ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Improved Health Related Quality of Life Also in Older Recipients Following Kidney Transplantation.

    K. Lønning,1 K. Heldal,2,3 T. Bernklev,2,3 M. Andersen,1,4 A. Hartmann,1,3 N. Von der Lippe,3 A. Reisæter,1 K. Midtvedt.1

    1Department of Organ Transplantation, Oslo University Hospital, Oslo, Norway; 2Clinic of Internal Medicine, Telemark Hospital, Skien, Norway; 3Institute of Clinical Medicine, University of Oslo, Oslo, Norway; 4Department of Health Sciences, University of Oslo, Oslo, Norway.

    Background: There is a lack of knowledge regarding elderly patients with end stage renal disease (ESRD) and health related quality of life (HRQOL) after KTX.…
  • 2016 American Transplant Congress

    Early Steroid Withdrawal in African American Kidney Transplant Recipients: A Propensity Score Matching Analysis.

    D. Taber, M. Gebregziabher, T. Srinivas, K. Chavin, P. Baliga, L. Egede.

    MUSC, Charleston, SC.

    Objective: The aim of this study was to assess the safety of steroid withdrawal in African American (AA) kidney transplant (KTX) recipients.Methods: Longitudinal cohort study…
  • 2016 American Transplant Congress

    Dynamics of Delayed Graft Function-Associated Risk in Deceased Donor Kidney Transplantation.

    C. Liao, A. Massie, S. Bae, A. Muzaale, D. Segev.

    JHU, Baltimore.

    The long-term implications of delayed graft function (DGF) remain controversial. Moreover, non-proportional hazards of DGF have been reported in previous studies, which suggested that its…
  • 2016 American Transplant Congress

    Relationship Between Mean Fluorescence Intensity and C1q/C3d-Fixing Capacities of Anti-HLA Antibodies.

    G. Claisse,1 L. Absi,2 E. Alamartine,1 N. Maillard,1 C. Mariat.1

    1Centre Hospitalier Universitaire - Hôpital Nord, Saint-Etienne, France; 2Laboratoire EFS Loire-Auvergne, Saint-Etienne, France.

    The capacity of anti-HLA antibodies (Abs) to activate complement is thought to be an informative property susceptible to facilitate outcome prediction. Two different tests, C1q-…
  • 2016 American Transplant Congress

    DSA After Transplant Increases Risk of Renal Allograft Failure Independent of Concurrent Biopsy Results: The DEKAF Study Data.

    J. Cecka,1 J. Grande,2 F. Cosio,2 R. Leduc,3 The DeKAF Study Group.

    1UCLA Immunogenetics Center Department of Pathology, University of California-Los Angeles, Los Angeles, CA; 2Department of Lab Medicine & Pathology, Mayo Clinic College of Medicine, Rochester, MN; 3Department of Biostatistiscs, University of Minnesota School of Public Health, Minneapolis, MN.

    Donor-specific HLA antibodies (DSA) are a major cause of renal allograft dysfunction and loss following transplant. The presence of DSA, with or without C4d deposition,…
  • 2016 American Transplant Congress

    The Effect of Donor Age on Acute Rejection Age – The Clinical Impact of Donor Immuno-Senescence in the Modern Immunosuppressive Era.

    U. Khalid, P. Donato, L. Szabo, R. Chavez, E. Ablorsu, A. Asderakis.

    Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom.

    Experimental work has shown that donor age may alter the immune response of the recipient so that older donor grafts elicit a stronger response in…
  • 2016 American Transplant Congress

    IFTA Is Linked to Urinary Microbiome Changes.

    B. Modena, R. Milam, F. Harrison, S. Kurian, D. Salomon, A. Kirk.

    Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA.

    Purpose: The microbiome is important to human health and alteration may lead to aberrant immunity and disease. Interstitial fibrosis and tubular atrophy(IFTA) occurs in 20%…
  • 2016 American Transplant Congress

    The Relationship Between Kidney Donor Profile Index and Six Month eGFR in Deceased Donor Recipients.

    D. Keith, A. Nishio Lucar, G. Vranic.

    Division of Nephrology, University of Virginia, Charlottesville, VA.

    Kidney function, as measured by GFR, at 6 months post-kidney transplant is a powerful predictor of long-term post-transplant outcomes. This study sought to understand the…
  • 2016 American Transplant Congress

    Pre-Existing Chronic Heart Failure in Kidney Transplantation: An Underestimated Risk Factor for Graft Loss?

    F. Halleck, D. Khadzhynov, L. Lehner, E. Schrezenmeier, M. Duerr, A. Kleinsteuber, K. Budde, O. Staeck.

    Nephrology, Charité University, Berlin, Germany.

    BACKGROUND: Cardio-renal interactions influence graft and patient survival in kidney transplant recipients (KTR). There is only few data available analyzing pre-existing chronic heart failure (CHF)…
  • 2016 American Transplant Congress

    The mTORC2 Activation Is Critical for Hepato-Cytoprotection Against Ischemia and Reperfusion Injury.

    H. Zhou,1,2 J. Zhu,1,3 S. Yue,1 R. Busuttil,1 J. Kupiec-Weglinski,1 X. Wang,2 Y. Zhai.1

    1Surgery, David Geffen School of Medicine-University of California-Los Angeles, LA, CA; 2Liver Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China; 3Liver Surgery, Renji Hospital, Shanghai, China.

    Background & AimsRapamycin and Everolimus have been used in liver transplant patients, particularly those with calcineurin inhibitor-related nephrotoxicity and hepatocellular carcinoma. Although designed as mTORC1…
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