2021 American Transplant Congress
Hypercholesterolemia and Donor Age Impaired Capillary Vegf and Nitric Oxide (no) Expression and in Turn Decrease Both Microvascular Density and Tubule Villin Expression in Renal Allografts, Resulting in Poor Graft Survival
*Purpose: The role of aging and hypercholesterolemia (HC) on endothelial cells (ECs) are not well defined. Aged ECs might produce less NO and VEGF, resulting…2021 American Transplant Congress
Development of Novel Multivariable Logistic Regression Model for Predicting Acute Kidney Injury After Liver Transplantation
Organ Transplant Center,, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: Acute kidney injury (AKI) is a common early complication after liver transplantation, but there are no related predictive tools or models at present. The…2021 American Transplant Congress
Perioperative Terlipressin Therapy Reduces the Risk of Acute Kidney Injury Post-Living Donor Liver Transplantation – A Systematic Review and Meta-analysis
Hepatology and Liver Transplantation, Asian Institute of Gastroenterology, Hyderabad, India
*Purpose: Acute kidney injury (AKI) after liver transplantation precludes calcineurin inhibitors' therapy and is associated with poor outcomes. Terlipressin (Tp) has mortality benefit in pre-transplant…2021 American Transplant Congress
Acute Kidney Injury After Lung Transplantation: Incidence, Risk Factors and Outcomes. Results from a Monocentric Retrospective Cohort Study
*Purpose: Acute kidney Injury (AKI) occurs in more than 50% of patients after lung transplantation (LTx). Our purpose was to define incidence, risk factors and…2021 American Transplant Congress
Kidney Transplant Biopsy Findings After Covid-19
*Purpose: COVID-19 has been reported as a cause of kidney injury and data from published native kidney biopsy results demonstrate a variety of causes. To…2021 American Transplant Congress
Mapping Chronic Kidney Disease (CKD) and Acute Kidney Injury (AKI) in Kidney Transplant Biopsies Reveals Two Classes of Early AKI That Differ in Their Response-to-Wounding
*Purpose: We recently analyzed injury-induced molecular changes in kidney transplant biopsies using principal component analysis (PCA) (AJT https://doi.org/10.1111/ajt.16374). PC1 reflected all injury, PC2 distinguished early…2021 American Transplant Congress
Inflammation in Scarred Cortex (i-IFTA) is Significantly Associated with T Cell-mediated Rejection (TCMR), but Not Antibody-mediated Rejection (ABMR), in Renal Allograft Biopsies (Bx)
Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: I-IFTA in renal allograft Bx has been found to be associated with decreased death-censored graft survival. Moderate to severe i-IFTA (2 or 3) is…2021 American Transplant Congress
Late Subclinical Rejection and Borderline Rejection in Kidney Transplant Patients is Associated with Increased Incidence of Subsequent Clinical Rejections
*Purpose: The outcomes of inflammatory changes noted in late surveillance biopsies (1 year) is unclear.*Methods: Patients transplanted (live donor and deceased donor) at our center…2021 American Transplant Congress
Pathways and Factors That Confer Therapeutic Properties of Adipose Derived Regenerative Cells in Reducing Ischaemia Reperfusion Injury in Kidney Transplantation
Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom
*Purpose: Studies in our rat model of ischemic reperfusion injury (IRI) demonstrate improved kidney function post injection of non-cultured autologous adipose-derived regenerative cells (ADRC). The…2021 American Transplant Congress
Donor Kidney-Resident Macrophages Promote Allograft Inflammation and CD8 T Cell Response Post-Transplantation
*Purpose: Kidney-resident macrophages play important roles in maintaining normal kidney function and promoting prompt repair following kidney injuries. Nevertheless, their fate and role in kidney…
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