Date: Tuesday, June 5, 2018
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall 4EF
Background:Graft reperfusion holds a major challenge during liver transplantation. NMP may improve post-reperfusion hemodynamics, reduce vasopressor and blood product transfusion.
Methods:15 patients with liver transplantation after NMP were matched with Cold storage (CS) group.Intraoperative records of vasopressors, arterial blood gas, TEG parameters, and blood products during post-reperfusion phase were collected. Post-reperfusion syndrome was defined as severe hemodynamic instability (mean arterial pressure dropped >30% of the anhepatic level),asystole, arrhythmias or fibrinolysis.
Results: NMP group had lower post-reperfusion syndrome rate (13 % (2) vs. 46 % (28), p=0.01), and received less amount of PRBC, FFP, cryoprecipitate and crystalloids compared to CS group.TEG coagulation index was higher in NMP than CS.
|NMP N=15||CS N=60||p|
|MAP drop>30%||0||5% (3)||0.3|
|Degree Angle||42 ±14||42±12||0.9|
Conclusion:NMP is associated with more stable hemodynamic, reduced post-reperfusion syndrome rate, better metabolic and coagulation profile after reperfusion compared to CS group, which needs to be investigated in larger study.
CITATION INFORMATION: Hassan A., Cywinski J., Liu Q., Pezzati D., Yang D., Liu L., Iuppa G., Hashimoto K., Aucejo F., Fujiki M., Eghtesad B., Irefin S., Fung J., Abu-Elmagd K., Miller C., Quintini C. The Role of Ex Vivo Normothermic Preservation in Minimizing Postreperfusion Syndrome in Liver Transplantation Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:Hassan A, Cywinski J, Liu Q, Pezzati D, Yang D, Liu L, Iuppa G, Hashimoto K, Aucejo F, Fujiki M, Eghtesad B, Irefin S, Fung J, Abu-Elmagd K, Miller C, Quintini C. The Role of Ex Vivo Normothermic Preservation in Minimizing Postreperfusion Syndrome in Liver Transplantation [abstract]. https://atcmeetingabstracts.com/abstract/the-role-of-ex-vivo-normothermic-preservation-in-minimizing-postreperfusion-syndrome-in-liver-transplantation/. Accessed March 1, 2021.
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