ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Subnormothermic Machine Perfusion (SNMP) with a Novel Hemoglobin-Based Oxygen Carrier (HBOC) Solution for Ex Vivo Preservation in Vascularized Composite Allotransplantation (VCA).

    S. Oksuz, R. Schweizer, M. Minervini, B. Banan, V. Gorantla, P. Fontes.

    University of Pittsburgh, Pittsburgh.

    Background: Improved preservation techniques could reduce ischemia-reperfusion injuries (IRI) and allow better matching and allocation of VCA grafts across wider distances. A novel SNMP system…
  • 2016 American Transplant Congress

    Developing a PCR-Based System to Access the Correlation of Local Chimerism and Fate of the Vascularized Composite Allotransplant.

    X.-T. Huang,1 H.-Y. Cheng,1 C.-F. Lin,1 S.-S. Qiu,2 L.-Y. Shih,1 F.-C. Wei.1,2,3

    1Center for Vascularized Composite Allotransplantation, Chang Gung Memorial Hospital, Gueishan, Taoyuan, Taiwan; 2Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Gueishan, Taoyuan, Taiwan; 3College of Medicine, Chang Gung University, Gueishan, Taoyuan, Taiwan.

    It is established that development of mixed chimerism following allotransplantation is associated with induction of tolerance to allotransplants. Although chimerism in peripheral blood can be…
  • 2016 American Transplant Congress

    Membrane Proteome Profiling Reveals Molecular Changes Associated with Donor-Specific Tolerance to Vascularized Composite Allotransplants.

    H.-Y. Cheng,1 C.-L. Han,2 F.-W. Jiang,2 L.-Y. Shih,1 C.-F. Lin,1 Y.-J. Chen,3 F.-C. Wei.1,4

    1Center for Vascularized Composite Allotransplantation, Chang Gung Memorial Hospital, Gueishan, Taoyuan, Taiwan; 2Master Program for Pharmacogenomics and Pharmacoproteomics, Taipei Medical University, Taipei, Taiwan; 3Institute of Chemistry, Academia Sinica, Taipei, Taiwan; 4College of Medicine, Chang Gung University, Gueishan, Taoyuan, Taiwan.

    Background: although donor-specific tolerance to vascularized composite allotransplants (VCAs) has been successfully induced with different regimes, molecular changes associated with tolerance are not well understood.Materials…
  • 2016 American Transplant Congress

    Hospital Readmissions Following Incompatible Kidney Transplantation: A Multi-Center Study.

    B. Orandi, E. King, X. Luo, S. Bae, B. Lonze, R. Montgomery, D. Segev.

    Johns Hopkins, Baltimore.

    Desensitization and incompatible live donor kidney transplantation (ILDKT) has improved survival vs. forgoing transplant or waiting for a compatible one. It is unknown if increased…
  • 2016 American Transplant Congress

    Enabled PRA and Precision PRA: Alternatives to cPRA as Desensitization Trial Endpoints.

    E. Woodle, M. Pando Rigal, S. Tremblay, A. Girnita.

    U of Cincinnati, Cincinnati; Mayo Clinic Scottsdale, Scottsdale.

    Transplant (Transplant) rate is an optimal endpoint in desensitization (DS) trials in HLA sensitized Txp candidates, however, for waitlisted Txp candidates, wait time heterogeneity compromises…
  • 2016 American Transplant Congress

    Early Hospital Readmission Among Immunologically Vulnerable Kidney Transplantation Recipients.

    E. King, B. Orandi, S. Bae, X. Luo, D. Segev.

    Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD.

    BACKGROUND: We previously established that 31% of all kidney transplant (KT) recipients experience early hospital readmission (EHR), or readmission within 30 days of discharge following…
  • 2016 American Transplant Congress

    Everolimus Decline Anti-ABO Blood Type Antibody Titer in Desensitization for ABO Incompatible Kidney Transplantation.

    Y. Wada, N. Fukuzawa, H. Harada.

    Kidney Transplantation Surgery, Sapporo City General Hospital, Sapporo, Hokkaido, Japan.

    INTRODUCTION: The immoderate donor shortage and sophisticated desensitization protocols resulted in the explosive increase and great success of the ABO blood type incompatible kidney transplantation…
  • 2016 American Transplant Congress

    Highly Sensitized Patients Transplanted via the Eurotransplant Acceptable Mismatch Program Have Excellent Long-Term Graft Survival.

    S. Heidt, M. Witvliet, G. Haasnoot, F. Claas.

    Eurotransplant Reference Laboratory, Leiden University Medical Center, Leiden, Netherlands.

    The Eurotransplant Acceptable Mismatch (AM) program has been initiated 25 years ago in order to enhance transplantation of highly sensitized renal transplant candidates. Instead of…
  • 2016 American Transplant Congress

    The Effect of Rituximab on Hepatitis B Reactivation in Kidney Transplant Recipients with Resolved Hepatitis B.

    J. Lee,1 J. Park,2 J. Lee,1 S. Song,1 J. Lee,1 S.-K. Kwon,1 K. Huh,1 B. Kim,3 M. Kim,1 S. Kim,1 S. Ahn,2 Y. Kim.1

    1Surgery, Yonsei University College of Medicine, Seoul, Korea; 2Internal Medicine (Gastroenterology), Yonsei University College of Medicine, Seoul, Korea; 3Internal Medicine (Nephrology), Yonsei University College of Medicine, Seoul, Korea.

    Background: Hepatitis B virus (HBV) reactivation is a well-known complication of immunosuppressive therapy in resolved HBV (hepatitis B surface antigen [HBsAg] negative and hepatitis B…
  • 2016 American Transplant Congress

    Incidence of Viral Infections in HLA-Sensitized Patients (HS Pts) Desensitized with IVIG + Rituximab (DES) Compared to Non-HS Pts Receiving Standard Immunosuppression.

    S. Jordan, J. Choi, B. Shin, J. Kahwaji, S. Ge, D. Thomas, A. Vo, O. Galera, R. Villicana, A. Peng, M. Toyoda.

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.

    Introduction: HS pts (PRA>50%, DSA+ at transplant) who are transplanted without DES represent a significant risk for antibody-mediated rejection. Prior to transplantation, HS pts require…
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