Am J Transplant, Volume 16, Suppl 3 Archives - Page 103 of 180 - ATC Abstracts

2016 American Transplant Congress
IFN-γ and Contact-Dependent Cytotoxicity Are Rate-Limiting for NK Cells in a Model of Antibody-Mediated Chronic Rejection.
C. Lin,¹ R. Plenter,¹ R. Gill.²
¹Medicine, University of Colorado, Denver, Aurora, CO; ²Surgery, University of Colorado, Denver, Aurora, CO.
BACKGROUND. Natural killer (NK) cells are key components of the innate immune that contribute to acute and chronic graft rejection. After engagement with antibody, NK…
2016 American Transplant Congress
ASC-Deficient Dendritic Cells Exhibit Activation Defects and a Reduced Ability to Stimulate Allogeneic T Cells.
A. Scheinok, A. Shigeoka, S. Kasimsetty, R. Elahimehr, D. McKay.
Medicine, University of California-San Diego, La Jolla, CA.
Donor dendritic cell (DC) activation causes adaptive immune responses that lead to rejection of transplanted allografts. Accumulating data suggest that inflammasome assembly within interstitial DCs…
2016 American Transplant Congress
Bortezomib Impacts Tenascin mRNA in PBMNCs.
E. Bradley, O. Moussa, K. Twombley.
Medical University of South Carolina, Charleston.
Tenascin (TNC) is a gene thought to play a role in the binding of receptors and syndecan binding. Syndecans are signal transmembrane proteins that act…
2016 American Transplant Congress
Impact of Simultaneous Pancreas-Kidney Transplantation versus Kidney Transplant Alone on Patient and Graft Survival in Type 2 Diabetics with Elevated BMI.
S. Singh,^1,2 S. Kim.^1,2,3,4
¹Division of Nephrology, Department of Medicine, University of Toronto, Toronto, Canada; ²Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada; ³Division of Nephrology and the Multi-Organ Transplant Program, University Health Network, Toronto General Hospital, Toronto, Canada; ⁴Division of Nephrology and the Kidney Transplant Program, St. Michael's Hospital, Toronto, Canada.
Background: Simultaneous Pancreas-Kidney transplantation (SPKT) is becoming increasingly common in patients with Type 2 diabetes (T2DM). The BMI threshold for listing for SPKT in this…
2016 American Transplant Congress
Injurious Procoagulant Pathways During Prolonged Cold Storage of the Donor Pancreas.
B. Sandhu, S. Charitidou, N. Vallant, A. McLean, D. Taube, P. DiCocco, P. Herbert, J. Crane, V. Papalois.
West London Renal and Transplant Centre, London, United Kingdom.
Background: Analyses of pancreas transplant outcomes have revealed that pancreatic grafts exhibit an enhanced intolerance to prolonged cold ischaemia time (CIT), however the underlying pathophysiology…
2016 American Transplant Congress
Vascular Composite Allotransplantation Collaborative Initiative Biobank: Bringing the Power Back to Research.
J. Cheeseman, M.-B. Joshi, F. Leopardi, R. Osborne, D. Conlon, L. Stempora, M. Song, L. Cendales.
Surgery, Duke University, Durham, NC.
Refining Vascular Composite Allotransplantation (VCA) into a useful therapeutic option for patients in need of tissue reconstruction depends on the availability of biological specimens and…
2016 American Transplant Congress
Highly Sensitized Patients Transplanted via the Eurotransplant Acceptable Mismatch Program Have Excellent Long-Term Graft Survival.
S. Heidt, M. Witvliet, G. Haasnoot, F. Claas.
Eurotransplant Reference Laboratory, Leiden University Medical Center, Leiden, Netherlands.
The Eurotransplant Acceptable Mismatch (AM) program has been initiated 25 years ago in order to enhance transplantation of highly sensitized renal transplant candidates. Instead of…
2016 American Transplant Congress
Donor-Candidate Mismatch in Age, Sex, HLA, and Body Size Inform a Calculator for Kidney Graft Survival.
J. Kalbfleisch,¹ V. Ashby,¹ A. Leichtman,² M. Rees,³ P. X.-L. Song,¹ A. Sakhuja,¹ M. Bray,¹ R. Eikstadt,¹ A. Goulding,¹ W. Wang.¹
¹Univ of Michigan, Ann Arbor; ²Arbor Research, Ann Arbor, MI; ³Univ of Toledo, Toledo, OH.
Using Scientific Registry of Transplant Recipients data, we analyzed 232,705 kidney transplant recipients that received a transplant from 1998-2012. Graft failure rates were estimated using…
2016 American Transplant Congress
Outcomes of Donor Nephrectomy (DN) in the Obese.
O. Serrano,¹ A. Bangdiwala,² D. Vock,³ E. Minja,¹ W. Payne,¹ T. Dunn,¹ S. Chinnakotla,¹ E. Finger,¹ T. Pruett,¹ A. Matas,¹ R. Kandaswamy.¹
¹Surgery, Univ. of Minnesota, Minneapolis, MN; ²Biostatistics and Bioinformatics Core, Masonic Cancer Center, Minneapolis, MN; ³Biostatistics, Univ. of Minnesota, Minneapolis, MN.
PURPOSE: In an effort to address the critical organ shortage and rising obesity rates, the criteria for live kidney donation (LKD) have been expanded to…
2016 American Transplant Congress
Clinical Impact of Pre-Transplant Serum 25-Hydroxyvitamin D Levels on the Post-Transplant Immunologic and Non-Immunologic Outcomes in Kidney Transplant Recipients.
T. Ban,^1,2 J. Kim,^1,2 Y. Lee,¹ B. Choi,^1,2 C. Park,^1,2 C. Yang,^1,2 Y.-S. Kim,^1,2 B. Chung.^1,2
¹Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, Seoul, Korea; ²Transplant Research Center, Seoul St. Mary's Hospital, Seoul, Korea.
Background: The aim of this study is to investigate the clinical significance of pre-transplant serum 25-hydroxyvitamin D (25(OH)D) levels in regard to post-transplant clinical outcome…