2016 American Transplant Congress
Influence of Inclusion of the Liver on the Outcome After Intestinal Transplantation.
1Abdominal Transplantation, UZ Leuven, Leuven, Belgium; 2Pathology, UZ Leuven, Leuven, Belgium.
Introduction: Intestinal transplantation (ITx) is indicated when life-threatening complications occur following chronic total parenteral nutrition in intestinal failure patients. Several complications (TPN related irreversible liver…2016 American Transplant Congress
Acute Rejections and Incidence of De Novo DSA Depend on Donor Factors and Deceased Donor Kidney Associated Risk Assessed by the Kidney Donor Profile Index (KDPI).
Nephrology, Charite, Berlin, Germany.
Introduction: Little data exist analyzing the influence of donor kidney quality on the immunologic outcome and applying the KDPI in a European cohort.Methods: This retrospective…2016 American Transplant Congress
Antibody Titers as Predictors of Kidney Graft Outcomes.
PURPOSE: Development of de novo donor specific antibody (dnDSA) following kidney transplantation is not uncommon. As laboratory techniques advance, rates of dnDSA have increased. However,…2016 American Transplant Congress
Assessment of mRNA Gene Profiles in Plasma Exosome to Predict Risk for Antibody-Mediated Rejection (ABMR) of Renal Allografts.
Background: ABMR is a major obstacle for successful transplant in HLA-sensitized (HS) patients. Complement-mediated and antibody-dependent cellular cytotoxicity (ADCC) are primarily mechanisms for ABMR. Previously…2016 American Transplant Congress
Kidney Transplantation with Strong Preformed Donor-Specific Antibodies: Impact of C1q-Binding Ability.
1Nephrology, CHP, Porto, Portugal; 2CSTP, Porto, Portugal.
HLA-incompatible kidney transplantation is associated with worse outcomes given the presence of donor-specific anti-HLA antibodies (DSA). Our aim was to investigate the association between preformed…2016 American Transplant Congress
Influence of Donor and Recipient CYP3A4, CYP3A5 and ABCB1 Genotypes on Outcomes in Liver Transplants.
Liver transplantation is a life-saving technique for patients with end-stage liver disease. Pharmacogenetics is promising to explain a part of variability of calcineurin inhibitors efficacy…2016 American Transplant Congress
Systematic Pathological Component Scores for Skin-Containing Vascularized Composite Allografts.
Successful application of skin-containing vascularized composite allografts (VCA) depends on accurate assessment of the graft status typically based on skin biopsies. A working classification (Banff…2016 American Transplant Congress
Protective Impact of the Kidney in SPK Transplants – Mechanisms for Improved Outcomes Compared with Solitary Transplants.
Surgery, University of Minnesota, Minneapolis, MN.
Purpose: Outcomes for SPK txps are superior to solitary pancreas txps. The basis for this difference is unknown. We sought to identify the biologic mechanism…2016 American Transplant Congress
Induction Therapy with Depleting Antibodies in Low Immunological Risk Renal Transplant Patients Treated with a Steroid Free Regimen – Comparison of Alemtuzumab vs. Antithymocyte Globulin.
Induction therapy with depleting antibodies reduces rejection rate and potentially improves efficacy of steroid free regimens after renal transplantation.This prospective, single-centre, cohort study evaluated cumulative…2016 American Transplant Congress
Mapping Heterogeneity in Antibody-Mediated Rejection Using Molecular Phenotypes and Archetype Analysis.
Archetype analysis is a method for identifying new relationships among samples without subdividing them into classes, finding a limited number of archetypical cases and calculating…
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