2017 American Transplant Congress
The Treatment of the Graft and the Recipient with α-Lipoic Acid Improves the Delay Graft Function Severity in the Human Kidney Transplant.
A previous pilot clinic trial had showed that treatment of the donor and recipient with a potent anti-oxidant such as α-lipoc acid (ALA) reduces the…2017 American Transplant Congress
Protective Effect of New Delivery System of Nitric Oxide Releasing Nanofiber in Rat Model of Renal Ischemia-Reperfusion Injury.
Objective: Renal ischemia-reperfusion injury (IRI) is very important in various clinical setting including kidney transplantation. Nitric oxide (NO) is well known for having various protective…2017 American Transplant Congress
Efficacy of Calcineurin Inhibitors Transferring to Rapamycin in Live Kidney Transplantation from Old Donors to Young Recipients.
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Background Calcineurin inhibitor(CNI) nephrotoxicity is one of the major reasons for chronic allograft injury in live kidney transplantation from old donors to young recipients. Therefore…2017 American Transplant Congress
Pre-OLT CKD-3 Increases Post-OLT ESRD and AKI Impacts Early Post-OLT Survival.
Recanati Miller Transplant Institute, Icahn School of Medicine at Mount Sinai, Irvington, NY
Current combined Liver-kidney allocation protocols allocate dual organs based on sustained glomerular filtration rates (eGFR) of 30ml/min or less. It is unclear whether milder renal…2017 American Transplant Congress
The Degree of NK Cell Activation Determines the Ability of Donor-Specific Antibodies to Mediate Acute vs. Chronic Rejection of Kidney Allografts.
While the incidence of antibody-mediated kidney graft rejection has increased, the key cellular and molecular participants underlying this graft injury remain unclear. We have previously…2017 American Transplant Congress
A Humanized Anti-CD47 Monoclonal Antibody Therapy Alleviates Ischemia-Reperfusion Injury of Porcine Renal Allografts Donated After Cardiac Death.
PURPOSE: This study investigated whether the blockade of the CD47 signaling pathway, which is involved in vascular endothelial nitric oxide regulation, reduces ischemia-reperfusion injury (IRI)…2017 American Transplant Congress
Hepatic Ischemia Reperfusion Injury After Liver Transplantation Is Associated with Acute Kidney Injury.
Background: The impact of liver allograft ischemia/reperfusion injury (IRI) on native renal function remains to be characterized. We hypothesized that severity of IRI correlates with…2016 American Transplant Congress
Deceased Donor Urine C5a Predicts Donor and Recipient Acute Kidney Injury.
Anti-complement therapies are currently being tested in human kidney transplantation to prevent DGF. In this large prospective, cohort study of 469 deceased organ donors, we…2016 American Transplant Congress
Many Discarded Kidneys Are Similar to Kidneys Accepted for Transplantation as Judged by Their Histologic Lesions and Molecular AKI Scores.
There is an increase in the number kidneys from older brain dead donors (DBD). Many are discarded based on conventional features (clinical or histology). Thus…2016 American Transplant Congress
Influence of AKIN Stage on the Outcome of Deceased Donor Kidney Transplantation (DDKTx).
BackgroundTransplanting kidneys from donors with AKI is one of the methods to minimize the disparity between numbers of listed patient and donor pool. Our aim…
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