Am J Transplant, Volume 16, Suppl 3 Archives - Page 80 of 180 - ATC Abstracts

2016 American Transplant Congress
Increased Access to Transplantation of Highly Sensitized Patients Facilitated by the New Kidney Allocation System.
A. Colovai, M. Ajaimy, C. Savchik, S. Chan, P. Masiakos, J. Rocca, E. Akalin.
Abdominal Transplant, Montefiore Medical Center, Bronx, NY.
The purpose of our study was to evaluate the impact of the new kidney allocation system (KAS 2014) on the access to transplantation of HLA…
2016 American Transplant Congress
Molecular Assessment of Kidney Transplant Biopsies Performs Similarly in Medulla and Cortex.
K. Madill-Thomsen,¹ J. Reeve,¹ G. Bohmig,² F. Eskandary,² P. Halloran.^1,3
¹Alberta Transplant Applied Genomics Center, Edmonton, AB, Canada; ²Department of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria; ³Department of Medicine, Division of Nephrology and Transplant Immunology, University of Alberta, Edmonton, AB, Canada.
Histologic assessment of kidney biopsies is usually unable to interpret medulla, but molecular changes associated with rejection likely occur in both medulla and cortex. Analysis…
2016 American Transplant Congress
Pre-Transplant Panel of Reactive T Cells (PRT) as an Independent Predictor of 2-Year Kidney Graft Function.
I. Gandolfini,¹ E. Crespo,² M. Baweja,¹ U. Maggiore,³ P. Cravedi,¹ P. Heeger,¹ O. Bestard.²
¹Icahn School of Medicine, New York, NY; ²Bellvitge University Hospital, Barcelona, Spain; ³University of Parma, Parma, Italy.
Background: The ELISPOT PRT quantifies frequencies of IFN-g-producing effector/memory T cells reactive against a panel of allogenic stimulators. In contrast to the donor-reactive ELISPOT, it…
2016 American Transplant Congress
Global Kidney Exchange.
M. Rees,¹ T. Dunn,¹ S. Rees,¹ J. Rogers,¹ L. Reece,¹ A. Roth,² C. Kuhr,¹ O. Ekwenna,¹ D. Fumo,¹ K. Krawiec,³ S. Jain,¹ C. Marsh,¹ M. Tan,¹ S. Paloyo.⁴
¹Alliance for Paired Kidney Donation, Perrysburg; ²Stanford University, Palo Alto; ³Duke University, Durham; ⁴Philippine General Hospital, Manila, Philippines.
Introduction: Instead of thinking of the developing world as a place where there are desperate people who will sell their kidneys for money, we propose…
2016 American Transplant Congress
Predictors of Postoperative Cardiovascular Complications Until Three Months After Kidney Transplantation.
M. Slot,^1,2 J. van de Wetering,¹ M. Kho,¹ M. Betjes,¹ J. Roodnat.¹
¹Nephrology, Erasmus Medical Center, Rotterdam, Netherlands; ²Nephrology, VU Medical Center, Amsterdam, Netherlands.
Purpose: To identify factors involved in cardiac events within three months after renal transplantation.Methods: We conducted a chart review for all renal transplants (RT) performed…
2016 American Transplant Congress
Simulating Alternative Bayesian Criteria to Identify Transplant Center Performance Outliers.
J. Schold,¹ C. Miller,¹ M. Henry,² L. Buccini,¹ S. Flechner,¹ D. Goldfarb,¹ E. Poggio,¹ K. Andreoni.³
¹Cleveland Clinic, Cleveland, OH; ²Ohio State University, Columbus, OH; ³University of Florida, Gainesville, FL.
The newly constructed Bayesian models to evaluate transplant center performance were implemented in 2014. The rates and impact of the assumptions used for flagging centers…
2016 American Transplant Congress
Renal Fibroblast Activation and Survival by Anti-MHC Class I Antibody: The Role of mTOR Signaling Pathway.
J. Chen, A. Zmijewska, R. Mannon.
Medicine/Surgery, University of Alabama at Birmingham, Birmingham, AL.
Background: Antibody-mediated injury (AMI) is an important contributor to late kidney allograft loss, and is accompanied by interstitial fibrosis (IF) and tubular atrophy (TA). However,…
2016 American Transplant Congress
A Unique In Vitro Migration Model for Leukocyte Trans-Lymphatic Endothelial Migration.
Y. Xiong,¹ C. Brinkman,¹ K. Hippen,² B. Blazar,² J. Bromberg.¹
¹University of Maryland, Baltimore; ²University of Minnesota, Minneapolis.
Trans-endothelial migration (TEM) is an essential process for leukocyte circulation. While much is known about lymphocyte blood to tissue migration, far less is known about…
2016 American Transplant Congress
Mechanism of FK506 Induced TNF Related Apoptosis in Jurkat T Cells.
S. Chung, S. Choi.
Department of Surgery, Chonnam National University Hospital, Gwangju, Korea.
Purpose: To elucidate the mechanism of FK506 induced TRAIL(TNF related apoptosis inducing ligand) –R1(DR4) and TRAIL-R2(DR5) in FK506-treated Jurkat T cells. And signal transduction pathway…
2016 American Transplant Congress
Is Delayed Graft Function in Simultaneous Kidney-Pancreas Transplant Recipients Associated with an Increased Risk of Pancreas Graft Failure?
S. Singh,^1,2 S. Kim.^1,2,3,4
¹Division of Nephrology, Department of Medicine, University of Toronto, Toronto, Canada; ²Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada; ³Division of Nephrology and the Multi-Organ Transplant Program, University Health Network, Toronto General Hospital, Toronto, Canada; ⁴Division of Nephrology and the Kidney Transplant Program, St. Michael's Hospital, Toronto, Canada.
Background: Delayed graft function (DGF) in kidney transplant recipients is associated with adverse short and long-term outcomes. However, the impact of DGF of the kidney…