2018 American Transplant Congress

June 2-6, 2018 in Seattle, WA

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Haematological Autoimmune Disorders Associated with Alemtuzumab Induction in Renal and Simultaneous Pancreas and Kidney Recipients

A. Kousios,¹ R. Charif,¹ M. Atta,² A. Luqmani,² N. Cooper,² D. Taube.¹
Hard-To-Place Kidney Offers: Granular Examination of Donor Risk Factors for Discard

R. Narvaez, J. Nie, K. Noyes, M. Leeman, L. Kayler.
Hard-To-Place Kidney Offers: System- Level Predictors of Discard

L. Kayler,¹ J. Nie,² K. Noyes,² M. Leeman,³ R. Narvaez.¹
Having Your Cake and Eating It Too: An Aggressive Protocol for DSA Treatment Does Not Doom Patients to High Infectious Risk

A. Murthy, A. Karaballa, G. Vranic, B. Javaid, J. Moore, S. Yi, J. Verbesey, P. Abrams, S. Ghasemian, M. Cooper, A. Gilbert.
HCV Ab+/NAT- Organ Donors, and the Challenges of 'Eclipse Windows': Analysis of the OPTN/UNOS Ad Hoc Disease Transmission Advisory Committee (DTAC)

C. Wolfe, S. Tlusty, G. Vece, R. Sawyer, R. Bag, G. Berry, J. Bucio, L. Danziger-Isakov, D. Goldberg, C. Ho, D. Florescu, D. Klassen, R. La Hoz, K. Lilly, A. Mehta, M. Malinis, M. Nalesnik, N. Theodoropoulos, P. Wood, M. Michaels.
Health and Economic Disparities in Waitlist Access and Liver Distribution Policy

R. Lynch,¹ K. Ross,¹ T. Pearson,¹ D. Goldberg,² R. Patzer.¹
Heart En Bloc Thymus Cotransplantation in NHPs Controls Cellular but Not Humoral Alloreactivity

W. Sommer, J. O., K. Pruner, J. Paster, M. Hanekamp, A. Dehnadi, I. Rosales, R. Smith, R. Colvin, G. Benichou, J. Allan, J. Madsen.
Heart and Lung Offer Acceptance Practices Are Associated with Organ Yield and Local Placement

A. Wey, M. Skeans, N. Salkowski, B. Kasiske, A. Israni, J. Snyder.
Heart and Lung Transplantation Outcomes in HIV-Positive Recipients

C. Koval,¹ M. Malinis,² N. Mueller,³ J. Krisl,⁴ M. Hannan,⁵ P. Grossi,⁶ S. Huprikar.⁷
Heart Transplant across Low or Moderate Level Donor-Specific Antibodies Have Acceptable Outcome

M. Olymbios, J. Patel, R. Levine, S. Dimbil, M. Kittleson, M. Rafiei, X. Zhang, J. Kobashigawa.
Heart Transplantation in Patients with Complex Congenital Heart Disease

M. Kittleson, J. Patel, E. Kransdorf, S. Dimbil, R. Levine, D. Geft, D. Chang, L. Czer, J. Kobashigawa, R. Garg, E. Zahn.
Hematopoietic Cell Kinase (Hck) Regulates Effector and Regulatory T Cell (Treg) Function

S. Farouk,¹ C. Wei,¹ B. Das,² P. Cravedi,¹ B. Murphy.¹
Hemodialysis Catheter-Related Right Atrial Thrombus Detected Prior to Kidney Transplantation

S. Jeung, H. Kim, C. Baek, S-.K. Park.
Hemodynamic and Functional Analysis of Human DCD Hearts Undergoing Normothermic Ex Vivo Perfusion

W. Sommer, N. Roy, S. Kilmarx, J. O., J. Titus, M. Villavicencio, J. Stone, J. Madsen, D. D'Alessandro.
Hepatic Artery Resistive Indices on Doppler Ultrasound at Long Term Follow Up in Liver Transplant Recipients: Importance and Implications

P. Serrano Rodriguez, L. Cramer, K. Jones, E. Lemmon, T. Masakadza, A. Milukas, R. Watkins, D. Gerber, C. Desai.
Hepatitis C Recurrence after Liver Transplant: A Comparison of Antibody Induction versus No Antibody Induction

S. Patel, J. Jin, E. Benedetti, P. West-Thielke.
hEPCR.hTBM.hCD47.HO-1 Contributes to Increased Survival, Reduced Platelet Sequestration, and Modulation of Coagulation Activation in GalTKO.hCD46 Porcine Livers Perfused with Human Blood

A. Cimeno,¹ L. Burdorf,¹ D. Ayares,² A. Azimzadeh,¹ R. Pierson III,¹ R. Barth,¹ J. LaMattina.¹
Hidden Risk of Liver Transplantation for Nonalcoholic Steatohepatitis: A Propensity Score Matched Study

S. Nagai,¹ R. Schilke,¹ M. Safwan,¹ M. Rizzari,¹ K. Collins,¹ A. Yoshida,¹ M. Abouljoud,¹ D. Moonka.²
High Body Mass Index in Organ Donor is Significantly Correlated to Low PaO₂/FiO₂ Ratio in SRTR Database

T. Okamoto,¹ L. Thuita,¹ H. Niikawa,¹ K. Ayyat,¹ Y. Itoda,¹ M. Valpour,² E. Blackstone,¹ K. McCurry.¹
High Calcineurin Inhibitor Intra Patient Variability is Associated with Early Renal Allograft Inflammation, Chronicity and Loss

A. Sharma,¹ A. Cherukuri,² R. Mehta,¹ P. Sood,¹ S. Hariharan.¹
High Dose Tissue Plasminogen Activator Flush during Donation-after-Cardiac-Death (DCD) Liver Procurements Offers Optimal Outcomes

J. Torabi,² J. Graham,^1,2 S. Bellmare,^1,2 M. Kinkhabwala,^1,2 J. Rocca.^1,2
High Fibre Diet Induces Donor Specific Kidney Allograft Tolerance in Mice

H. Wu,^1,2 T. Kwan,² Y. Loh,² C. Wang,² L. Macia,² S. Alexander,^2,3 S. Chadban.^1,2
High Frequency of HLA-DQ De Novo Donor Specific Antibodies is Independent of the Number of Mismatches in Heart Transplant

X. Zhang,¹ E. Kransdorf,² J. Patel,² J. Kobashigawa.²
High GFR in Kidney Donors is Associated with Increased Risk of Proteinuria and Diabetes

D. Keys, S. Riad, V. Vakil, S. Jackson, D. Berglund, A. Matas.
High Grade Cytomegalovirus Viremia Events in Solid Organ Transplant Recipients: Description and Quality Improvement

M. Spinner,¹ V. Athans,¹ C. Koval.²
High Kidney Donor Profile Index (KDPI) Donor Kidneys: Use Them, Don't Lose Them!

D. Harriman, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, M. Gautreaux, W. Doares, S. Kaczmorski, R. Stratta.
High Prevalence of Hypertension and Alterations in Rhythmicity in Recipients of Pediatric Transplants

N. Memaran,¹ M. Kirchner,² R. Blöte,¹ B. Maecker-Kolhoff,³ I. Goldschmidt,¹ C. Müller,⁴ J. Epping,⁵ R. Sugianto,¹ B. Borchert,¹ B. Schmidt,⁶ E. Wühl,⁷ A. Melk.¹
High Prevalence of Kidney Transplant-Associated Thrombotic Microangiopathy after ABO-Incompatible Kidney Transplantation: Risk Factors, Rapid Clinical Diagnosis, and Prompt Successful Treatment

K. Tanabe,¹ M. Okumi,¹ K. Unagami,² Y. Kakuta,¹ M. Inui,¹ H. Ishida.¹
High Prevalence of New Onset Diabetes Mellitus in a Predominantly Minority Urban Cohort of Kidney Transplant Recipients and Clinical Outcomes

S. Aleksic, S. Zahedpour, E. Tsomos, M. Ajaimy, J. Zonszein, E. Akalin.
High Serum Resistin Levels Predict Future Acute Kidney Injury in Kidney Transplantation Patients

M-.C. Lee,^1,3 B-.G. Hsu.^2,3
High Tacrolimus Variability is Associated with Worse Outcomes in Pediatric Renal Transplant Recipients

S. Solomon, M. Del Rio, A. Colovai, N. Hayde.
Higher Concordance in the Incidence of DGF and Post-Transplant BKV Infection among Recipients Receiving Mate Kidneys from the Same Deceased Donor: A Paired Deceased Donor Kidney Transplant Analysis

K. Venkatesh,¹ C. Wu,¹ C. Puttarajappa,¹ R. Mehta,¹ P. Sood,¹ A. Tevar,² S. Hariharan.¹
Higher Early Post-Liver Transplant Mortality in Recipients with Severe Alcoholic Hepatitis versus Alcoholic Cirrhosis

B. Lee, G. Im, J. Dodge, M. Voigt, J. Rice, M. Lucey, D. Foley, L. Platt, A. Gurakar, N. Mehta, G. Therapondos, H. Han, D. Victor, O. Fix, L. Dinges, D. Dronamraju, C. Hsu, M. Rinella, H. Maddur, S. Eswaran, J. Hause, R. Ghobrial, Z. Li, N. Terrault.
Higher Rates of Rejection in HIV-Infected Kidney Transplant Recipients on Ritonavir-Boosted Protease Inhibitors–Three-Year Follow Up

B. Rollins, S. Farouk, G. DeBoccardo, S. Lerner, M. Rana, S. Huprikar, L. Miko, V. Delaney, S. Florman, R. Shapiro.
Highly Correlative Whole-Tissue Gene/protein Signatures to Score FFPE Transplant Biopsies with Inflammation and Acute Rejection

T. Sigdel, M. Nguyen, D. Dobi, S-.C. Hsieh, J. Liberto, F. Vincenti, Z. Laszik, M. Sarwal.
Hispanics' Perceptions of a Culturally Targeted Transplant Program: A Mixed Methods Study

N. Alhalel,¹ N. Francone,¹ J. Caicedo,¹ R. Ruiz,² A. Salazar,² S. Primeaux,² E. Gordon.¹
Hispanics' Perceptions of Shared Decision Making in the Transplant Context: A Mixed Methods Study

N. Alhalel,¹ J. Caicedo,¹ R. Ruiz,² A. Salazar,² S. Primeaux,² E. Gordon.¹
Histogenomics: Molecular Profiling of Kidney Biopsies Predict Delayed Graft Function

P. Rao,¹ D. Deo,¹ B. Fyfe-Kirschner,² R. Siderits.²
Histone Deacetylase Inhibition Mitigates Limb Ischemia Reperfusion Injury

S. Concors,¹ D. Aufhauser,¹ D. Murken,¹ Z. Wang,¹ G. Ge,¹ T. Bhatti,⁴ W. Hancock,^3,4 M. Levine.^1,2
Histone Deacetylase-6 Inhibition Mitigates Liver Ischemia-Reperfusion Injury and Acetaminophen Toxicity in Mice

S. Concors,¹ D. Murken,¹ D. Aufhauser,¹ Z. Wang,¹ G. Ge,¹ T. Bhatti,⁴ W. Hancock,^3,4 M. Levine.^1,2
HIV-Positive Donors to HIV-Positive Transplant Recipients: The Italian Experience

P. Grossi,¹ D. Dalla Gasperina,¹ A. Petrolo,¹ D. Lombardi,¹ M. Balsamo,¹ M. Moioli,² G. Travi,² M. Merli,² F. Ferla,² M. Tozzi,¹ L. De Carlis,² G. Carcano,¹ M. Puoti,² A. Nanni Costa.³
HIV, HBV, and HCV Screening with NAT and Serology in the OPO Setting

N. Theodoropoulos,¹ M. Ison.²
HLA Desensitization Using Rituximab/ Immunoadsorption before Kidney Transplantation

P. Malvezzi, T. Jouve, D. Masson, J. Maurizi, B. Bardy, P-.L. Carron, B. Janbon, N. Terrier, L. Rostaing.
HLA Eplet Mismatch and Donor Specific Antibodies in Kidney Transplantation

S. Wan,^1,2 S. Angel de Wilde,² B. Rosales,² S. Chadban,^1,2 K. Wyburn.^1,2
HLA Mismatching and cPRA Do Not Affect BK Viremia and Nephropathy Risk in Kidney Transplantation: A Retrospective Analysis

B. Suleiman, S. Saleh, W. Hassan, K. Wang, A. Maibam, A. Karim, A. Hines, X. Mei, A. El-Husseini, M. Yaseen, V. Cornea, A. Castellanos, R. Gedaly, T. Waid.
HLA Typing, Panel Reactive Antibody and Donor Specific Antigen Tests Are Not Necessary for Successful Parathyroid Allotransplantation

E. Kanimdan,¹ B. Goncu,² Y. Gelmez,³ O. Idiz,⁴ C. Toka,⁵ B. Ozdemir,² H. Basoglu,⁶ N. Ozten Kandas,⁷ E. Yucesan,⁸ Y. Ersoy,⁵ R. Kazancioglu,⁹ E. Aysen.⁵
HLA-DR4 Matching and Hepatocellular Carcinoma Recurrence after Liver Transplantation

M. Xu, S. Garcia-Aroz, N. Vachharajani, Y. Lin, W. Chapman.
HO-1 Regulates SIRT1– Autophagy Pathway in Liver Transplantation: From Mouse-to-Human

K. Nakamura,¹ S. Kageyama,¹ S. Yue,¹ A. Aziz,¹ T. Ito,¹ D. Oncel,¹ B. Ke,¹ R. Sosa,² E. Reed,² F. Kaldas,¹ R. Busuttil,¹ J. Kupiec-Weglinski.¹
HOPE Act Deceased Organ Donors: True and False Positive Donors

C. Durand,¹ S. Seaman,¹ M. Bowring,¹ B. Doby,¹ D. Ostrander,¹ A. Redd,¹ M. Waldram,¹ S. Huprikar,² B. Haydel,² S. Lerner,² S. Florman,² N. Turgeon,³ R. Friedman-Moraco,³ A. Massie,¹ D. Segev.¹
Hospital Readmission Patterns in the First Year after Kidney Transplantation: A Twelve-Year, Single-Center Experience

M. Nguyen, C. Avila, J. Benedict, A. El-Hinnawi, A. Rajab, R. Pelletier, M. Henry, G. Bumgardner.
Hospital Readmissions Following ABO-Incompatible Live Donor Kidney Transplantation: A National Study

B. Orandi,¹ X. Luo,² S. Bae,² E. King,² J. Garonzik-Wang,² D. Segev.²
Hospitality Houses and Transplant Patients: Assessing the Impact of a Hospitality House Dedicated to Transplant Patients and Their Families

T. Giordano,¹ J. Campbell,² J. Weinstock,³ H. Nathan.³
Hospitalization and Life Support before Liver Transplantation – Easily Available Predictors for Post-Transplant Patient Survival

L. Wiering, P. Ritschl, M. Hippler-Benscheidt, F. Aigner, M. Biebl, D. Eurich, M. Schmelzle, I. Sauer, K. Kotsch, J. Pratschke, R. Öllinger.
Hospitalization, Dialysis Center Type, and Disparities in ESRD Survival and Waitlist Access

R. Lynch, R. Zhang, A. Adams, R. Patzer.
Host Factors and Clinical Spectrum of Adenovirus Infection in Pediatric Solid Organ Transplantation: A Closer Look at the Infant, the Toddler and the Child

C. Del Valle Mojica, S. Chen, H. Gans.
How Early is Too Early for a Preemptive Kidney Transplant? A Markov Decision Process-Based Retrospective Analysis

M. Kurt,¹ A. Khojandi,² M. Barah,² B. Tanriover.³
How Evaluation for Living Kidney Donation Saved My Life

M. Guthoff,¹ T. Mühlbacher,¹ S. Nadalin,² N. Heyne.¹
How Old is Too Old? Expanding Living Kidney Organ Transplantation from Donors above 60 Years of Age with Associated Comorbidity.

A. Ghazanfar, L. Salih.
How Safe is Crossing the ABO Blood Group Barrier? A Meta-Analysis to Determine the Additive Risk of ABO-Incompatible Kidney Transplantation

A. de Weerd, M. Betjes.
How Safe is Immunosuppression Maintenance 1 Year after Renal Allograft Failure?

A. Mena-Gutierrez, K. Alquadan, A. Santos, K. Womer, M. Casey.
How Should Pancreas Transplant Rejection Be Treated?

F. Aziz, S. Parajuli, S. Salahuddin, K. Harrold, A. Djamali, B. Astor, J. Odorico, D. Mandelbrot.
How the Spouses (Husbands) of Living Kidney Donors View Kidney Donation: A Grounded Theory Study

J. Kieffer.
Hsp70 Inhibitor Could Induce Transplant Tolerance through mTORC2/Akt Pathway

G. Gu, T. Lu, N. Xu, Q. Xia.
Human Atrial Natriuretic Peptide (hANP) in Cold Storage of Donation after Cardiac Death Livers: A New Tool for Protecting Vascular Endothelia?

Y. Nigmet,¹ K. Hata,¹ Y. Okamura,¹ I. Tamaki,¹ T. Tsuruyama,² H. Hirao,¹ T. Kubota,¹ J. Kusakabe,¹ J. Yoshikawa,¹ T. Goto,¹ T. Tajima,¹ H. Tanaka,¹ S. Uemoto.¹
Human CD8⁺CD28^– T Cells Driven In Vitro by IL-15 Suppress in Allo-Specific Manner Partially through PD-1:PD-L1 Pathway

F. Feng,^1,2 G. Liu,¹ P. Zhu,¹ M. Zhu,¹ X. Lu,¹ J. Liu,² X. Luo,³ Y. Liu,¹ Y. Yu.²
Human CD8⁺CD28^– Ts Cells Expanded by Common Gamma Chain (γc) Cytokines Keep Steady Allospecific Suppressive Capacity In Vivo

G. Liu,¹ F. Feng,¹ P. Zhu,¹ J. Liu,² Y. Liu,¹ Y. Yu.²
Human Endothelial-Like Cells Transdifferentiated from Peripheral CD14⁺ Monocytes Inhibit T Cells in Response to Allo-Stimulation

Y. Tanaka, H. Ohdan.
Human Pancreatic ECM Scaffolds for Islet Culture and Transplantation

D. Tremmel, S. Sackett, A. Feeney, R. Maguire, J. Odorico.
Human Thrombomodulin Expression on Genetically Modified Donor Pigs is Required to Maintain the Anti-Coagulation Profile

A. Singh, L. DiChiacchio, J. Chan, P. Corcoran, B. Lewis, M. Thomas, D. Ayares, K. Horvath, M. Mohiuddin.
Human Urine-Derived Stem Cells Protect Renal Function by Releasing miR-129-5p Which Targets High-Mobility Group Box-1 (HMGB1) in Rat Ischemia Reperfusion Injury Model

L. Liu, X. Li, Q. Su, Z. Bi, H. Huang, C. Wang.
Humoral Immune Response to Seasonal Influenza Infection in Transplant Recipients

C. Hirzel,¹ V. Ferreira,¹ A. L'Huillier,¹ K. Hoschler,² E. Cordero,³ G. Reid,⁴ J. Englund,⁵ A. Limaye,⁶ A. Humar,¹ D. Kumar.¹
Humoral Immunity to CMV Remains Intact after Dual Targeting Desensitization in Allosensitized Nonhuman Primates

P. Schroder, B. Ezekian, F. Saccoccio, J. Yoon, M. Dennis, K. Freischlag, J. Kwun, S. Permar, S. Knechtle.
Hyaluronic Acid as Early Biomarker of Graft Loss after Liver Transplantation: A Prospective Study

A. Rostved,¹ S. Ostrowski,² L. Peters,³ J. Lundgren,³ C. Sørensen,¹ H-.C. Pommergaard,¹ J. Hillingsø,¹ A. Rasmussen.¹
Hyperglycemia Aggravates Hepatic Ischemia and Reperfusion Injury by Inhibiting Liver Resident Macrophage M2 Polarization via C/EBP-Homologous Protein-Mediated Endoplasmic Reticulum Stress

Z. Rao, J. Sun, X. Pan, Z. Chen, H. Sun, P. Zhang, M. Gao, Z. Ding, C. Liu.
Hyperglycemia-Triggered ATF6-CHOP Pathway Exacerbates Liver Ischemia/Reperfusion Injury: Immunomodulation by Regulating β-Catenin Signaling

J. Rao,^1,2 C. Yang,¹ Y. Hu,¹ S. Yang,¹ Y. Xia,¹ F. Zhang,¹ X. Wang,¹ Y. Zhai,² L. Lu.^1,2
Hyperglycemia-Triggered S1P/SIPR3signaling Exacerbates Liver Ischemia/Reperfusion Injury by Regulating M1/M2 Polarization

J. Rao,^1,2 Y. Hu,¹ C. Yang,¹ S. Yang,¹ F. Cheng,¹ F. Zhang,¹ X. Wang,¹ Y. Zhai,^1,2 L. Lu.^1,2
Hyperkalemia in the Early Post Renal Transplant Period

E. Christie, J. Okel, M. Gowrishankar.
Hypothermic Machine Perfusion Protects DCD Liver Graft through Metabolism of Xenobiotics by Cytochrome P450 Pathway

Q. Ye,^1,2 W. Liang,¹ Z. Zhong,¹ S. Ye,¹ B. Tang,¹ Q. Hu,¹ J. Liang,¹ Y. Wang.¹
Hypothermic Machine Perfusion Protects Rabbit Kidney Graft through Down Regulation SPP1-MMP7 Signaling Axis

Q. Hu,¹ Z. Zhong,¹ S. Xue,¹ W. Liang,¹ J. Lan,¹ J. Liang,¹ Y. Xiong,¹ Y. Wang,¹ Q. Ye.^1,2
Hypothermic Oxygenated Machine Perfusion in Liver and Kidney Transplantation of Extended Criteria Donors: A Phase-1 of Clinical Trial

M. Ravaioli,¹ V. De Pace,¹ M. Cescon,¹ M. Del Gaudio,¹ V. R. Bertuzzo,¹ A. Siniscalchi,¹ A. D'Errico,² G. Comai,² G. La Manna,² A. D. Pinna.¹
Hypoxia Results in Endoplasmic Reticulum Stress and Activation of the Unfolded Protein Response in Isolated Human Islets and Human Donor Pancreases

B. Sandhu, M. Prendecki, N. Vallant, G. Rutter, C. Pusey, V. Papalois.

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