2021 American Transplant Congress
Combining Oxygenated Cold Perfusion with Normothermic Ex-vivo Perfusion Improves the Outcome of DCD Porcine Kidney Transplantation
*Purpose: Ex-vivo machine perfusion is a novel preservation technique for the storage and assessment of marginal kidney grafts. Normothermic (NEVKP) as well as hypothermic machine…2020 American Transplant Congress
Improved Kidney Function Post Lung Transplant with Intravenous Tacrolimus Avoidance
*Purpose: Tacrolimus (TAC) poses a dose-dependent risk of acute kidney injury (AKI) as well as chronic kidney disease (CKD) post-transplant. In 2017, our institution’s lung…2020 American Transplant Congress
microRNA-223 in MSCS-Derived Exosomes Protects Against Renal Ischemia/Reperfusion Injury Through Inhibiting Pyroptosis Pathway via Directly Targeting NLRP3
*Purpose: miR-223 is a well-studied miRNA that has been tested for abnormal expression in many diseases, and it has been found to play a regulatory…2020 American Transplant Congress
Understanding the Molecular Phenotype of Kidney Injury
1University of Alberta, Edmonton, AB, Canada, 2., ., AB, Canada
*Purpose: The injury status of transplanted organs is a strong predictor of graft loss. We used injury-related gene expression to explore the relationship between function,…2020 American Transplant Congress
Effect of Hepatic Steatosis on Hepatic Ischemia-Reperfusion Induced Acute Kidney Injury in Mice
*Purpose: Livers with mild to moderate steatosis have been used to expand the donor pool for transplantation. However, livers with steatosis have a propensity for…2020 American Transplant Congress
Three Year Post Co-Stimulation Blocking Agent (Belatacept) Switch Outcomes of Kidney Transplant Patients Diagnosed with Post-Transplant Thrombotic Microangiopathy
*Purpose: Thrombotic microangiopathy (TMA) can happen after kidney transplant. It may occur de novo or as a recurrent disease. De novo is usually associated with…2020 American Transplant Congress
ANG-3777 Treatment Attenuates Ischemia-Reperfusion-Induced Renal Injury in Rat and Dog Models
1Angion Biomedica, Uniondale, NY, 2Virginia Commonwealth University, Richmond, VA
*Purpose: The effect of ANG-3777, a small-molecule mimetic of hepatocyte growth factor, was evaluated on reducing ischemia-reperfusion-induced renal injury and mortality in rats and dogs…2020 American Transplant Congress
Gasdermin-D Mutation is Protective against Renal Ischemia Reperfusion Injury
*Purpose: Pyroptosis, a pro-inflammatory form of cell death, is dependent on membrane pore formation through the assembly of cleaved Gasdermin-D molecules. We hypothesized that this…2020 American Transplant Congress
Zoledronate Induced AKI with Nephrotic Range Proteinuria in a Transplant Kidney
Nephrology, Mayo Clinic, Phoenix, AZ
*Purpose: An unusual presentation of acute kidney injury with nephrotic range proteinuria following zoledronate in a normal functioning transplant kidney.*Methods: 61-year-old lady with history of…2020 American Transplant Congress
Kidneys from AKI Donors with Poor Long-Term Outcomes Present an Impaired Protein Expression for Cellular Stress and Repair
*Purpose: The utilization of kidneys from donors with acute kidney injury (AKI) is often limited by unpredictable post-transplantation outcomes. The aim of our study was…
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