2017 American Transplant Congress
Transplantation of Chimeric Cells of Myoblast and Mesenchymal Stem Cell Origin for Restoration of Muscle Function.
University of Illinois at Chicago, Chicago
Background: Allogeneic stem cell therapies aim to restore muscle tissue after traumatic loss or muscular dystrophies. Limited engraftment due to rejection is a major challenge.…2017 American Transplant Congress
The Effect of Semimature Dendritic Cell on Transplantation Tolerance of Hepatocytes Differentiated from Mouse Embryonic Stem Cells.
The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
Objective Research of semimature dendritic cell(smDCs) inducing transplantation toleranceof hepatocytes differentiated from mouse embryonic stem cells (ESCs) and its mechanismtions.Methods Inducing 129 mouse ESCs labelled…2017 American Transplant Congress
Naïve and Interferon-gamma Activated Mesenchymal Stem Cells Differentially Affect Immune Responses In Vitro and In Vivo.
We have observed interferon gamma-treated autologous mesenchymal stem cells (MSC) to rapidly ex vivo expand CD3+CD4+CD25- T cells to >80% CD3+CD4+C25+FoxP3+ T regulatory cells with…2017 American Transplant Congress
Inflammatory Conditions Dictate the Effect of MSC on B Cell Function.
The immunomodulatory capacity of mesenchymal stem or stromal cells (MSC) makes them a promising therapeutic tool for immune disease and organ transplantation. The effects of…2017 American Transplant Congress
Urinary Renal Progenitors Isolation: A Novel Predictor of Kidney Graft Outcome.
1Hospital Univ Bellvitge, Barcelona, Spain; 2Meyer's Children Hosp, Firenze, Italy
Background: Longterm kidney allograft outcomes remain as unmet need. Most studies focus on mechanisms of graft injury, and kidney reparative mechanisms are neglected. Isolation of…2017 American Transplant Congress
The Delivery of Stem Cell Therapy to Extended Criteria Donor Human Livers Using Normothermic Machine Perfusion.
Normothermic machine perfusion of the liver (NMP-L) has been used for organ preservation and viability testing of donor livers. Although previously proposed, delivery of cellular…2017 American Transplant Congress
Effect of Bone Marrow Derived Mesenchymal Stem Cells on Renal Ischemia-Reperfusion Injury in Rabbit.
Background: We succeeded to set up a rabbit model of Ischemia-Reperfusion (I/R) injury to test future candidate substance or plant extract that may have anti-oxidant…2016 American Transplant Congress
Stem Cell-Mediated Regeneration of Ischemically Damaged Renal Allografts During Ex Vivo Warm Perfusion.
1BREONICS Inc., Watervliet, NY; 2Plastic Surgery, University of Utrecht, Utrecht, Netherlands.
Our goal is to address an unmet medical need by providing more kidneys for transplant. We asked 2 questions: Could a tissue-engineering platform be used…2016 American Transplant Congress
Delayed Induction of Mixed Chimerism Permits Kidney-Induced Cardiac Allograft Tolerance to be Applied to Recipients of Cadaveric Organs.
(BACKGROUND)Cardiac tolerance in nonhuman primates (NHPs) has been induced for the first time by kidney co-transplantation in combination with donor bone marrow infusion when the…2016 American Transplant Congress
c-Kit+ Cells Are Kidney-Specific Progenitor/Stem Cells with Regenerative Potential.
Introduction: Identification of progenitor/stem cell populations in mammalian tissues is important for therapeutic applications and for understanding biological processes. We recently reported that c-Kit+ cells…
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