2019 American Transplant Congress
Single Center Deceased Donor Renal Transplant (DDRTx) Outcomes in Sensitized Patients after Implementation of the Kidney Allocation System (KAS)
Columbia University Irving Medical Center, New York, NY
*Purpose: Introduction of KAS in 2014 prioritized access to DDRTx for highly-sensitized candidates although it was unclear whether the outcomes would be acceptable in this…2019 American Transplant Congress
Transplantation of the Highly Sensitized Renal Transplant Candidate in the Post-KAS Era: Who is Left Out?
*Purpose: Highly sensitized kidney transplant candidates are given high priority under the new kidney allocation system (KAS), but it is unclear if all sensitized candidates…2019 American Transplant Congress
Could Intravenous Iron Strengthen The Chances Of Heart Transplantation For Patients With Left Ventricular Assist Devices?
*Purpose: Iron deficiency anemia (IDA) is prevalent in patients supported by left ventricular assist devices (LVADs), is associated with functional limitations, and often warrants blood…2019 American Transplant Congress
Long-Term Outcomes of Eculizumab-Treated Positive Crossmatch Recipients: Allograft Survival, Histologic Findings, and Natural History of the Donor-Specific Antibodies
*Purpose: We aimed to determine long-term outcomes for eculizumab-treated, positive crossmatch (+XM) kidney transplant recipients as compared with +XM and age-matched negative crossmatch (−XM) control…2019 American Transplant Congress
Alemtuzumab versus Antithymocyte Globulin Induction Immunosuppression in Highly Sensitized Kidney Transplant Recipients
1Tampa General Hospital, Tampa, FL, 2Florida Kidney Physicians, Tampa, FL
*Purpose: Lymphocyte depleting agents such as rabbit anti-thymocyte globulin (rATG) and alemtuzumab are used for induction in highly sensitized (PRA ≥30%) kidney transplant recipients (KTRs).…2019 American Transplant Congress
The Effects of Anti-BAFF Monoclonal Antibody in the HLA-A2 Sensitized Mouse Model
*Purpose: B-cell activating factor (BAFF) is a cytokine that plays a role in the survival, proliferation and differentiation of B-cells. The aim of this study…2019 American Transplant Congress
Outcomes of Induction Therapy with Bortezomib and High-Dose Intravenous Immunoglobulin for Kidney Transplantation with Preformed Donor-Specific Anti-Human Leukocyte Antigen Antibodies
Department of Urology, Ehime University, Toon, Japan
*Purpose: Preformed donor-specific anti-human leukocyte antigen (HLA) antibodies (DSAs) are known to increase the risk of antibody-mediated rejection (ABMR) and graft failure. However, effective methods…2019 American Transplant Congress
Decay Accelerating Factor (DAF) Regulates Germinal Center B-cell and Alloantibody Formation
*Purpose: High affinity IgG antibodies including alloantibodies result from germinal center (GC) reactions in which somatic hypermutation and positive selection cause affinity maturation. When we…2019 American Transplant Congress
Desensitization Protocols vs Kidney Paired Donation to Overcome AB0 Incompatibility and/or Donor Specific Antibodies in Living Donor Kidney Transplantation
Pancreas and Kidney Transplantation Center, University of Pisa, Pisa, Italy
*Purpose: International guidelines indicate Living Donor Kidney Transplantation (LDKT) as the best option for ESRD patients. Immunological barriers like AB0 incompatibility (AB0i) and donor specific…2019 American Transplant Congress
Epitop Matching Predicts Immunization in Kidney Transplant Recipients with Allograft Failure Leading to Worse Outcomes
*Purpose: The number of immunized patients on the waitlist is increasing worldwide. There is a lack of data about the impact of immunization after transplantation…
American Transplant Congress abstracts