ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Significant Association of Vitamin-D Receptor (VDR) Gene Polymorphism and Incidence of De Novo DSA in Renal Transplantation.

    L. Das, K. Ide, Y. Tanaka, N. Tanimine, S. Verma, H. Ohdan.

    Department of Gastroenrological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.

    Objective-Renal Transplantation (RT) is the optimal choice forend stage renal disease. Despite all advances in the development ofeffective immunosuppressive regimens in renal transplantation one of…
  • 2016 American Transplant Congress

    The Live Donor Champion Program: A Novel Approach to Identying Live Kideny Donors.

    E. King, M. Bowring, K. Kumar, J. Garonzik Wang, D. Segev.

    Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD.

    Background: The Live Donor Champion (LDC) program is a clinical program offered to kidney waitlist candidates at our high volume transplant center. The six-month program…
  • 2016 American Transplant Congress

    Rapid Detection of Urinary CXCL9 as a Diagnostic and Prognostic Tool for Managing Acute Cellular Rejection (ACR) in Kidney Transplantation.

    I. Gandolfini,1 C. Harris,1 C. Purroy,1 V. Nair,1 J. Reid-Adam,1 O. Bestard,2 P. Heeger.1

    1Icahn School of Medicine at Mount Sinai, New York, NY; 2Bellvitge University Hospital, Barcelona, Spain.

    Urinary (u) CXCL9 protein expression can noninvasively diagnose ACR and serial measurements during CNI withdrawal indicate that elevations in uCXCL9 detect subclinical rejection. How elevated…
  • 2016 American Transplant Congress

    A Kidney Paired Donation Standard Acquisition Charge Pilot Program.

    M. Rees,1 L. Reece,2 S. Rees,2 B. Crandall,2 A. Leichtman.4

    1UT, Toledo; 2APKD, Perrysburg; 3Arbor Res, Ann Arbor.

    Background/Purpose: A national non-profit Kidney Paired Dontion (KPD) organization undertook a demonstration project to redesign payment for KPD transplants with a payment model similar to…
  • 2016 American Transplant Congress

    The Effect of Donor-Recipient Relationship on the Immunologic Outcome in Living Kidney Transplantation.

    D. Khadzhynov, F. Halleck, L. Lehner, M. Duerr, J. Waiser, K. Budde, O. Staeck.

    Nephrology, Charite Campus Mitte, Berlin, Germany.

    Background. Presensitization and degree of HLA-matching influences immunologic outcome and kidney graft survival. Thus the donor-recipient relationship may influence incidence of immunologic events and outcome…
  • 2016 American Transplant Congress

    Arterial Hypertension After Renal Transplantation in Pediatric Patients: An Analysis of CERTAIN Registry.

    R. Sugianto,1 E. Wühl,2 B. Schmidt,1 K. Krupka,2 B. Höcker,2 B. Tönshoff,2 A. Melk.1

    1Children's Hospital, Hannover Medical School, Hanover, Germany; 2Division of Pediatric Nephrology, University of Heidelberg, Heidelberg, Germany.

    BackgroundOur study aimed to describe the prevalence of hypertension & blood pressure (BP) control as well as influencing factors in pediatric renal transplant patients.MethodCasual BP…
  • 2016 American Transplant Congress

    Cross-Talk Between TLR and BCR Pathways Induces CNI-Resistance in B-Cells Responding to Blood Group A-Antigens: A Novel Paradigm for Treatment with TLR-Inhibitor for CNI-Resistant AMR.

    H. Sakai, Y. Tanaka, H. Ohdan.

    Hiroshima University, Hiroshima, Japan.

    [Aim] Bacterial infections after ABO-incompatible transplantation are associated with refractory antibody (Ab)-mediated rejection (AMR). We demonstrated that bacterial pathogens provoke B cells, responding to human…
  • 2016 American Transplant Congress

    IL2 and IL-15 Rescue TEMRA CD8 T Cells from Mitochondrial Dysfunction Associated Senescence Through a p38MAPK Dependent Pathway and Foster Their Pathogenic Potential.

    G. Tilly,1,2 M. Yap,1,2 M. Giral,1,2,3 C. Pecqueur,4 S. Brouard,1,3 N. Degauque.1,3

    1UMR1064, INSERM, Nantes, France; 2Université de Nantes, Nantes, France; 3ITUN, CHU de Nantes, Nantes, France; 4UMR892, INSERM, Nantes, France.

    Background & Study Aim. We recently showed that an accumulation of highly differentiated TEMRA CD8 T cells in kidney transplant recipients with a stable graft…
  • 2016 American Transplant Congress

    In Vitro Induction of T Regulatory Cells by Multipotent Adult Progenitor Cells.

    S. Stubblefield, N. Williams, A. Ting.

    Regenerative Medicine, Athersys, Inc, Cleveland, OH.

    There is increasing evidence that transplanted adult stemcells remain undifferentiated and often are cleared after a short time.However, these short-lived stem cells still promote recovery…
  • 2016 American Transplant Congress

    Use of Integrated National Registry and Pharmacy Claims Data to Identify Diabetes Mellitus After Live Pancreas Donation.

    K. Lentine,1,7 N. Lam,2 H. Randall,8 D. Axelrod,3 D. Segev,4,1 G. Hess,5 A. Garg,6 D. Brennan,7 B. Kasiske,8 M. Schnitzler.8,1

    1Scientific Registry of Transplant Recipients, Minneapolis; 2Univ Alberta, Alberta, Canada; 3Dartmouth, Hanover; 4Johns Hopkins, Baltimore; 5Symphony Health, Pittsburgh; 6Western Univ, London, Canada; 7Washington Univ, St. Louis; 8Saint Louis Univ, St. Louis.

    Living donor pancreas transplant is a potential treatment for diabetic patients with end-organ complications. Early post-donation surgical risks of living pancreas donation have been reported,…
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