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Articles tagged "Urinalysis"

  • 2019 American Transplant Congress

    Multidisciplinary Transplant UTI Service; Challenging the Stalemate

    J. J. Chong, A. Adiki, D. Ness, J. Olsburgh, R. H. Zakri

    Guy's Hospital, London, United Kingdom

    *Purpose: Symptomatic UTIs (urinary tract infections) cause a significantly detrimental effect on long term graft function. Immunosuppression coupled with underlying renal or urological abnormality makes…
  • 2019 American Transplant Congress

    Characterization Of Microscopic Hematuria Following Renal Transplant

    M. L. McDonald1, T. N. Duong2, N. Datta2, H. A. Gritsch1, S. Bunnapradist2

    1Department of Urology, Kidney and Pancreas Transplant Programs, UCLA, Los Angeles, CA, 2Division of Nephrology, Kidney and Pancreas Programs, UCLA, Los Angeles, CA

    *Purpose: The American Urological Association (AUA) recommends a CT Urography and cystoscopy for the evaluation of a single episode of microscopic hematuria (MH) in the…
  • 2019 American Transplant Congress

    Transport Medium Fluid Cultures in Paediatric Renal Transplantation: Are We Ready to Make a Consensus on Prophylaxis?

    D. Furnell1, S. Boyle1, N. Kessaris2, S. D. Marks1, J. Stojanovic1

    1Nephrology, Great Ormond Street Hospital, London, United Kingdom, 2Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom

    *Purpose: To establish the rate of positive transport medium fluid cultures and sensitivity to antibiotics in paediatric renal transplant recipients.*Methods: We analysed the electronic records…
  • 2018 American Transplant Congress

    Activity Nanosensors for Early and Noninvasive Detection of Acute Organ Transplant Rejection

    Q. Mac,1 D. Mathews,2 J. Kahla,1 C. Stoffers,1 O. Delmas,1 B. Holt,1 A. Adams,2 G. Kwong.1

    1Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA; 2Department of Surgery, Emory University School of Medicine, Atlanta, GA.

    Purpose: We engineered activity nanosensors that sense anti-allograft T cell activity in vivo to noninvasively detect the onset of acute cellular rejection from urine.Methods: Granzyme…
  • 2018 American Transplant Congress

    Non-Invasive Diagnostic of Renal Allograft Rejection via Urine Metabolites Using NMR-Spectroscopy

    M. Banas,1 S. Neumann,2 P. Pagel,2 D. Chittka,1 V. Pfahlert,2 B. Banas.1

    1Department of Nephrology, University Hospital Regensburg, Regensburg, Germany; 2numares HEALTH, Regensburg, Germany.

    Introduction and BackgroundPost-transplant surveillance for acute rejection is typically based on regular monitoring of serum creatinine levels and consecutive biopsies upon functional renal impairment. Attempts…
  • 2018 American Transplant Congress

    Diagnostic Value and Confounding Factors of Urinary Biomarkers in the Non-Invasive Screening of Renal Allograft Inflammation

    A. Vermorel,1 A. Devresse,1 C. Tinel,1,2 V. Sauvaget,2 L. Morin,2 L. Amrouche,1,2 M. Rabant,2,3 D. Anglicheau.1,2

    1Renal Transplantation Unit, Necker-Enfants Malades Hospital, Paris, France; 2INSERM U1173, Institut Necker Enfants Malades, Paris, France; 3Pathology, Necker-Enfants Malades Hospital, Paris, France.

    IntroductionThe value of urinary biomarkers has already been demonstrated in diagnosing acute rejection of the renal allograft, but confounding factors, which may interfere with their…
  • 2018 American Transplant Congress

    Urinary TIMP-2 Predicts the Presence and Duration of Delayed Graft Function in DCD Kidney Transplant Recipients

    J. Bank,1 R. Ruhaak,2 D. Soonawala,1 F. Romijn,2 C. van Kooten,1 C. Cobbaert,2 H. de Fijter.1

    1Nephrology, Leiden University Medical Center, Leiden, Netherlands; 2Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, Netherlands.

    Introduction: Tissue inhibitor of metalloproteinases-2 (TIMP-2) and insulin-like growth factor-binding protein 7 (IGFBP7) are promising biomarkers in acute kidney injury. Here, we investigated the performance…
  • 2018 American Transplant Congress

    Urinary Microbiome Associated with Chronic Allograft Dysfunction in Kidney Transplants

    A. Israni,1,2 A. Muthusamy,2 B. Wu,3 B. Guo,3 D. Knights,4 G. Al-Ghalith,4 J. Wu,1 W. Oetting,5 D. Schladt,2 R. Remmel,5 P. Jacobson,5 For DeKAF Genomics & GEN03 Investigators.1

    1Medicine, Hennepin County Medical Center, University of Minnesota (UMN), Minneapolis; 2Minneapolis Medical Research Foundation, Mpls; 3Biostatistics, UMN, Mpls; 4Computer Science, UMN, Mpls; 5College of Pharmacy, UMN, Mpls.

    Background: Microbiome dysbiosis can lead to poor outcomes after kidney transplant (tx) presumably due to immune dysregulation elicited by the microbiome. We hypothesize that chronic…
  • 2018 American Transplant Congress

    Urinary Tract Infections May Be Associated with De Novo Donor-Specific Anti-Human Leucocyte Antigen Antibodies: Single-Center Study

    M. Everly,1 A. Babu,1 K. Briley,2 P. Bolin,2 S. Kendrick,3 H. Jones,3 K. McLawhorn,3 A. Maldonado,4 C. Haisch,2 D. Leeser,2 L. Rebellato.2

    1Terasaki Research Institute, Los Angeles; 2East Carolina University, Greenville, NC; 3Eastern Nephrology Associates, Greenville, NC; 4Vidant Medical Center, Greenville, NC.

    Introduction: We have recently shown that immunosuppression reduction with BK virus is associated with the development of de novo donor anti-human leukocyte antigen-specific antibodies (dnDSA).…
  • 2017 American Transplant Congress

    Kinetic Estimation of Glomerular Filtration Rate and Urine Creatinine as Predictors of Delayed Graft Function in Kidney Transplantation from Non-Heart Beating Donors.

    M. Calvo, M. Moreno De La Higuera, V. Lopez De La Manzanara, A. Shabaka, M. Poma, I. Perez-Flores, N. Calvo Romero, B. Rodríguez-Cubillo, A. Sanchez-Fructuoso.

    Nephrology, Hospital Clínico San Carlos, Madrid, Spain

    Predicting the occurrence of delayed graft function (DGF) and its duration can facilitate the management of patients after kidney transplantation (KT). Methods: A retrospective study…
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