ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Sensitization"

  • 2016 American Transplant Congress

    Frequency and Utility of Donor-Specific Antibody Testing in Simultaneous Liver Kidney Transplant.

    A. Morrison,1 D. Sawinski,2 M. Kamoun,3 P. Porrett.1

    1Surgery, University of Pennsylvania, Philadelphia, PA; 2Medicine, University of Pennsylvania, Philadelphia, PA; 3Pathology, University of Pennsylvania, Philadelphia, PA.

    Introduction: The risk of antibody mediated rejection (AMR) in simultaneous liver kidney (SLK) recipients is thought to be lower than in kidney alone patients due…
  • 2016 American Transplant Congress

    Transplanting the Extremely Sensitized Patient: The University of Wisconsin Experience with the New Kidney Allocation System.

    E. Grodstein, R. Bennett, J. Anderson, G. Press, A. Djamali, D. Kaufman, R. Redfield.

    Department of Surgery, Division of Transplantation, University of Wisconsin, Madison, WI.

    Background: The new UNOS kidney allocation system (KAS) prioritizes the transplant of highly sensitized patients with a calculated Panel Reactive Antibody (cPRA) ≥80 and extremely…
  • 2016 American Transplant Congress

    Anti-HLA Antibodies in Allogeneic and Autologous Hematopoietic Stem Cell Transplantation.

    A. Bertocchi, L. Requiao-Moura, M. Torres, E. Tonato, M. Durao Junior, A. de Matos, N. Hamershclak, A. Pacheco-Silva.

    Kidney Transplantation, Hematology, Histocompatibility Laboratory, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.

    Introduction: Anti-HLA antibodies have been associated with graft rejection in solid organ and hematopoietic stem cell transplantation (HSCT). The aim of this study was describe…
  • 2015 American Transplant Congress

    Molecular Features of Kidney Transplant Biopsies Without Allograft Injury in Relation With Type of Induction Therapy

    M. Ajaimy,1 P. O Broin,2 M. Lubetzky,1 Y. Bao,1 A. Golden,2 E. Akalin.1

    1Transplantation, Einstein/Montefiore Transplant Center, Bronx; 2Computational Genomics Facility, Albert/Einstein College of Medicine, Bronx.

    Objective: Molecular evidence of allograft injury might precede histopathological findings of allograft injury. We aimed to investigate if the type of induction therapy effect intragraft…
  • 2015 American Transplant Congress

    Characterization of Peripheral Blood T and B Cells of Sensitized Kidney Transplant Recipients With Long Term Stable Graft Function

    N. Galante,1 M. Fernandes,1 F. Agena,1 A. Triboni,1 G. Freitas,1 A. Aguirre,1 W. Nahas,1 V. Coelho,2 E. David-Neto.1

    1Renal Transplant Service, Hospital das Clínicas - University of Sao Paulo School of Medicine, Sao Paulo, Brazil; 2Laboratory of Immunology, Heart Institute - University of Sao Paulo School of Medicine, Sao Paulo, Brazil.

    We examined the phenotype of T and B cells of peripheral blood of sensitized kidney transplant recipients with stable graft function (GFR > 29mL/min) enrolled…
  • 2015 American Transplant Congress

    Eculizumab as a Rescue Therapy for Rhinovirus-Induced Antibody Mediated Rejection After Incompatible Kidney Transplantation

    E. Tantisattamo, A. Shetty, B. Ho, L. Gallon, J. Friedewald.

    Northwestern University, Chicago, IL.

    Background: Despite being an effective strategy for overcoming ABO and HLA incompatibilities, desensitized kidney transplantation still has limitations. Early antibody mediated rejection (ABMR) may be…
  • 2015 American Transplant Congress

    CPRA Values Are Substantially Increased for Some Candidates Subsequent to Inclusion of Unacceptable C-locus (UA-C) Antigens While Listing Practices Remain Unchanged

    A. Kucheryavaya,1 R. Bray,2 A. Miller,1 D. Tyan.3

    1UNOS, Richmond; 2Emory University Hospital, Atlanta; 3Stanford University, Palo Alto.

    Background: CPRA is the % of deceased donors expected to have one or more UAs with a given candidate. Prior to 12/5/13, candidates with UA-C…
  • 2015 American Transplant Congress

    Post-Kidney Allograft Nephrectomy Anti-HLA Immunization Is Not Due to a Release of Anti-HLA Antibodies from the Failed Kidney

    D. Milongo,1,3 N. Congy-Jolivet,2,3,4 A. Del Bello,1,3 F. Sallusto,5 C. Guilbeau-Frugier,6 L. Rostaing,1,3 N. Kamar.1,3

    1Department of Nephrology and Organ Transplantation, CHU Rangueil, Toulouse, France; 2Laboratoire d'Immunologie, CHU de Toulouse, Toulouse, France; 3Université Toulouse III Paul-Sabatier, Toulouse, France; 4Laboratoire d'Immunogénétique Moléculaire, EA 3034, Université Toulouse III Paul-Sabatier, Toulouse, France; 5Department of Urology, CHU Rangueil, Toulouse, France; 6Department of Histopathology, CHU Rangueil, Toulouse, France.

    Background and aims: The reasons for the increased incidence of de novo anti-HLA donor specific antibodies (DSAs) that is observed after kidney allograft nephrectomy (NTx)…
  • 2015 American Transplant Congress

    Cytomegalovirus and BK Infections in Sensitized Kidney Transplant Recipients

    S. Parajuli, B. Muth, J. Turk, M. Mohamed, D. Mandelbrot, A. Djamali.

    Department of Medicine, University of Wisconsin School of Medicine and Pubic Health, Madison.

    Background:There is little information on the incidence, risk factors and outcomes associated with cytomegalovirus (CMV) and BK infections in sensitized patientsMethods:We examined 254 kidney transplant…
  • 2015 American Transplant Congress

    What Can UNOS Data Tell Us About Patient Outcomes After Primary Renal Allograft Failure?

    A. Frank,1 A. Shah,1 P. Singh.2

    1Surgery, Thomas Jefferson University, Philadelphia, PA; 2Medicine, Thomas Jefferson University, Philadelphia, PA.

    Evidence based approaches to patient care after Renal Allograft Failure do not exist, despite this being a high mortality period. Access to retransplantation is important…
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