ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Safety of a Short (One-Year) Waiting Time in Kidney Transplant Candidates Treated for Cancer.

D. Dahle,1 T. Grotmol,2 T. Leivestad,3 A. Hartmann,1 G. Mjøen,1 H. Pihlstrøm,1 H. Næss,1 H. Holdaas.1

1Department of Transplant Medicine, Oslo University Hospital, Oslo, Norway
2The Cancer Registry of Norway, Oslo, Norway
3Norwegian Renal Registry, Oslo University Hospital, Oslo, Norway.

Meeting: 2016 American Transplant Congress

Abstract number: 159

Keywords: Kidney transplantation, Malignancy

Session Information

Date: Sunday, June 12, 2016

Session Name: Concurrent Session: Older and High Risk Kidney Transplant Recipients/Donors

Session Time: 4:30pm-6:00pm

 Presentation Time: 5:42pm-5:54pm

Location: Ballroom A

Related Abstracts
  • Pre-Transplant Prostate Cancer in Lung Transplant Recipients and Impact on Post-Transplant Morbidity and Mortality.
  • Outcome of Adult Kidney Transplant Candidates With Previous Malignancy: Analysis of 14-Year Waiting List Data in the United States

In Norway, a one-year waiting time free of cancer recurrence is required before kidney transplantation. To provide an updated, large-scale assessment of this practice, the survival of such a group of patients was compared to that of a matched cohort of kidney transplant recipients (KTRs) without a history of pretransplant cancer.

Methods: KTRs with pretransplant cancer were identified in the Cancer Registry. Combined organ transplantations were excluded. Basal cell carcinoma was not uniformly registered and excluded as cancer diagnosis. No waiting time was required for localized prostate cancer, but this diagnosis was also included. A control group of KTRs without pretransplant cancer was constructed by coarsened exact matching in Stata, with age, gender and transplant era (<1983, 1983-1999, >2000) as matching variables. Follow-up was censored by November 2013, and survival compared by Kaplan-Meier plot and Cox regression.

Results: From 1963 to 2010, 5622 KTRs were included, of whom 361 had a history of pretransplant cancer. The median follow-up (interquartile range) was 6.2 (0.3-11.5) years. 2980 patients died, 30/361 (8.3%) of a cancer recurrence, of whom 6/103 of renal cancer, 5/43 prostate, 4/35 colorectal, 5/40 urothelial, 1/26 breast, 3/20 melanoma, 1/6 lung, 0/11 Non-Hodgkin lymphoma, 1/3 Hodgkin lymphoma, 3/15 plasma cell neoplasia, 0/10 cervix, and 1/1 acute myeloid leukemia. Patient survival in KTRs with a history of pretransplant cancer was similar to that of controls (Figure), hazard ratio (HR) 1.06 (95% CI 0.93-1.22), p=0.39. Defining waiting time from diagnosis of cancer to transplantation, there was no increased risk after stratifying for waiting times: 0-1 year (n=34; HR 1.03 [0.69-1.54], p=0.90), 1-2 years (n=49; HR 0.93 [0.63-1.39], p=0.74), 2-5 years (n=116; HR 1.14 [0.90-1.44], p=0.26) or >5 years (n=162; HR=1.07 [0.87-1.32], p=0.52).

Conclusion: A short (one year) waiting time after cancer was not associated with increased mortality in KTRs.

CITATION INFORMATION: Dahle D, Grotmol T, Leivestad T, Hartmann A, Mjøen G, Pihlstrøm H, Næss H, Holdaas H. Safety of a Short (One-Year) Waiting Time in Kidney Transplant Candidates Treated for Cancer. Am J Transplant. 2016;16 (suppl 3).

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Dahle D, Grotmol T, Leivestad T, Hartmann A, Mjøen G, Pihlstrøm H, Næss H, Holdaas H. Safety of a Short (One-Year) Waiting Time in Kidney Transplant Candidates Treated for Cancer. [abstract]. Am J Transplant. 2016; 16 (suppl 3). https://atcmeetingabstracts.com/abstract/safety-of-a-short-one-year-waiting-time-in-kidney-transplant-candidates-treated-for-cancer/. Accessed March 4, 2021.

« Back to 2016 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Penis Transplantation: First U.S. Experience.
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Penis Transplantation: First U.S. Experience.
  • A Decade of Donor-Derived Disease: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Evidence of a Clinically Significant Drug-Drug Interaction between Cannabidiol and Tacrolimus: A Case Report
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.