Articles tagged "Renal function"

2022 American Transplant Congress
Adherence, Outcomes and Adverse Effects in Pediatric Renal Transplant Patients After Early Steroid-Withdrawal and Low-Dose Calcineurin Inhibitor Maintenance Immunosuppression
A. Garcia¹, R. Plews¹, M. Moran¹, F. Trujillo¹, A. Martinez¹, N. Koizumi², D. Conti¹, J. Ortiz¹
¹Albany Medical College, Albany, NY, ²George Mason University, Arlington, VA
*Purpose: To explore adherence and long-term impacts of a sirolimus-based, low-dose calcineurin inhibitor regimen with early steroid withdrawal in pediatric renal transplant recipients.*Methods: A single-center,…
2022 American Transplant Congress
Diabetes Mellitus and Blood Glucose Variability Increases the 30-day Readmission Rate After Kidney Transplantation
H. Chakkera¹, C. Cook¹, S. Saghafian², A. Orfanoudaki³
¹Mayo Clinic Arizona, Scottsdale, AZ, ²Harvard University, Boston, MA, ³University of Oxford, Oxford, United Kingdom
*Purpose: The 30-day readmission rate is a surrogate metric of quality of care and mortality after kidney transplantation. Diabetes and observations of glucose variability during…
2022 American Transplant Congress
Dual Therapy with Esculin and Erythropoietin Attenuates Renal Ischemia-Reperfusion Injury via P2x7 Receptor and Nlrp3 Inflammasome Inhibition, and Pi3k/akt Activation
E. Hafiz¹, W. H. El-Maadawy², M. Hassan³, M. H. Badawy⁴, S. Eldahshan⁴, A. AbuSeada⁵
¹Clinical Research Laboratory Department, Theodor Bilharz Research Institute, Giza, Egypt, ²Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt, ³Immunology Department, Theodor Bilharz Research Institute, Giza, Egypt, ⁴Urology Department, Theodor Bilharz Research Institute, Giza, Egypt, ⁵Anesthesia Department, Theodor Bilharz Research Institute, Giza, Egypt
*Purpose: Renal ischemia/reperfusion (RI/R) is an inevitable condition during renal transplantation with critical clinical outcomes. Accordingly, effective therapies are crucially required.*Methods: In this study, the…
2022 American Transplant Congress
Outcome of Pre-Emptive Kidney Transplantation in Children Under 6 Years of Age; A Single Center Experience in Japan
Y. Aoki¹, Y. Hamasaki¹, J. Hashimoto¹, A. Zaitsu², M. Kubota¹, M. Muramatsu¹, T. Kawamura¹, S. Shishido², K. Sakai¹
¹Nephrology, Toho University Faculty of Medicine, Tokyo, Japan, ²Pediatric Nephrology, Toho University Faculty of Medicine, Tokyo, Japan
*Purpose: Kidney transplantation (KT) is the preferred treatment for pediatric end stage renal disease, and pre-emptive kidney transplantation (PEKT) may reduce morbidity and mortality. KT…
2022 American Transplant Congress
The Renin Angiotensin System (RAS) After Pig-to-Baboon Kidney Transplantation
C. Hansen-Estruch¹, M. H. Bikhet¹, M. Javed¹, D. Ayares², A. Katsurada³, R. Satou³, W. Shao³, D. K. Cooper¹, L. G. Navar³, E. Judd⁴
¹Surgery, University of Alabama at Birmingham, Birmingham, AL, ²Revivicor, Blacksburg, VA, ³Department of Physiology and Hypertension and Renal Center, Tulane University, New Orleans, LA, ⁴Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL
*Purpose: Relatively long-term survival after life-supporting pig-to-baboon kidney transplantation has been achieved. However, there are documented episodes of hypovolemia during the post-transplant period from an…
2022 American Transplant Congress
Basiliximab Provides Similar Efficacy and Renal Recovery in Steroid-Minimal Liver Transplantation
L. Bowman¹, A. Webb¹, Y. Alsalihi², F. Fakhre³, R. Baliga⁴, V. Subramanian⁵, K. Robichaux³, S. Mohammed³, M. Gosselin⁶, J. Buggs⁵, A. Kumar⁷
¹Transplant Pharmacy, Tampa General Hospital, Tampa, FL, ²California Health Sciences University, Clovis, CA, ³University of South Florida, Tampa, FL, ⁴Florida Kidney Physicians, Tampa, FL, ⁵Transplant Surgery, Tampa General Hospital, Tampa, FL, ⁶University of Tampa, Tampa, FL, ⁷Morsani College of Medicine, University of South Florida, Tampa, FL
*Purpose: Due to nephrotoxic effects of tacrolimus, previous studies have evaluated the utility of basiliximab to delay or reduce tacrolimus for renal preservation in orthotopic…
2022 American Transplant Congress
De Novo Lipoprotein-X Causing Hypercholesterolemia and Acute Kidney Injury (AKI) in Simultaneous Liver Kidney Transplant (SLKT) Patient
H. Me, S. S. Nair, M. Al-Qaisi, M. Ryan, L. Kodali, B. Aqel
Mayo Clinic, Phoenix, AZ
*Purpose: Cholestasis can cause reflux and spillage of biliary lipid into the plasma which can combine with albumin forming lipoprotein-X. Severe hypercholesterolemia mediated by lipoprotein-X…
2022 American Transplant Congress
Renal Function After Orthotopic Liver Transplantation
N. Kemmer¹, z. Alam², S. Desai³, L. Grater⁴, K. Robichaux⁵, S. Mohammed⁵, M. Gosselin⁴, A. Kumar⁶, J. Buggs⁷
¹Transplant Hepatology, Tampa General Hospital, Tampa, FL, ²Lake Erie College of Osteopathic Medicine, Bradenton, FL, ³Western University of Osteopathic Medicine, Pomona, CA, ⁴University of Tampa, Tampa, FL, ⁵University of South Florida, Tampa, FL, ⁶Morsani College of Medicine, University of South Florida, Tampa, FL, ⁷Transplant Surgery, Tampa General Hospital, Tampa, FL
*Purpose: Patients with end-stage liver disease are susceptible to renal dysfunction especially during liver transplantation (LTX). Continuous renal replacement therapy (CRRT) can be used to…
2022 American Transplant Congress
Early Experience Of 48-hour Normothermic Machine Perfusion In Human Kidneys Applying Urine Recirculation
F. Messner¹, S. Gasteiger¹, M. Pühringer-Sturmayr¹, A. Soleiman¹, D. Öfner¹, S. Schneeberger¹, A. Weissenbacher²
¹Medical University of Innsbruck, Innsbruck, Austria, ²Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria
*Purpose: Normothermic machine perfusion (NMP) of the kidney has been studied extensively during the past decade. Short-term kidney NMP has demonstrated promising results, however currently…
2022 American Transplant Congress
Evolution of Donor-Derived Cell-Free DNA During the First Week After Surgery Predicts Renal Function Recovery After Kidney Transplantation
D. Cucchiari¹, E. Cuadrado¹, E. Gonzalez¹, J. Puig¹, M. Ramirez-Bajo¹, P. Ventura-Aguiar¹, I. Revuelta², B. Bayès¹, F. Diekmann¹
¹Hospital Clínic de Barcelona, Barcelona, Spain, ²Hospital Clinic de Barcelona, Barcelona, Spain
*Purpose: Donor-derived cell-free DNA (ddcfDNA) is usually employed starting from the second week after kidney transplantation (KT), as its earlier increase can be due to…