2016 American Transplant Congress
Pre-Formed AT1R Antibodies Are Associated with Rejection After Kidney Transplantation.
Nephrology, University of Washington, Seattle.
Antibody mediated injury is a significant contributor to rejection and allograft damage. Non-HLA antibodies have been increasingly recognized in association with graft dysfunction. Our goal…2016 American Transplant Congress
The Impact of Allograft Rejection on DNA Methylation After Kidney Transplantation.
ErasmusMC, University Medical Center Rotterdam, Rotterdam, Netherlands.
Introduction DNA methylation is a well-known epigenetic mechanism which plays a critical role in cell function by regulating gene expression. Variations in DNA methylation are…2016 American Transplant Congress
Bile Acid Signaling Affects Metabolism and Prolongs Allograft Survival in Obese Recipients.
Although obesity has been linked to impaired transplant outcomes, underlying mechanisms and consequences of obesity on alloimmunity are only poorly understood.Allogenic skin transplantations were performed…2016 American Transplant Congress
Susceptibility Patterns of Pre-Transplant Pseudomonas and Post-Lung Transplant Outcomes in Patients with Cystic Fibrosis.
Background: The impact of pre-lung transplant (LT) pan-drug-resistant Pseudomonas aeruginosa (PDR PsA) colonization on post-LT mortality and bronchiolitis obliterans syndrome (BOS) rates in cystic fibrosis…2016 American Transplant Congress
Treatment of Late Antibody-Mediated Rejection: Observations from Clinical Practice.
Antibody-mediated rejection (AMR) is a major cause of late renal allograft failure. The benefit of treatment of chronic ABMR is unknown. Currently there is no…2016 American Transplant Congress
Kidney Transplant with Low Level DSA and Low Positive B-Flow Crossmatch: An Underappreciated Option for Highly Sensitized Transplant Candidates.
Transplant Center, Mayo Clinic, Rochester, MN.
Introduction: Avoiding DSA is difficult in sensitized patients. A kidney transplant (KTx) with low level DSA with or without a low level B flow cytometric…2016 American Transplant Congress
Long Term Outcomes Following Antibody Mediated Rejection (AMR) in Renal Transplant Recipients.
Columbia University, New York.
INTRO: Progress in AMR treatment has improved early graft survival. Since the new kidney allocation system results in more sensitized patients getting transplanted, we expect…2016 American Transplant Congress
The Effect of Maternal Graft in Early Acute Cellular Rejection After Pediatric Living Donor Liver Transplantation.
Objectives: It has been reported that the living donor liver transplantation (LDLT) in which the patients received a maternal graft could be more successful compared…2016 American Transplant Congress
Development and Validation of a Molecular Microscope Diagnostic System (MMDx) for Heart Transplant Biopsies.
The diagnosis of heart transplant rejection by histology in endomyocardial biopsies (EMB) is challenging. A molecular system (MMDx) has been developed to assess both T…2016 American Transplant Congress
Role of NRP1 in CD4+ T Cell Allo-Activation.
Department of Surgery, Boston Children's Hospital, Boston, MA.
Introduction: Neuropilin-1 (NRP1) is a transmembrane glycoprotein that functions as a co-receptor for class III/IV semaphorins, VEGF, and several other growth factors. NRP1 has been…
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