2016 American Transplant Congress
Short Term Changes in HRQOL Following Kidney Transplantation.
Health-Related Quality of Life (HRQOL) is a patient-centered outcome that measures the impact of a disease and its treatment. This is particularly relevant to those…2016 American Transplant Congress
Everolimus Plus Reduced-Exposure Cyclosporin versus Mycophenolic Acid Plus Cyclosporin: Seven-Year Follow-Up of Australia and New Zealand Kidney Transplant Recipients in the A2309 Study.
A2309 was a 2-year, phase III randomized controlled trial evaluating the effect on graft and patient outcomes of three groups:1.5mg everolimus plus low exposure cyclosporine…2016 American Transplant Congress
Better Never Than Late: Differences in Outcomes and Risk Factors for Early and Late Rejection After Kidney Transplantation.
Medicine, University Hospitals Case Medical Center, Cleveland, OH.
Background: Late acute rejection (AR) is associated with inferior outcomes relative to early AR after kidney transplantation. We sought to examine the differences in risk…2016 American Transplant Congress
Fc Receptor Binding Assay for Functional Assessment of HLA Antibodies: Initial Clinical Validation.
Functional assessment of HLA antibodies (Abs) has historically been limited to complement-based assays, which have known limitations. Moreover, HLA Abs mediate injury by complement-independent mechanisms,…2016 American Transplant Congress
Immunogenic HLA-DR Eplet Mismatches as Predictors of Transplant Glomerulopathy.
BackgroundThe number of HLA-DR eplet mismatches (eplet load) is a risk factor for the development of anti-HLA antibodies and transplant glomerulopathy (TG). In the case…2016 American Transplant Congress
Reversibility of Acute Kidney Rejection According to the Banff 2013 Classification: A Retrospective Cohort Study.
1CRCHUM, Montreal, QC, Canada; 2Statsciences, Montreal, QC, Canada; 3HMR, Montreal, QC, Canada.
Background: Vascular involvement of the allograft has classically been regarded as a poor prognostic factor in acute kidney graft rejection. Cell-mediated endarteritis often coexists with…2016 American Transplant Congress
YKL-40 Predicts Renal Recovery in Deceased-Donor Transplantation.
Background Deceased-donor kidneys with acute kidney injury (AKI) are often discarded for fear of poor transplantation outcomes. Donor biomarkers that predict post-transplant renal recovery could…2016 American Transplant Congress
Analysis of Local versus Imported Expanded Criteria Donor (ECD) Kidneys: A Single Center Experience with 497 ECD Kidney Transplants.
With the new Kidney Allocation System, broader sharing of expanded criteria donor (ECD) kidneys may occur, which may influence discard rates and survival outcomes. To…2016 American Transplant Congress
Regression of Asymptomatic Cardiomyopathy and Clinical Outcome of Renal Transplant Recipients: Long-Term Extension of Two Randomized Controlled Trials.
Nephrology, Dialysis, and Transplantation, University of Genoa, Genoa, Italy.
Background Asymptomatic left ventricular hypertrophy (LVH) is highly prevalent and associated with adverse outcome in renal transplant recipients (RTRs). Nonetheless, there are currently no available…2016 American Transplant Congress
Heparanase: A New Factor Involved in the Pro-Fibrotic Renal Biological Machinery Activated by the Ischemia/Reperfusion (I/R) Injury.
Ischemia/reperfusion (I/R) is an important cause of acute renal failure and delayed graft function, and it may induce chronic renal damage by activating epithelial to…
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