ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Renal injury"

  • 2020 American Transplant Congress

    Intraoperative Oxygen Delivery and Acute Kidney Injury after Liver Transplantation

    W. Kim, H. Lee, H. Yoon, K. Suh

    Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea, Republic of

    *Purpose: Although intraoperative hemodynamic variables were reported to be associated with acute kidney injury (AKI) after liver transplantation, the time-dependent association between intraoperative oxygen delivery…
  • 2020 American Transplant Congress

    Improved Kidney Function Post Lung Transplant with Intravenous Tacrolimus Avoidance

    C. Burt1, A. Feist1, K. Afshar2, L. Awdishu1, M. Mariski1, J. Kozuch1, G. Yung2, E. Golts3

    1Pharmacy, UC San Diego Health, San Diego, CA, 2Pulmonology, UC San Diego Health, San Diego, CA, 3Cardiothoracic Surgery, UC San Diego Health, San Diego, CA

    *Purpose: Tacrolimus (TAC) poses a dose-dependent risk of acute kidney injury (AKI) as well as chronic kidney disease (CKD) post-transplant. In 2017, our institution’s lung…
  • 2020 American Transplant Congress

    microRNA-223 in MSCS-Derived Exosomes Protects Against Renal Ischemia/Reperfusion Injury Through Inhibiting Pyroptosis Pathway via Directly Targeting NLRP3

    C. Ding, W. Xue

    Department of Renal Transplantation, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China

    *Purpose: miR-223 is a well-studied miRNA that has been tested for abnormal expression in many diseases, and it has been found to play a regulatory…
  • 2020 American Transplant Congress

    Understanding the Molecular Phenotype of Kidney Injury

    J. Reeve1, P. Halloran1, &. the INTERCOMEX Study Group2

    1University of Alberta, Edmonton, AB, Canada, 2., ., AB, Canada

    *Purpose: The injury status of transplanted organs is a strong predictor of graft loss. We used injury-related gene expression to explore the relationship between function,…
  • 2020 American Transplant Congress

    Effect of Hepatic Steatosis on Hepatic Ischemia-Reperfusion Induced Acute Kidney Injury in Mice

    T. Nikumbh1, N. Biswas2, A. Das2, C. K. Sen2, S. Kubal1

    1Transplant Surgery, Indiana University School of Medicine, Indianapolis, IN, 2ICRME, Indiana University School of Medicine, Indianapolis, IN

    *Purpose: Livers with mild to moderate steatosis have been used to expand the donor pool for transplantation. However, livers with steatosis have a propensity for…
  • 2020 American Transplant Congress

    Three Year Post Co-Stimulation Blocking Agent (Belatacept) Switch Outcomes of Kidney Transplant Patients Diagnosed with Post-Transplant Thrombotic Microangiopathy

    A. Gamilla-Crudo, S. Hussain, A. Rizvi, R. Ramirez, M. Kueht, H. Stevenson-Lerner, J. Fair, M. Mujtaba

    UTMB, Galveston, TX

    *Purpose: Thrombotic microangiopathy (TMA) can happen after kidney transplant. It may occur de novo or as a recurrent disease. De novo is usually associated with…
  • 2020 American Transplant Congress

    ANG-3777 Treatment Attenuates Ischemia-Reperfusion-Induced Renal Injury in Rat and Dog Models

    P. Narayan1, M. Mangino2, I. D. Goldberg1

    1Angion Biomedica, Uniondale, NY, 2Virginia Commonwealth University, Richmond, VA

    *Purpose: The effect of ANG-3777, a small-molecule mimetic of hepatocyte growth factor, was evaluated on reducing ischemia-reperfusion-induced renal injury and mortality in rats and dogs…
  • 2020 American Transplant Congress

    Gasdermin-D Mutation is Protective against Renal Ischemia Reperfusion Injury

    J. Li, N. Rogers, S. Alexander

    Centre for Transplant and Renal Research, Westmead Institute for Medical Research, Westmead, Australia

    *Purpose: Pyroptosis, a pro-inflammatory form of cell death, is dependent on membrane pore formation through the assembly of cleaved Gasdermin-D molecules. We hypothesized that this…
  • 2020 American Transplant Congress

    Zoledronate Induced AKI with Nephrotic Range Proteinuria in a Transplant Kidney

    S. Reddy, H. Khamash

    Nephrology, Mayo Clinic, Phoenix, AZ

    *Purpose: An unusual presentation of acute kidney injury with nephrotic range proteinuria following zoledronate in a normal functioning transplant kidney.*Methods: 61-year-old lady with history of…
  • 2020 American Transplant Congress

    Kidneys from AKI Donors with Poor Long-Term Outcomes Present an Impaired Protein Expression for Cellular Stress and Repair

    F. Neri1, M. Lo Faro1, C. Boffa1, T. Surik1, M. Kaisar1, E. J. Sharples2, J. P. Hunter1, J. Lindeman3, R. Ploeg1

    1Nuffield Department of Surgical Sciences, Oxford University, Oxford, United Kingdom, 2Oxford Transplant Centre, Oxford, United Kingdom, 3Department of Vascular Surgery, Leiden University Medical Center (LUMC), Leiden, Netherlands

    *Purpose: The utilization of kidneys from donors with acute kidney injury (AKI) is often limited by unpredictable post-transplantation outcomes. The aim of our study was…
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