ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Comparison of Renal Outcomes Between ABO-Incompatible and Kidney Paired Donation Transplantation In Living Donors.

    N. Hashemi, M. Tavakol, B. Lee.

    Kidney Transplant Unit, UCSF, San Francisco, CA.

    Introduction: ABO incompatible transplantation (ABOi Tx) broadens the donor pool and decreases wait times for patients who don't have a blood type compatible living kidney…
  • 2016 American Transplant Congress

    Pre-Formed AT1R Antibodies Are Associated with Rejection After Kidney Transplantation.

    D. Kim, P. Warner, K. Nelson, I. Gimferrer, C. Johnson, C. Blosser, R. Bakthavatsalam, N. Leca.

    Nephrology, University of Washington, Seattle.

    Antibody mediated injury is a significant contributor to rejection and allograft damage. Non-HLA antibodies have been increasingly recognized in association with graft dysfunction. Our goal…
  • 2016 American Transplant Congress

    Exposure Analysis for the Composite Efficacy Endpoints in the US92 Phase 3 Kidney Transplantation Trial to Understand Center Effects.

    F. Shihab, B. Kaplan, K. McCague, D. Patel, F. Vincenti.

    University of Utah, Salt Lake City; Mayo Clinic, Phoenix; Novartis Pharmaceuticals Corporation, East Hanover; University of California, San Francisco.

    The US92 study determined whether, in de novo renal transplant patients, concentration-controlled everolimus (EVR) with reduced dose tacrolimus (RTAC) is non-inferior compared to CellCept®, (mycophenolate…
  • 2016 American Transplant Congress

    Analysis of T Cell Receptor Repertoire in Routine Renal Allograft Biopsy.

    R. Reindl-Schwaighofer,1 J. Weinberger,1 R. Jimenez-Heredia,1 J. Sunzenauer,1 S. Schaller,2 S. Winkler,2 R. Oberbauer.1

    1Department of Nephrology, Medical University of Vienna, Vienna, Austria; 2Bioinformatics Research Group, University of Applied Sciences Upper Austria, Hagenberg, Austria.

    Introduction: Diversity and clonality of the T cell repertoire of circulating and tissue-resident T-cells can be assessed by sequencing of recombined T cell receptor (TCR)…
  • 2016 American Transplant Congress

    Dysfunctional Production of Adipocytokines in Obesity Results in Inferior Oncologic Outcomes from Hepatocellular Carcinoma Following Liver Transplantation.

    A. Mathur, E. Presbyskowski, D. Carpenter, E. Zorn, J. Guarrera, B. Samstein, A. Griesemer, K. Halazun, Y. Veras, K. Tomoaki, J. Emond.

    Abdominal Transplant, Columbia University, Ny, NY.

    IntroductionOver 2 billion people worldwide are obese. There is strong evidence of an association between obesity and hepatocellular (HCC) cancer.This effect is mediated through an…
  • 2016 American Transplant Congress

    Barriers to the Wider Utilization of Living Donor Liver Transplantation (LDLT).

    A. Yegiants, E. Przybyszewski, A. Fox, J. Emond, B. Samstein.

    Center for Liver Disease and Transplantation, NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY.

    Purpose: LDLT reduces waitlist mortality, improves access to transplantation and has post-transplant outcomes that are equivalent to or better than deceased donor transplant. Despite these…
  • 2016 American Transplant Congress

    Functional Capacity Pre-Transplantation Measured by 6 Minute Walk Test and Clinical Outcomes.

    T. Alhamad,1 K. Lentine,2 S. Anwar,3 T. Maw,1 T. Horwedel,1 J. Peng,1 K. Saffaf,1 J. Hagopian,1 R. Delos Santos,1 A. Malone,1 D. Brennan.1

    1Washington University, St. Louis; 2Saint Louis University, St. Louis; 3Newcastle Hospital, Newcastle, United Kingdom.

    Background:The 6 minute walk is an inexpensive, low-technology test for measuring a patient's functional capacity and overall fitness. The utility of 6 minute walk test…
  • 2016 American Transplant Congress

    Acute Rejection: A Major Cause of Death-Censored Kidney Allograft Failure.

    M. Alkadi,1 J. Kim,1 C. Hartono,2 M. Aull,1 T. Muthukumar.1

    1Weill Medical College of Cornell University, New York; 2The Rogosin Institute, New York.

    Introduction:The role of acute rejection as a cause of kidney allograft failure is not well defined in the current era of immunosuppression. We analyzed the…
  • 2016 American Transplant Congress

    Impact of Pre-Existing Comorbidities on Long-Term Patient and Graft Survival in Kidney Transplant Recipients.

    F. Halleck, D. Khadzhynov, L. Lehner, E. Schrezenmeier, M. Duerr, A. Kleinsteuber, K. Budde, O. Staeck.

    Nephrology, Charité University, Berlin, Germany.

    BACKGROUND Outcomes of patients with end-stage renal disease are largely affected by their comorbidities. Detailed data evaluating the impact of pre-transplant comorbidities on the long-term…
  • 2016 American Transplant Congress

    Monocytic TNF-α Response to EBV Peptides as a Mean to Identify Over-Immunosuppressed Kidney Transplant Recipients.

    P. Vallin,1 O. Désy,1 S. Béland,1 E. Wagner,2 S. De Serres.1

    1Renal Division, Quebec University Health Center, Laval University, Quebec, QC, Canada; 2Immunology and Histocompatibility Laboratory, Quebec University Health Center, Laval University, Quebec, QC, Canada.

    Background. The reduction in acute rejection rates seen with the current triple immunosuppressive maintenance regimen has come at the expense of an increased risk of…
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