ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Renal injury"

  • 2022 American Transplant Congress

    Technical Report to Increased Utilization of Injured Kidneys: CT Scan to Evaluate Organ and Reduce Discard

    V. E. Whittaker

    Surgery, Columbia Vagelos College of Physicians and Surgeons, New York, NY

    *Purpose: To reduce discard of injured kidneys with parenchymal injury or perinephric hematoma . Young donors with good function but injury are at high risk…
  • 2022 American Transplant Congress

    Anti-Fibrotic Property of Adipose Derived Regenerative Cells on Hydrogen Peroxide Induced Injury in Nrk-52e Cells

    R. Chawangwongsanukun1, R. Lathan1, R. Pearson2, M. Clancy2, P. Mark1

    1Institute of Cardiovascular and Medical Sciences, Glasgow, United Kingdom, 2Transplant Unit, Queen Elizabeth University Hospital, Glasgow, United Kingdom

    *Purpose: Adipose derived regenerative cells (ADRCs) are a heterogenous cell population derived from adipose tissue. These cells are composed of endothelial progenitor cells, pericytes, and…
  • 2022 American Transplant Congress

    Kidney Nonprocurement in Deceased Donors with Acute Kidney Injury

    K. Yu1, K. King1, S. Husain1, J. Stevens1, C. Parikh2, S. Mohan1

    1Division of Nephrology, Columbia University Medical Center, New York, NY, 2Division of Nephrology, Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: Deceased donor acute kidney injury (AKI) is associated with high rates of kidney discard by transplant centers, despite evidence of excellent post-transplant outcomes. High…
  • 2022 American Transplant Congress

    DCD and AKI Kidneys Experiencing DGF as a Platform for the Study of Adaptive Repair

    B. Bussolati1, S. Da Sacco2, A. Asthana3, L. N. Byers3, L. Perin4, M. S. Garner3, B. Sharda3, A. C. Farney3, C. J. Jay3, R. J. Stratta3, S. J. Walker5, G. Orlando3

    1University of Turin, Turin, Italy, 2Children Hospital Los Angeles, Los Angeles, NC, 3Wake Forest Baptist Medical Center, Winston-Salem, NC, 4Children Hospital Los Angeles, Los Angeles, CA, 5WFIRM, Winston-Salem, NC

    *Purpose: AKI and DCD renal allografts are at high risk for DGF, yet the majority of these kidneys will eventually recover and attain good function…
  • 2022 American Transplant Congress

    Diagnosis of Acute Graft Rejection After Kidney Transplantation Using Metabolome Analysis by Liquid Biopsy Approach

    H. Iwamoto1, O. Konno1, Y. Kihara1, M. Okihara1, I. Akashi1, T. Ueno1, M. Sugimoto2

    1Department of Kidney Transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan, 2Research and Development Center for Minimally Invasive and Preemptive Medicine, Tokyo Medical University, Tokyo, Japan

    *Purpose: Presently, a definitive diagnosis of organ dysfunction after transplantation (such as acute rejection) is dependent on conventional histopathological evaluation using an invasive biopsy procedure…
  • 2021 American Transplant Congress

    Acute Kidney Injury After Lung Transplantation: Incidence, Risk Factors and Outcomes. Results from a Monocentric Retrospective Cohort Study

    M. Gandolfo1, C. Bellincioni1, L. Morlacchi2, V. Rossetti2, F. Blasi2, P. Messa1

    1Nephrology, Ospedale Maggiore Policlinico, Milano, Italy, 2Pneumology, Ospedale Maggiore Policlinico, Milano, Italy

    *Purpose: Acute kidney Injury (AKI) occurs in more than 50% of patients after lung transplantation (LTx). Our purpose was to define incidence, risk factors and…
  • 2021 American Transplant Congress

    Kidney Transplant Biopsy Findings After Covid-19

    E. Daniel1, S. Kudose2, D. J. Cohen1, L. Ratner3, V. D'Agati2, I. Batal2

    1Division of Nephrology, Columbia University Medical Center, NY, NY, 2Department of Pathology, Columbia University Medical Center, NY, NY, 3Department of Surgery, Columbia University Medical Center, NY, NY

    *Purpose: COVID-19 has been reported as a cause of kidney injury and data from published native kidney biopsy results demonstrate a variety of causes. To…
  • 2021 American Transplant Congress

    Mapping Chronic Kidney Disease (CKD) and Acute Kidney Injury (AKI) in Kidney Transplant Biopsies Reveals Two Classes of Early AKI That Differ in Their Response-to-Wounding

    P. Halloran1, J. Reeve1, G. Böhmig2, O. Viklicky3, M. Myslak4, G. Gupta5, &. the INTERCOMEX Study Group6

    1Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 2Medical University of Vienna, Vienna, Austria, 3Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 4Pomeranian Medical University, Szczecin, Poland, 5Virginia Commonwealth University, Richmond, VA, 6., ., AB, Canada

    *Purpose: We recently analyzed injury-induced molecular changes in kidney transplant biopsies using principal component analysis (PCA) (AJT https://doi.org/10.1111/ajt.16374). PC1 reflected all injury, PC2 distinguished early…
  • 2021 American Transplant Congress

    Inflammation in Scarred Cortex (i-IFTA) is Significantly Associated with T Cell-mediated Rejection (TCMR), but Not Antibody-mediated Rejection (ABMR), in Renal Allograft Biopsies (Bx)

    H. Zhang

    Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: I-IFTA in renal allograft Bx has been found to be associated with decreased death-censored graft survival. Moderate to severe i-IFTA (2 or 3) is…
  • 2021 American Transplant Congress

    Late Subclinical Rejection and Borderline Rejection in Kidney Transplant Patients is Associated with Increased Incidence of Subsequent Clinical Rejections

    V. Viswanathan1, I. Melgarejo2, C. Puttarajappa2, P. Sood2, M. Molinari2, S. Hariharan2, C. Wu2, A. Sharma2, N. Shah2, R. Mehta2

    1Department of Medicine, Renal-Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, PA, 2Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: The outcomes of inflammatory changes noted in late surveillance biopsies (1 year) is unclear.*Methods: Patients transplanted (live donor and deceased donor) at our center…
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