ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Articles tagged "T cell receptors (TcR)"

  • 2021 American Transplant Congress

    Precision Medicine in Renal Transplantation: T-cell Repertoire Sequencing to Define Donor-specific Clones for Post-transplant Monitoring

    K. R. Sherwood1, P. Wong1, F. Fenninger1, V. Wu1, J. Beckrud2, D. P. Cina3, L. Allan2, J. Lan2, P. A. Keown2

    1University of British Columbia, Vancouver, BC, Canada, 2Vancouver General Hospital, Vancouver, BC, Canada, 3Urologic Sciences, Vancouver General Hospital, Vancouver, BC, Canada

    *Purpose: Measuring donor-specific clonal responses offers a precise, sensitive and specific biomarker of immune recognition and activation. Combining deep immunophenotyping (DI) and T-cell receptor (TCR)…
  • 2020 American Transplant Congress

    T-cell Receptor Deep Sequencing to Distinguish Autoimmune Recurrence from Allograft Rejection in Liver Transplant Patients with Autoimmune Liver Disease

    K. J. Yang1, M. Martinez2, B. Shonts1, C. A. Parks1, A. Z. Obradovic1, T. M. Savage1, E. Spyrou1, S. Lau1, M. I. Colquhoun1, K. Rodgers1, E. Verna3, S. M. Coley4, S. Yang1, Y. Shen5, M. Sykes1

    1Columbia Center for Translational Immunology, Department of Medicine, Columbia University, New York, NY, 2Department of Pediatrics, Columbia University, New York, NY, 3Department of Medicine, Columbia University, New York, NY, 4Department of Pathology, Columbia University, New York, NY, 5Center for Computational Biology & Bioinformatics, Department of Systems Biology, Columbia University, New York, NY

    *Purpose: Patients who undergo liver transplantation for autoimmune liver disease (ALD) experience high rates of graft failure. The relative roles of recurrent ALD and rejection…
  • 2020 American Transplant Congress

    MHC II-Decoy Car-T Cells to Induce Long-Term Allotransplant Organ Tolerance

    W. McCall1, T. Baybutt1, A. Snook1, A. Shah2

    1Department of Pharmacology and Experimental Therapeutics, Sidney Kimmel Medical College, Philadelphia, PA, 2Department of Surgery, Division of Transplantation, Sidney Kimmel Medical College, Philadelphia, PA

    *Purpose: Allotransplantation represents the definitive therapy for end-stage renal, heart, liver, and lung disease. Current immunosuppressive regimens fail to promote long-term engraftment, leading to chronic…
  • 2020 American Transplant Congress

    T Cells from Highly Sensitized Kidney Transplant Patients Display Distinct TCR Repertoires

    S. Negi1, M. Li1, A. Rutman2, S. Paraskevas1, C. Polychronakos1, J. Tchervenkov1

    1RIMUHC, Montreal, QC, Canada, 2McGill University, Montreal, QC, Canada

    *Purpose: Sensitization to HLA antigens limits patient’s access to renal transplantation and causes higher risk of acute rejection and graft loss. T-cells, B-cells and donor-specific…
  • 2020 American Transplant Congress

    A Single-Cell Transcriptome Atlas of 15 Adult Human Organs

    Z. Guo1, S. He2, L. Wang1, Y. Liu2, J. Xu1, J. Bei2, X. He1

    1Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, 2The Cancer Centre of Sun Yat-Sen University, Guangzhou, China

    *Purpose: The transcriptome diversity of cell types within and across tissues is of great importance for biological function of human beings. Here we conducted a…
  • 2020 American Transplant Congress

    Pregnancy Alloimmunization Increases the Clonality of the Endogenous Treg Repertoire

    K. Krupp, E. Lewis, R. Xu, P. Porrett

    University of Pennsylvania, Philadelphia, PA

    *Purpose: Pregnancy is a common immune sensitizing event, which creates an access barrier to organ transplantation and can impact transplant outcomes. While most research has…
  • 2020 American Transplant Congress

    A Proof-of-Principle Study to Evaluate Autologous Hematopoietic Stem Cell Transplantation for Allogeneic Organ Transplant Tolerance (ASCOTT)

    A. Chruscinski1, S. Juvet1, S. Moshkelgosha1, E. Renner1, L. Lilly1, N. Selzner1, C. Bredeson2, O. Adeyi1, S. Fischer1, A. Demetris3, J. Zhang1, M. Epstein1, A. Clement2, K. Khalili1, Z. Galvin1, A. Humar1, T. Kim1, K. Tinckham1, T. Yi1, G. Levy1, H. Atkins2

    1Multi-Organ Transplantation, University Health Network, Toronto, ON, Canada, 2The Ottawa Hospital, Ottawa, ON, Canada, 3University of Pittsburgh, Pittsburgh, PA

    *Purpose: Long-term survival of recipients of solid organ transplants is limited by chronic rejection, disease recurrence and immunosuppression-induced toxicity. Self-tolerance is established after autologous hematopoietic…
  • 2019 American Transplant Congress

    Lymphotoxin Signaling Regulates T Cell Lymphatic Trafficking

    W. Piao1, L. Li2, V. Saxena2, Y. Xiong2, M. WillsonShirkey2, C. Paluskievicz2, J. Bromberg3

    1Microbiology and Immunology, U. Maryland, Baltimore, baltimore, MD, 2Surgery, U. Maryland, Baltimore, Baltimore, MD, 3Microbiology and Immunology, U. Maryland, Baltimore, Baltimore, MD

    *Purpose: Lymphotoxin (LT) α1β2 is crucial for lymphatic organ development and orchestration of immune responses. LTα1β2 is preferentially expressed by regulatory T cells (Treg) for…
  • 2019 American Transplant Congress

    Integrative Analysis of Immune Repertoire and Gene Expression from RNA-seq in Kidney Organ Transplants

    S. Pineda1, A. Ravoor2, O. Bestard3, M. Sarwal1, M. Sirota2

    1Department of Surgery, UCSF, San Francisco, CA, 2BCHSI, UCSF, San Francisco, CA, 3Department of Surgery, 3Bellvitge University Hospital, Barcelona, Spain

    *Purpose: The main problem with kidney transplantation is the possibility of rejection, which is classified as either antibody-mediated rejection (AMR) or T-cell-mediated rejection (TCMR) depending…
  • 2019 American Transplant Congress

    IE-1 Specific T Cell Receptor Repertoire Diversity and Protection against CMV Reactivation

    M. Lucia Perez1, F. Rubelt1, S. Busque1, C. O. Esquivel1, S. M. Krams1, O. Bestard2, O. M. Martinez1

    1Surgery, Stanford University School of Medicine, Stanford, CA, 2Nephrology, University of Barcelona, L'Hospitalet de Llobregat, Spain

    *Purpose: Cytomegalovirus (CMV) is a major complication for organ transplant recipients. T cells reacting to the CMV antigen immediate-early (IE-1) are key in controlling reactivation…
  • « Previous Page
  • 1
  • 2
  • 3
  • 4
  • Next Page »

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences