2016 American Transplant Congress
Predicting Obstructive Coronary Artery Disease in Asymptomatic Patients Undergoing Renal Transplantation Using a Simple Risk Score.
Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
PurposeCoronary angiography in asymptomatic patients with End Stage Renal Disease (ESRD) shows significant Coronary Artery Disease (CAD) (stenosis >50%) in 37-53% of patients. We have…2016 American Transplant Congress
Tolerance Induction with Donor Bone Marrow Transplantation in Kidney Transplantation.
Tolerance induction is considered to be a final goal in the field of organ transplantation. We have performed simultaneous bone marrow and kidney transplantation in…2016 American Transplant Congress
Factors Associated with Mortality Among a Large Population of Patients with Cirrhosis and a Low MELD (<15).
Northwestern University, Chicago.
AimStudies suggest that certain patients with liver cirrhosis and a low MELD score (<15) remain at high risk for mortality. Current data is largely limited…2016 American Transplant Congress
Erythropoietin (EPO) Mediates Spontaneous Kidney Transplant Tolerance in Mice.
Spontaneous allogeneic kidney transplant tolerance occurs in mice, but the underlying mechanisms are unknown. Building upon recent human data showing that EPO, an erythropoietic hormone…2016 American Transplant Congress
Ageing as a Barrier to Transplant Tolerance.
Surgery/Transplant, Massachusetts General Hospital, Harvard Medical, Boston, MA.
We recently demonstrated that ageing also impedes development of transplantation tolerance. Unlike their young counterparts (8-12 weeks of age) aged male recipients (greater than 12…2016 American Transplant Congress
The Largest Single Center Experience with Total Artificial Heart Implantation: Characterization of Outcome.
Cedars-Sinai Heart Institute, Los Angeles, CA.
Background: Patients with severe irreversible biventricular heart failure may require support with the total artificial heart (TAH). These patients are usually Intermacs level 1 or…2016 American Transplant Congress
Is Facilitated Pancreas Allocation Effective?
Background: OPTN policy exists that allows the UNOS Organ Center to facilitate the allocation of a pancreas within 1 hr. of donor surgery, permissible only…2016 American Transplant Congress
Selective Deletion of Notch2 on B Cells Abrogates Alloantibody Production in Fully MHC-Mismatched Cardiac and Skin Transplant Models.
Alloantibody-mediated injury remains a major challenge for the improvement of long-term graft survival and there is no effective therapy to prevent alloantibody generation post-transplant. The…2016 American Transplant Congress
The 20S Proteasome, Active within Exosome-Like Vesicles Released by Apoptotic Cells Accelerates Rejection.
Apoptotic bodies (ApoBodies) and apoptotic exosome-like MV (ApoExo) released by apoptotic endothelial cells in vitro were purified by sequential centrifugation and analysed by electron microscopy…2016 American Transplant Congress
Pre-Transplant Infusion of Extracorporeal Photopheresis Treated Donor Splenocytes Leads to Long-Term Liver Allograft Survival and Donor Specific Tolerance in Rats.
Extracorporeal photopheresis (ECP), a procedure that exposes isolated WBC to photoactivatable 8-methoxypsoralen and ultraviolet A radiation, is used clinically to treat patients with cutaneous T-cell…
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