

3:30pm-4:00pm

ANG-3777, A Hepatic Growth Factor Mimetic, Attenuates Mercuric Chloride-Induced Renal Dysfunction and Mortality in Rats

P. Narayan, I. D. Goldberg

3:30pm-4:00pm

Antibody-Suppressor CD8⁺ T Cells Ameliorate Antibody-Mediated Rejection Following Kidney Transplant in Mice

J. M. Zimmerer¹, J. L. Han¹, Q. Zeng², B. A. Ringwald¹, C. Cassol¹, R. Warren¹, M. Abdel-Rasoul¹, C. K. Breuer², G. L. Bumgardner¹

3:30pm-4:00pm

Biointegration and Function of 3D Printed Bionic Pancreatic Petals on a Mouse Model

M. Wszola¹, M. Klak¹, G. Tymicki¹, A. Berman¹, K. Kosowska¹, T. Bryniarski¹, P. Cywoniuk¹, M. Gomolka¹, P. Kowalska¹, P. Turowski¹, A. Kaminski²

3:30pm-4:00pm

Building Kidneys from Stem Cells for Transplantation

I. M. Rogers¹, J. Whiteley², T. Chow², T. Bongolan², L. Mazilescu³, P. Urbanellis³, S. Ganesh³, M. Selzner³

3:30pm-4:00pm

Challenges in Manufacturing Clinically Competent Regulatory T Cells from Obese Renal Transplant Recipients

F. Marti, A. Ruffing, E. Chacon, L. Turcios, D. Valvi, J. Gonzalez, R. Gedaly

3:30pm-4:00pm

Characterization of a Clinically Scaled Bioengineered Liver Seeded with Primary Hepatocytes and Endothelial Cells

D. S. Davidow¹, J. J. Ross¹, B. D. Anderson¹, A. Stumbras¹, A. A. Katane¹, R. Lindeman¹, B. G. Steiner¹, A. Mendenhall¹, K. Gahlbeck¹, S. Armstrong¹, B. P. Amiot², E. D. Nelson², T. Gilbert¹, S. L. Nyberg²

3:30pm-4:00pm

Concept Discussion: Five Experimental Stages to Establish the Methodologies for Organ Farming

R. F. Smith

3:30pm-4:00pm

Construction of Three-Dimensional Vascularized Functional Beta-Cells Tissues Using a Layer-by-Layer Cell Coating Technique

S. Takaichi¹, T. Akagi², Y. Tomimaru¹, S. Kobayashi¹, Y. Iwagami¹, H. Akita¹, T. Noda¹, K. Gotoh¹, Y. Doki¹, M. Akashi², H. Eguchi¹

3:30pm-4:00pm

Development and Cell Surface Testing of a Novel Nanofiber Technology for Targeted Delivery of Therapeutic Regulatory T Cells

J. M. Mathew¹, S. Lee², Y. Sambandam¹, L. A. Fraser², T. D. Clemons², A. Kolberg², J. He¹, L. C. Palmer², M. T. McClendon², Z. J. Zhang¹, J. R. Leventhal¹, S. I. Stupp², L. Gallon¹

3:30pm-4:00pm

Development of a Novel Multidrug Combination to Defat Steatotic Rat Liver via Normothermic Machine Perfusion

M. Xu¹, F. Zhou¹, O. Ahmed¹, G. Upadhya¹, J. Jia¹, C. Lee¹, J. Xing¹, L. Ye¹, S. Shim¹, Z. Zhang¹, K. Byrnes², B. Wong¹, J. Kim¹, Y. Lin¹, W. Chapman¹

3:30pm-4:00pm

Epithelial To Mesenchymal Transition Mediates Engraftment Of Endoderm And Hepatic Progenitor Cells In The Quiescent Liver

W. S. Fagg¹, N. Lui², L. Patrikeev³, O. Saldarriaga*⁴, H. Lerner-Stevenson⁵, V. Popov⁶, M. Motamade³, J. H. Fair¹

3:30pm-4:00pm

Formation Of Artificial Blood Vessels Using ECM In 3D Bioprinting

P. Cywoniuk, T. Bryniarski, T. Dobrzanski, K. Kosowska, M. Klak, G. Tymicki, P. Kowalska, M. Gomolka, P. Turowski, I. Zamora, A. Berman, M. Wszola

3:30pm-4:00pm

Gal9/Tim-3 Pathway was Required for Endometrial Stem Cells to Induce Peripheral Tolerance of Cardiac Allograft

Y. Zhao¹, Y. Hu¹, D. Yu¹, X. Li¹, W. Jin¹, Y. Qin¹, D. Kong¹, H. Wang¹, A. Alessandrini², H. Wang¹

3:30pm-4:00pm

Immune Response Following Cardiac Progenitor Cells Transplantation in Rat Myocardial Infarction Model

M. Gunasekaran, R. Mishra, S. Sharma, P. Saha, L. Wang, M. Yasir Arfat, X. Fu, S. Kaushal

3:30pm-4:00pm

Impact of Extracorporeal Photopheresis in a Full-Mismatch Kidney Transplant Rat Model

J. Rovira¹, G. J. Piñeiro², M. Lazo-Rodriguez³, M. J. Ramirez-Bajo¹, E. Banon-Maneus³, N. Hierro-Garcia³, P. Ventura-Aguiar², J. Cid⁴, M. Lozano⁴, F. Diekmann²

3:30pm-4:00pm

Improved Survival of Acute Liver Failure by “Off-the-Shelf” Bioartificial Liver Support System Using Immobilized Cryopreserved Hepatocyte Spheroids in Porcine Model

S. Lee¹, J. Lee², H. Park², Y. Kim², J. Noh³, J. Jung³, S. Lee³, H. Shin³, H. Yoon⁴, D. Lee³, S. Lee¹

3:30pm-4:00pm

Ischemic and Perfused Kidney Treated with Non-Cultured Adipose-Derived Regenerative Cells Increase the Immune and Regulatory Transcriptome

R. Lathan¹, R. Ghita¹, R. Touyz¹, M. Clancy², P. Mark¹

3:30pm-4:00pm

Novel Mechanism of Immune Evasion by Human Neonatal Cardiac Progenitor Cells Recovers Ailing Myocardium in Rat Myocardial Infarct Model

M. Gunasekaran, R. Mishra, S. Sharma, P. Saha, L. Wang, M. Yasir Arfat, L. Davidson, X. Fu, A. Shah, M. Abdullah, D. Li, S. Kaushal

3:30pm-4:00pm

Potential to Regenerate Damaged Allografts

L. Brasile¹, B. Stubentisky²

3:30pm-4:00pm

Production of Detergent-Free ECM-Derived Bioinks for Bioprinting of Bionic Pancreas Ready for Clinical Use

M. Wszola¹, M. Klak¹, G. Tymicki¹, A. Berman¹, K. Kosowska¹, T. Bryniarski¹, P. Cywoniuk¹, M. Gomolka¹, P. Kowalska¹, P. Turowski¹, A. Kaminski²

3:30pm-4:00pm

Prolonged Functional Human 3D Liver Organoids as an In Vitro Liver Disease Model

W. Zhang¹, A. Isidan¹, A. M. Chen¹, L. J. Smith², H. L. Francis³, G. Alpini³, E. Gramelspacher¹, P. Li¹, B. Ekser¹

3:30pm-4:00pm

The Liver Regenerative Effect of Substance P after Major Hepatectomy in Rat Models

H. Ahn¹, Y. Kim¹, O. Kwon²

3:30pm-4:00pm

The Therapeutic Potential of Human Liver-Derived Stem Cells Transplantation in Carbon Tetrachloride-Induced Rat Liver Cirrhotic Model

S. Lee¹, J. Lee², H. Park², Y. Kim², S. Lee¹

3:30pm-4:00pm

Tracking Tregs in a Non-Human Primate Model with Expanded Autologous Treg Infusions In Vivo

K. Bruestle¹, B. Piegari¹, H. Sakai¹, F. Fredriksson¹, D. Ekanayake-Alper¹, S. Robertson², D. Hajosi², J. Weiner¹, A. Iuga³, S. M. Coley³, M. Sykes¹, A. Griesemer¹

3:30pm-4:00pm

Treg Stability Depends on Lymphotoxin Beta Receptor-Driven Migration

V. Saxena, W. Piao, L. Li, Y. Xiong, C. Palusckievicz, T. Simon, M. Shirkey, R. Abdi, J. S. Bromberg

3:30pm-4:00pm

What Happens When You Administer Mesenchymal Stromal Cells During Normothermic Machine Perfusion of Porcine Kidneys: Possible and Helpful or Not?

K. Rozenberg¹, L. Knijff¹, J. Sierra-Parraga², L. Lo Faro¹, M. Hoogduijn², C. Baan², J. Hunter¹, R. Ploeg¹