ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Differential Effect of Delayed Graft Function (DGF) on Kidney Transplant Outcomes: When Does DGF Not Make a Difference?

    M. Khan,1 H. El-Hennawy,1 A. Farney,1 J. Rogers,1 G. Orlando,1 A. Reeves-Daniel,2 A. Palanisamy,2 M. Gautreaux,3 S. Iskandar,3 W. Doares,4 S. Kaczmorski,4 R. Stratta.1

    1Surgery, Wake Forest, Winston-Salem, NC; 2Internal Medicine, Wake Forest, Winston-Salem, NC; 3Pathology, Wake Forest, Winston-Salem, NC; 4Pharmacy, Wake Forest, Winston-Salem, NC.

    Delayed graft function (DGF), defined as need for dialysis in 1st week following kidney transplant (KT), is an early surrogate marker of organ quality and…
  • 2016 American Transplant Congress

    Preservation of Alloreactive and Antiviral Immunity After Switch to Belatacept-Based Regimen After Kidney Transplantation.

    J. Schaenman,1 Y. Korin,2 T. Sidwell,2 V. Groysberg,2 J. Gadzhyan,1 E. Lum,1 U. Reddy,1 E. Huang,1 T. Pham,1 G. Danovitch,1 E. Reed,2 S. Bunnapradist.1

    1Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA; 2Department of Pathology, David Geffen School of Medicine at UCLA, Los Angeles, CA.

    Purpose: We set out to investigate the impact of switch from calcineurin inhibitor (CNI) to belatacept on T cell mediated allo- and EBV-specific immunity.Methods: We…
  • 2016 American Transplant Congress

    Unexpected Early Calcineurin Inhibitor Nephrotoxicity in Pediatric Kidney Transplant Recipients.

    M. Yanik,1 R. Mannon,2 M. Seifert.1

    1Pediatrics, University of Alabama at Birmingham, Birmingham, AL; 2Medicine, University of Alabama at Birmingham, Birmingham, AL.

    Background: Calcineurin inhibitors effectively suppress the recipient immune response and facilitate early success in kidney transplantation. However, these drugs are potent nephrotoxins and contribute to…
  • 2016 American Transplant Congress

    Early Tacrolimus Exposure in Patients Treated De Novo with Once-Daily Tacrolimus After Liver Transplantation: Relationship with Acute Rejection and Long-Term Outcome.

    M. Gastaca, A. Valdivieso, J. Bustamante, P. Ruiz, J. Fernandez, A. Ventoso, M. Testillano, I. Palomares, M. Prieto, P. Salvador, A. Matarranz, M. Suarez, J. Ortiz de Urbina.

    Liver Transplantation Unit, Cruces University Hospital, Bilbao, Vizcaya, Spain.

    AIM: The aim of our study was to define the possible influence of early tacrolimus exposure on long-term outcomes in patients treated with de novo…
  • 2016 American Transplant Congress

    Cost-Effectiveness of Machine Perfusion Use After Long Cold Ischemic Time in a Kidney Transplantation Program.

    A. Matos, D. Malheiros, S. Morgado, L. Requiao-Moura, M. Borrelli, M. Nogueira, M. Durao, E. Tonato, A. Pacheco-Silva.

    Renal Transplantation Unit, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.

    In Brazil the incidence of DGF is very high (60-70%) mainly due to an inadequate care of the donors and long cold ischemia time. This…
  • 2016 American Transplant Congress

    Long-Term vs Short-Term Valganciclovir Prophylaxis Use for Cytomegalovirus and Epstein-Barr Virus Infections in Pediatric Living Related Liver Transplantation.

    T. Ueno,1 H. Yamanaka,1 Y. Takama,1 N. Tanaka,1 Y. Tazuke,1 K. Bessho,2 H. Okuyama.1

    1Pediatric Surgery, Osaka University Graduate School of Medicine, Suita, Japan; 2Pediatrics, Osaka University Graduate School of Medicine, Suita, Japan.

    [Purpose] Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) infections are the most important viral infections in pediatric patients with transplant. Valganciclovir (VGCV) has been used as…
  • 2016 American Transplant Congress

    Incidence and Factors Associated with De Novo DSA After BK Viremia in Renal Transplant Recipients.

    S. Patel, S. Kuten, R. Knight, D. Nguyen, E. Graviss, A. Gaber.

    Houston Methodist Hospital, Houston, TX.

    Recent literature indicates an elevated rate of de novo DSA (dnDSA) following BK viremia (BKV) in renal transplant recipients (RTR). We sought to review our…
  • 2016 American Transplant Congress

    Graft Loss Due to Recurrence of Focal Segmental Glomerulosclerosis in Second Renal Transplant.

    V. Aggarwal, A. Gruessner, R. Gruessner, V. Whittaker, S. Narsipur.

    Transplant, Upstate Medical University, Syracuse, NY.

    Introduction : Focal segmental glomerular sclerosis (FSGS) glomerulonephritis can recur in renal transplants, and can potentially lead to graft loss. The rate of graft loss…
  • 2016 American Transplant Congress

    Give One and Done? Evaluating a Change in Surgical Prophylaxis in Kidney Transplant Recipients.

    K. Bliven, C. Truax, K. Snow, N. Kenyon, A. Carlson, S. Yeager, L. Smith.

    Pharmacy, University of Utah Hospital and Clinics, Salt Lake City, UT.

    Surgical-site infections (SSIs) occur in up to 11% of kidney transplant (txp) patients (pts). There is no consensus on the optimal peri-op prophylaxis regimen for…
  • 2016 American Transplant Congress

    Mycophenolate Mofetil Dose Reduction Are Associated with the Risk of Acute Rejection and Graft Failure After Renal Transplantation.

    A. El-Agroudy,1 A. Taher,2 A. Alaradi,2 B. Alhayki,2 S. Gareeb,2 E. Farid.2

    1Internal Medicine, College of Medicine, Arabian Gulf University, Manama, Bahrain; 2Nephrology, Salmaniya Medical Complex, Manama, Bahrain.

    Background: Mycophenolate mofetil (MMF) is a highly effective immunosuppressive agent in transplant therapy. Although MMF is generally well tolerated, optimal therapy may be limited by…
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