ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Belatacept Conversion in Adult Kidney Transplant Recipients for Cause: A Single Center Observational Cohort.

    M. Savic,1 M. Cruz,2 A. Rossi,1 J. Vella.1

    1Maine Transplant Program, Maine Medical Center, Portland, ME; 2University of Connecticut, Storrs, CT.

    Background: Calcineurin inhibition (CNI) is the single most effective strategy to prevent allograft rejection however tolerability is limited by toxicity. To date, alternate strategies have…
  • 2016 American Transplant Congress

    Donor-Specific Antibodies in a Single-Center Pediatric Kidney Transplant Population – Incidence and Risk Factors.

    M. Bock,1 L. Starkey,1 C. Buchanan,2 E. Steinberg,2 A. Sikora,2 K. McKinnon,2 M. Wachs,2 J. Goebel.1

    1Transplant Surgery, Children's Hospital Colorado, Aurora, CO; 2Pediatric Nephrology, Children's Hospital Colorado, Aurora, CO.

    In mid-2015, we implemented donor-specific antibody (DSA) monitoring in our pediatric kidney transplant recipient (pKTR) population as recommended (Transplantation 2013;95:19-). We now cross-sectionally analyzed our…
  • 2016 American Transplant Congress

    A Retrospective Analysis of Rabbit Antithymocyte Globulin Dosing, MELD, Race, and Weight on Infection and Rejection Rates in Liver Transplantation.

    R. Imai, U. Wang.

    Department of Pharmacy, Stanford Health Care, Stanford, CA.

    INTRODUCTION: Rabbit antithymocyte globulin (rATG) use in liver transplantation is uncommon. At our center, induction therapy is comprised of rATG dosed at 1 – 2…
  • 2016 American Transplant Congress

    Ideal Outcome After Liver Transplantation: An Exploratory Study Using Machine Learning Analyses to Leverage Long-Term Registry Data from Studies in Pediatric Liver Transplantation (SPLIT).

    E. Hsu,1 M. Shaffer,1,2 R. Anand,3 V. Ng,4 J. Bucuvalas.5

    1University of Washington School of Medicine, Seattle, WA; 2Children's Core for Biomedical Statistics, Center for Clinical and Translational Research, Seattle Children's Hospital, Seattle, WA; 3The EMMES Corporation, Rockville, MD; 4The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada; 5Cincinnati Children's Hospital and Medical Center, Cincinnati, OH.

    We analyzed the Studies in Pediatric Liver Transplantation (SPLIT) registry dataset using heat map and random forests analyses (RFA) to determine if ideal outcome (IO)…
  • 2016 American Transplant Congress

    Liver Transplantation for Propionic Acidemia: A Review of the United States Scientific Registry for Transplant Recipients (SRTR) and Non-US Case Series.

    N. Celik, K. Soltys, G. Bond, Q. Sun, G. Vockley, R. Sindhi, G. Mazariegos.

    Surgery, Childrens Hospital of Pgh, Pittsburgh.

    Background: A fifth of all pediatric liver transplants in the US are performed for metabolic disease. Propionic acidemia, an autosomal recessive branched chain organic acidemia…
  • 2016 American Transplant Congress

    Increased Gene Expression of TGF-β in Peripheral Blood Mononuclear Cells from Renal Transplant Patients with Polyomavirus BK Viremi.

    W. Yin,1 M. Lu.2

    1Surgery, School of Medicine, Tzu Chi University, Hualien, Taiwan, Division of General Surgery, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chia-I, Dalin, Taiwan; 2Allergy, Immunology and Rheumatology, School of Medicine, Tzu Chi University, Hualien, Taiwan, Division of Allergy, Immunology and Rheumatology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chia-I, Dalin, Taiwan.

    We aimed to investigate the roles of cytokines during polyomavirus BK (BKV) reactivation in renal transplant patients. Forty-eight renal allograft recipients were enrolled in this…
  • 2016 American Transplant Congress

    Thrombotic Microangiopathy After Kidney Transplantation: A Rare but Serious Complication.

    C. Teixeira, I. Pietrobom, A. Lima, N. Tenório, G. Basso, M. Cristelli, L. Viana, G. Kirsztajn, H. Tedesco-Silva, J. Medina-Pestana.

    Universidade Federal de São Paulo, São Paulo, Brazil.

    Purposes: Study the clinical characteristics of cases with thrombotic microangiopathy (TMA) in the renal allograft, identify the triggers of this disease and determine its impact…
  • 2016 American Transplant Congress

    Angiotensin II Blockade and Fibroblast Growth Factor-23 in Stable Kidney Transplant Recipients.

    O. Sanchez, S. Reule, S. Li, D. Berglund, R. Spong, H. Ibrahim.

    U of MN, Mpls.

    Introduction: FGF-23 has been linked to allograft failure. However, careful serial profiling of FGF-23 has not been done. Therefore, we measured FGF-23 levels in recipients…
  • 2016 American Transplant Congress

    Outcomes from De Novo Tacrolimus Weight-Based Dosing Compared to Conservative Dosing in Kidney Transplant Recipients.

    B. Summers,2 K. Szempruch,1 M. Harris,2 A. Quidley,1 C. Haisch,1 A. Maldonado.1

    1Vidant Medical Center/East Carolina University, Greenville, NC; 2Duke University Hospital, Durham, NC.

    Purpose: To compare de novo tacrolimus (TAC) weight based dosing (WDG) and conservative dosing (CDG) on incidence and duration of DGF in adult kidney transplant…
  • 2016 American Transplant Congress

    Direct-Acting Antivirals for Hepatitis C Treatment in Kidney Transplant Recipients.

    N. Goyal, W. Huepfel, A. Tierney, N. Issa, J. Lake, J. Thompson, M. Hassan, H. Ibrahim, A. Kukla.

    University of Minnesota, Minneapolis.

    Background: Hepatitis C infection is associated with worse clinical outcomes in kidney transplant recipients. Direct-acting antivirals (DAAs) have been effectively used in liver transplant patients…
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