2018 American Transplant Congress
Parsing the 100% CPRA Kidney Transplant Candidates, Who Gets Transplanted?
Medicine, Sacred Heart Hospital, Pensacola, FL.
Currently the United States kidney allocation system gives priority to candidates with a CPRA of 100% by giving them additional allocation points and providing national…2018 American Transplant Congress
TACI-Ig as a Desensitization Agent in a Rat Model of Antibody Mediated Rejection
We examined the effect of APRIL/BLyS blockade on B cell lineages & donor specific antibody (DSA) in preclinical rodent model as a novel desensitization strategy.…2018 American Transplant Congress
Impact of KDPI and CPRA on Outcomes in Kidney Transplant Recipients
Cedars Sinai Medical Center, Los Angeles.
Introduction: The new KAS has led to a marked increase in kidney transplants among highly sensitized recipients, mostly attributable to higher allocation of low KDPI…2018 American Transplant Congress
Donor Specific Antibodies Increase the Risk of Preeclampsia in Pregnant Kidney Transplant Recipients
Weill Cornell-New York Presbyterian, NY, NY.
Kidney transplant recipients are at an increased risk for pregnancy-associated complications including preeclampsia (PEC). Endothelial injury in the placenta is a hallmark of PEC. The…2018 American Transplant Congress
Temporal Changes in the Characteristics and Sensitization of Kidney Paired Donation Registrants
In order to utilize a willing but incompatible living donor, candidates must either proceed with incompatible transplantation or find a more compatible match using kidney…2018 American Transplant Congress
mRNA Transcript Profiling of 3 Genes in Renal Allograft Biopsies (Bx) Improves Accuracy of Antibody-Mediated Rejection (ABMR) Diagnosis in Transplant Recipients Desensitized with IVIG+Rituximab+Immunoglobulin G-Degrading Enzyme of Streptococcus Pyogenes (IdeS)
Background: Multiple molecular signatures specific to ABMR based on gene expression in renal allograft Bx of transplant recipients were reported. Here we assessed mRNA transcript…2018 American Transplant Congress
The Likelihood of Re-Transplantation in Patients Undergoing Allograft Nephrectomy
Introduction: transplant nephrectomy (NX) is a known cause of allosensitisation after graft failure. As yet, there is no consensus for the management of the patient…2018 American Transplant Congress
Mid-Term Outcome of Donor Specific Antibody Positive Deceased Donor Kidney Transplantation with Peri-Transplant Desensitization
Donor specific HLA-antibodies (DSA) remain a large barrier to successful kidney transplantation and there is a limited knowledge about desensitization strategies in deceased donor programs.Anti…2018 American Transplant Congress
Desensitization to Facilitate Matching in a Large, National Kidney Paired Exchange Clearinghouse
In kidney paired exchange (KPE) programs, the use of incompatible transplantation has been necessary to prevent long waiting times for sensitized candidates and to facilitate…2018 American Transplant Congress
Heart Transplant across Low or Moderate Level Donor-Specific Antibodies Have Acceptable Outcome
Cedars Sinai Medical Center, Los Angeles.
Purpose: The presence of pre-transplant donor specific antibodies (DSA) can reduce the likelihood of a patient (pt) obtaining a compatible donor heart. The proportion of…
American Transplant Congress abstracts