Articles tagged "Renal injury"

2020 American Transplant Congress
HMGB1 Antagonizes the Immunosuppressive Effect of MSCs in AKI
S. Cai¹, S. Wang², W. Zhang², A. Chandraker¹, C. Yang², T. Zhu²
¹Renal Division, Brigham and Women's Hospital, Boston, MA, ²Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China
*Purpose: Kidney ischemia reperfusion injury (IRI) is a common cause of acute kidney injury and an unavoidable consequence of kidney transplantation and still lacks specific…
2020 American Transplant Congress
Oral versus Intravenous Mycophenolate Mofetil Administration: A Single Center Experience on Incidence of Acute Kidney Injury
P. Chung¹, K. Forrester², S. Ganesh¹
¹Division of Pulmonary Critical and Sleep Medicine, University of Southern California, Los Angeles, CA, ²Department of Clinical Pharmacy, University of Southern California School of Pharmacy, Los Angeles, CA
*Purpose: Mycophenolate mofetil (MMF) is one of the main immunosuppressive medications given in lung transplantation (LTx). It is given orally (PO) or intravenously (IV). In…
2020 American Transplant Congress
The Role of CXCL16/CXCR6 in Mediating Macrophage Chemotaxis and M1 Macrophage Polarization in Murine Renal Ischemia Reperfusion Injury
W. Zhang¹, X. Zhang², G. Tu², C. Yang¹, G. Qi¹, M. Xu¹, T. Zhu¹
¹Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China, ²Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China
*Purpose: The objective of this study is to investigate the role of Chemokine (C-X-C motif) ligand 16 (CXCL16) and its unique receptor C-X-C chemokine receptor…
2020 American Transplant Congress
Acute Kidney Injury And Chronic Kidney Disease After Lung Transplantation: Incidence And Risk Factors In A Large Single-center Cohort
D. Abdelwahab, R. Marron, Z. Choudhry, I. Lee, J. Wu, J. Brown
Lewis Katz School of Medicine, Temple University, Philadelphia, PA
*Purpose: Chronic kidney disease (CKD) is a common complication after lung transplant. The reported incidence in small studies varies ranges from10-90%. Furthermore, data on risk…
2020 American Transplant Congress
Value of dd-cfDNA When Considering Recipient Ethnicity to Further to Help Risk Stratify Transplant Recipients
A. Langone¹, B. Fischbach², D. Cohen³
¹Vanderbilt Health, Nashville, TN, ²Baylor Scott & White Health, Fort Worth, TX, ³Columbia University, New York, NY
*Purpose: Within the modern era of kidney transplantation, African American (AA) transplant recipients continue to experience disproportionately higher rates of allograft loss. A combination of…
2020 American Transplant Congress
Mir-124/ire-1α Affects Renal Ischemia/Reperfusion Injury by Regulating Endoplasmic Reticulum Stress in Renal Tubularepithelial Cells
C. Ding, W. Xue
Department of Renal Transplantation, The First Affiliated Hospital of Xi’an Jiaotong University, Xi'an, China
*Purpose: In this study, we investigated the protective functions of miR-124 on renal I/R injury both in vivo and in vitro and explored its underlying…
2020 American Transplant Congress
Delayed Graft Function Predicts High Risk of Allograft Loss Following Living and Deceased Donor Pediatric Kidney Transplantation
M. MacConmara¹, J. Gattineni¹, D. Desai¹, J. Parekh², P. Vagefi¹, C. S. Hwang¹
¹UT Southwestern, Dallas, TX, ²UC San Diego, San Diego, CA
*Purpose: Pediatric kidney recipients receive high quality living and deceased donor kidneys for transplantation, and as such, these kidneys have a low rate of delayed…
2020 American Transplant Congress
Perioperative Predictors of Acute Kidney Injury among Liver Transplant Recipients
R. Berkowitz¹, N. Douville², G. Mentz², P. Sharma³, C. Sonnenday¹
¹Surgery, Michigan Medicine, Ann Arbor, MI, ²Anesthesiology, Michigan Medicine, Ann Arbor, MI, ³Gastroenterology, Michigan Medicine, Ann Arbor, MI
*Purpose: We examined the perioperative and intraoperative risk factors associated with post-operative acute kidney injury (AKI) at post-op 7 days and 30-day estimated glomerular filtration…
2020 American Transplant Congress
Intraoperative Oxygen Delivery and Acute Kidney Injury after Liver Transplantation
W. Kim, H. Lee, H. Yoon, K. Suh
Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea, Republic of
*Purpose: Although intraoperative hemodynamic variables were reported to be associated with acute kidney injury (AKI) after liver transplantation, the time-dependent association between intraoperative oxygen delivery…
2020 American Transplant Congress
Improved Kidney Function Post Lung Transplant with Intravenous Tacrolimus Avoidance
C. Burt¹, A. Feist¹, K. Afshar², L. Awdishu¹, M. Mariski¹, J. Kozuch¹, G. Yung², E. Golts³
¹Pharmacy, UC San Diego Health, San Diego, CA, ²Pulmonology, UC San Diego Health, San Diego, CA, ³Cardiothoracic Surgery, UC San Diego Health, San Diego, CA
*Purpose: Tacrolimus (TAC) poses a dose-dependent risk of acute kidney injury (AKI) as well as chronic kidney disease (CKD) post-transplant. In 2017, our institution’s lung…

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