Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall 4EF
One option for using organs from donors with a suboptimal nephron mass, e.g. expanded criteria donors (ECD) kidneys, is dual kidney transplantation (DKT)
Methods: Ninety-three DKT were performed, among January 2006 until November 2017, using kidneys from ECD donors. The results of unilateral DKT (UDKT, group 1 n=34) in same iliac fossa were compared with a cohort of DKT performed with bilateral placement of each kidney (BDKT) with the same donor and recipient selection criteria in the same study period (Group 2, n = 59). No difference among groups in term of donor sex, age, BMI, Karpinsky score, cause of donor death; no difference also in term of recipient sex, median age, BMI, start of dyalisis, presence of diabetes, vascular calcification and cardiac diseases.
Results: All vascular anastomoses were to the external iliac vessels end-to-side in the UDKT group. Mean operating time was shorter in UDKT group (319 minutes vs 733, p< 0.0001), second kidney graft ischemia time was shorter in UDKT group (740 minutes vs 997). Surgical complications were comparable in both groups in term of ureteral stenosis (4.3% vs 3.3%, p=0.05), venous thrombosis (0% vs 1.9%, p=0.05), arterial thrombosis (0% vs 1.9%, P=0.05) but in the UDKT group the incidence of ureteral fistula was higher (8.6% vs 5.08%, p=0.04). At 3-year follow-up, patient and graft survival rates were 100% and 100%% in Group 1, and 98% and 93% in Group 2, respectively. The incidence of delay graft function was 13% vs 25% (p=0.04) in the Group 1 and 2, respectively.
Conclusion: UDKT can be carried out with comparable surgical complication rates as BDKT, leaving the contralateral iliac fossa untouched and giving elderly recipients a better chance of receiving a transplant, with optimal results up to 3-years follow-up.
CITATION INFORMATION: Del Gaudio M., Ravaioli M., Zanfi C., Bertuzzo V., Maroni L., La Manna G., Liviano G., Siniscalchi A., D'Errico A., Pinna A. Unilateral vs. Bilateral Dual Kidney Transplantation: University of Bologna Experience Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:Gaudio MDel, Ravaioli M, Zanfi C, Bertuzzo V, Maroni L, Manna GLa, Liviano G, Siniscalchi A, D'Errico A, Pinna A. Unilateral vs. Bilateral Dual Kidney Transplantation: University of Bologna Experience [abstract]. https://atcmeetingabstracts.com/abstract/unilateral-vs-bilateral-dual-kidney-transplantation-university-of-bologna-experience/. Accessed February 24, 2020.
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