ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Influence of AKIN Stage on the Outcome of Deceased Donor Kidney Transplantation (DDKTx).

I. Qaqish, D. Haakinson, K. Reddy, M. Smith, H. Khamash, H. Raymond.

Mayo Clinic, Phoenix, AZ.

Meeting: 2016 American Transplant Congress

Abstract number: 274

Keywords: Graft function, Graft survival, Kidney transplantation, Renal injury

Session Information

Date: Monday, June 13, 2016

Session Name: Concurrent Session: Acute Kidney Injury and Recovery after Transplantation

Session Time: 4:30pm-6:00pm

 Presentation Time: 5:30pm-5:42pm

Location: Ballroom C

Related Abstracts
  • Impact of Donor AKI on Outcome Following High KDPI Deceased Donor Kidney Transplantation.
  • Donor AKI Does Not Adversely Affect the Outcome Following DCD Kidney Transplant.

Background

Transplanting kidneys from donors with AKI is one of the methods to minimize the disparity between numbers of listed patient and donor pool. Our aim is to determine the influence of AKIN classification of donors on outcomes following DDKTx.

Methods

We included all DDKTx transplanted at our center between January 2008 and February 2015. Using data from DonorNet, we classified all donors using the AKIN Staging (0-3). The primary outcome was graft survival at 1, 3 and 5 years post-transplant. The secondary outcome was delayed graft function (DGF), defined as requirement of dialysis or failure of creatinine drop more than 30% within 3 days of transplant. Survival analysis between groups were done using the Kaplan-Meier method. Continuous data shown as mean ±SD.

Results

The AKIN stage could be determined for 804 of 815 who received DDKTx during the study period. The risk of DGF progressively increased with increasing AKIN stage. Graft survival at 1, 3 and 5 years stratified by the AKIN stage was not different between the groups (p=0.19).

  1 year 3 year 5 year
AKIN 0 (n=169) 93.5% 84.3% 77.8%
AKIN 1 (n=298) 94.6% 86.4% 78.0%
AKIN 2 (n=138) 95.5% 87.7% 82.1%
AKIN 3 (n=199) 96.5% 93.6% 81.3%

The mean donor age (±SD) for the four groups were 37.2±21 ,44.8±17.6, 41.2±16.1 and 35±14.6 years respectively (p<0.0001) and KDPI (±SD) were 42±28, 56±28, 52±27 and 49±24 respectively (p=0.017). There were no differences in rejection rate during the first year, BK infection, serum creatinine or eGFR(CKD EPI) at 1 year between the groups.

Conclusion

Our results shows that donor AKIN staging is strongly correlated with the risk of DGF, however increasing donor AKIN stage does not adversely effect graft survival.

CITATION INFORMATION: Qaqish I, Haakinson D, Reddy K, Smith M, Khamash H, Raymond H. Influence of AKIN Stage on the Outcome of Deceased Donor Kidney Transplantation (DDKTx). Am J Transplant. 2016;16 (suppl 3).

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Qaqish I, Haakinson D, Reddy K, Smith M, Khamash H, Raymond H. Influence of AKIN Stage on the Outcome of Deceased Donor Kidney Transplantation (DDKTx). [abstract]. Am J Transplant. 2016; 16 (suppl 3). https://atcmeetingabstracts.com/abstract/influence-of-akin-stage-on-the-outcome-of-deceased-donor-kidney-transplantation-ddktx/. Accessed February 28, 2021.

« Back to 2016 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • A Decade of Donor-Derived Disease: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Penis Transplantation: First U.S. Experience.
  • A Decade of Donor-Derived Disease: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Evidence of a Clinically Significant Drug-Drug Interaction between Cannabidiol and Tacrolimus: A Case Report
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.