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2022 American Transplant Congress

TOPIC: Basic Science » Basic Science » 12 - Immunosuppression & Tolerance: Preclinical & Translational Studies

  • A Novel Immunosuppressive Compound (79-6) That Targets Bcl6 Prevents the Humoral Alloresponse

    R. Kraaijeveld, D. A. Hesselink, C. C. Baan

  • Achievement of Persistent Mixed Chimerism in Recipients of Matched and Mismatched Living Donor Kidney Transplants in a Tolerance Induction Protocol

    J. D. Scandling, S. Busque, R. Lowsky, T. Pham, R. Hoppe, K. Jensen, A. Shori, H. Wu, R. Pawar, E. Engleman, E. Meyer, S. Strober

  • Adenosine A2A Receptor (A2AR) Agonist Apadenoson Promotes Survival in K28-hACE2 Mice and Syrian Hamsters Infected with Sars-CoV-2

    P. Chhabra1, B. Mann2, M. Ma1, S. Feldman3, J. Linden4, K. L. Brayman1

  • Alloreactive Regulatory T Cells Release Distinct Subpopulations of Extracellular Vesicles Bearing Immune Regulatory Proteins and the TCR/CD3 Complex Under Antigen Specific Stimulation

    B. Schreiber, S. Tripathi, A. Sonawane, M. Blaser, S. Kuraoka, S. Singh, M. Aikawa, E. Aikawa, A. Chandraker

  • Apheresis of Deceased Donors: A New Source of Mobilized Peripheral Blood Hematopoietic Stem Cells for Transplant Tolerance

    R. A. Sosa1, T. Mone2, B. V. Naini1, D. B. Kohn3, E. F. Reed1, K. Wheeler2, B. Campo-Fernandez3, A. Davila3, D. J. Chaffin4, J. DiNorcia5, F. M. Kaldas5, A. Cohen2, E. Lum6, J. L. Veale7, N. M. Kogut7

  • Belatacept Augments Mixed Chimerism in a Novel Nonhuman Primate Kidney Transplant Tolerance Induction Protocol

    S. C. Kim, C. J. Little, J. H. Fechner, P. J. Chlebeck, J. Post, A. D'Alessandro, D. B. Kaufman

  • Belatacept-Based Maintenance Immunosuppression Promoted Long-Term Antibody-Mediated Rejection Free Graft Survival After Desensitization in Sensitized Multiparous Female Recipients

    M. Manook, I. Anwar, R. Schmitz, Z. Fitch, J. Yoon, A. Jackson, J. Kwun, S. Knechtle

  • CD209+ Macrophages-Mediated Immunosuppressive Effects in ADPKD Tissues

    Z. Ou1, Y. Wang1, Z. Yan1, Y. Liu1, Q. Li1, Y. Fang1, J. Geng1, W. Deng1, Z. Li1, R. Xia1, W. Zeng1, J. Xu1, C. Wu2, Y. Miao1

  • Differences of Fk-Binding Protein 12 and P-Glycoprotein Explain the Differences in the Intracellular Tacrolimus Concentration of T Lymphocytes and Monocytes

    S. Udomkarnjananun, C. Baan, B. de Winter, D. Hesselink

  • Differing Gene Expression Profiles and Signaling Pathways Observed Between Alloreactive and Tolerant T Cells in a Recipient Following Bilateral Orthotopic Lung Transplant (BOLT) and Bone Marrow Transplant (BMT) from the Same Cadaveric UNOS Donor

    P. Szabolcs, E. Garchar, D. Rajasundaram, X. Chen

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