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American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Early Posttransplant Complications Following Abo-Incompatible Kidney Transplantation.

    L. Rostaing,1,2,3 A. Allal,1 H. Naciri Benami,1 Z. Abdulrahman,1 L. Esposito,1 F. Sallusto,1 N. Doumerc,1 X. Game,1 B. Debiol,1 N. Congy,1 N. Kamar.1,3,4

    1Néphrologie et Transplantation d'Organes, CHU Rangueil, Toulouse, France; 2INSERM U 563, CHU Purpan, Toulouse, France; 3Faculté de Médecine de Rangueil, Université Toulouse III Paul Sabatier, Toulouse, France; 4INSERM U1043 CNRS UMR 5282, CHU Purpan, Toulouse, France.

    Introduction: Many studies or registries particularly in Japan, but also in Western Europe, have shown that long-term results from ABO-incompatible (ABOi) living-kidney transplantation are as…
  • 2016 American Transplant Congress

    Watch Out for the Guy with the Low EPTS Score: Nonadherence and Kidney Allograft Failure.

    A. Liu, K. Balabhadrapatruni, J. Augustine.

    Medicine, University Hospitals Case Medical School, Cleveland, OH.

    Background: Nonadherence is a known cause of rejection and kidney allograft failure. Our aim was to define risk factors for allograft loss related to nonadherence.…
  • 2016 American Transplant Congress

    Surgical Techniques in Modified Multiorgan Transplantation.

    W. Ju, J. Lin, J. Zhou, M. Chen, A. Yang, D. Wang, Y. Ma, Z. Guo, M. Han, X. Wang, X. Zhu, X. He.

    Organ Transplantation Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

    Objective: Investigate the clinical efficacy of combined en-bloc liver-pancreas transplantation in patients with end stage liver disease and diabetes.Method: The clinical data of 19 cases…
  • 2016 American Transplant Congress

    Profiling of T Cell Subsets in a Primate Cardiac Transplant Model.

    N. O'Neill, T. Zhang, G. Braileanu, W. Sun, X. Cheng, C. Evans, R. Pierson, A. Azimzadeh.

    Surgery, University of Maryland, Baltimore, MD.

    Purpose: Costimulation blockade prolongs graft survival but does not induce tolerance in primates, and mechanisms of rejection are incompletely understood. Here we evaluate changes in…
  • 2016 American Transplant Congress

    Indefinite Survival of Fully MHC-Mismatched Murine Cardiac Allografts by Combination of Anti-BTLA mAb (6B2) and Anti-PD-1 mAb (PIM-2).

    E. Yin,1,2 M. Uchiyama,1,3 X. Jin,1,4 T. Shimokawa,3 H. Yagita,5 M. Niimi.1

    1Surgery, Teikyo University, Tokyo, Japan; 2Cardiovascular Surgery, The 2nd Affiliated Hospital of Harbin Medical University, Harbin, China; 3Cardiovascular Surgery, Teikyo University, Tokyo, Japan; 4Thoracic Surgery, The 3rd Affiliated Hospital of Harbin Medical University, Harbin, China; 5Immunology, Juntendo University Hospital, Tokyo, Japan.

    Background: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA) and Programmed death (PD)-1 had been suggested to have immunomodulatory activity. This study investigated the…
  • 2016 American Transplant Congress

    Porcine Islets Engineered with SA-FasL Protein Induces Robust Tolerance in Mice through CD4+CD25+FoxP3+ Treg Cells.

    K. Woodward,1 H. Zhao,1 H. Shirwan,1 F. Wang,1 M. Graham,2 B. Hering,2 E. Yolcu.1

    1Institute for Cellular Therapeutics and Department of Microbiology and Immunology, University of Louisville, Louisville, KY; 2Schulze Diabetes Institute and Department of Surgery, University of Minnesota, Minneapolis, MN.

    Introduction: We have shown that porcine islets engineered to transiently display SA-FasL protein on their surface establish tolerance in mice following transplantation under the kidney…
  • 2016 American Transplant Congress

    The Impact of Non-Adherence on Disparities in African-American Kidney Transplant Recipients.

    D. Taber, A. Chokkalingam, A. Posadas, R. Browning, N. Salazar, M. Kamel, R. Pullalarevu, B. Kadri, T. Srinivas, K. Chavin, P. Baliga.

    MUSC, Charleston, SC.

    Background: Non-adherence is considered to a be a strong risk factor for graft loss in kidney transplant recipients, with conflicting evidence of its impact on…
  • 2016 American Transplant Congress

    Predicting Survival to Listing for Liver Transplantation: Do MELD and Race Interact?

    M. Jesse, E. Goldstein, N. Rebhan, C.-X. Ho, T. Macaulay, M. Bebanic, L. Shkokani, D. Moonka, M. Abouljoud, A. Yoshida.

    Transplant Institute, Henry Ford Health System, Detroit.

    Minimal research has been focused on the evaluation process for liver transplant listing. The purpose of this study was to examine whether evaluation MELD score…
  • 2016 American Transplant Congress

    Effect of Modifying Life Support Withdrawal Practices on Outcomes of Donation After Circulatory Death in Liver Transplantation: A Meta-Analysis.

    Y. Cao,1,2 S. Shahrestani,3 H. Chew,2,4 M. Crawford,5 P. Macdonald,1,2,4 J. Laurence,3,5,7 W. Hawthorne,3,6 K. Dhital,1,2,4 H. Pleass.3,5,6

    1Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia; 2Victor Chang Cardiac Research Institute, Sydney, NSW, Australia; 3Sydney Medical School, University of Sydney, Sydney, NSW, Australia; 4Cardiac Transplant Unit, St. Vincent's Hospital, Sydney, NSW, Australia; 5Australian National Liver Transplant Unit, Royal Prince Alfred Hospital, Sydney, NSW, Australia; 6The Department of Surgery, Westmead Hospital, Sydney, NSW, Australia; 7Institute of Academic Surgery, Royal Prince Alfred Hospital, Sydney, NSW, Australia.

    Aim. Donor warm ischaemic time is identified as the main risk factor for poor outcomes in liver transplantation using donation after circulatory death (DCD) compared…
  • 2016 American Transplant Congress

    Quadruple Induction Regimen with Basiliximab, Everolimus, Mycophenolate and Very Low Dose Tacrolimus Improves Graft Function without Increase in the Incidence of Microvascular Inflammation or De Novo Donor Specific Antibody Compared to the Standard Triple Regimen.

    M. Miura, H. Higashiyama.

    Department of Urology and Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.

    Objectives: Nephrotoxicity of calcineurin inhibitors (CNI) in kidney allografts has been a significant problem even with low exposure regimens. On the other hand, CNI-free regimen…
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