2016 American Transplant Congress
A Quantitative CD45 Assay May Improve Diagnostic Accuracy of the Diagnosis of Acute Cellular Rejection in Transplant Kidney Biopsies.
Purpose: We have previously shown that the total inflammatory load in transplant kidney biopsies (TxBx) can be determined with a high degree of accuracy using…2016 American Transplant Congress
How Tacrolimus Variability Affects Donor Specific Antibodies, Rejection and Outcome After Kidney Transplantation.
Purpose:To investigate the effect of tacrolimus(tac) variability on the development of Donor Specific Antibodies(DSA),rejection and outcome in relation to Age, Gender, Ethnicity and Body Mass…2016 American Transplant Congress
Randomized Controlled Trial of Mixed Acute Rejection Therapy in Renal Allografts: 3 Year Follow Up.
1U. of Cincinnati, Cincinnati; 2The Christ Hospital, Cincinnati.
Optimal therapy for mixed acute rejection (MAR) (defined as coexisting acute cellular and antibody mediated rejection) has not been defined. Rabbit antithymocyte globulin (rATG) has…2016 American Transplant Congress
The Coefficient of Variability of Tacrolimus Levels Can Predict Antibody-Mediated Rejection After Renal Transplantation.
Introduction. Antibody-mediated rejection (ABMR) is the major cause of allograft failure. We studied whether the coefficient of variability (CV) of blood levels of tacrolimus can…2016 American Transplant Congress
Donor Specif Antibody (DSA) Kinetics in Patients with Antibody Mediated Rejection (AMR) Treated with Plasmapheresis and Bortezomib.
Backgroud: The best choice to treat AMR is not supported by several evidences, and recently the interest in drugs as Bortezomib has improved. Aim: Evaluted…2016 American Transplant Congress
TNT009 and Its Parental Mouse Monoclonal Antibody TNT003 Target Complement Component C1s and Effectively Block Alloantibody-Induced Classical Complement Pathway Activation – The Preclinical Experience.
Introduction. Considering the key role of the classical complement pathway as a trigger of inflammation and injury in antibody-mediated rejection (ABMR), targeted classical pathway inhibition…2016 American Transplant Congress
Effect of Inflammation on Concentration of Intracellular Tacrolimus.
Background: The use of calcineurin inhibitors improved the outcome for transplant recipients. However, acute rejection (AR) and infection remained still an unsolved problem. We evaluated…2016 American Transplant Congress
Early Post-Transplant Patient, Graft Survival and Rejection Rates Under KAS.
Background: KAS, implemented on 12/4/14, resulted in changes in recipient, donor/recipient and tx characteristics that have the potential to affect post-tx outcomes.Data and Methods: We…2016 American Transplant Congress
Better Long-Term Renal Function with Lower Incidence of Acute Rejection and Lower CMV Infection in Renal Transplant Patients Treated with a Combination of Tacrolimus and Everolimus.
Surgery - Renal Transplant Unit, Università Cattolica del Sacro Cuore, Rome, Italy.
Introduction. Recent clinical trials have shown that the combination of CNIs with Everolimus (EVE) allows CNIs minimization, which may positively impact on chronic nephrotoxicity. Aim…2016 American Transplant Congress
Treatment of Hepatitis C Viral Infection with Novel Direct Acting Antivirals in Kidney Transplant Recipients – Single Center Experience.
Kidney transplant recipients (KTRs) with Hepatitis C virus infection (HCV+ve) have higher proteinuria and inferior patient and graft survival compared to HCV negative KTRs. Due…
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