2016 American Transplant Congress
Allograft TLR4 Receptor Signaling Induces Specific Early Inflammatory Events in Promotes Allografts Subjected to Prolonged Cold Ischemic Storage.
Dept. Immunology and Glickman Urological Institute, Cleveland Clinic, Cleveland, OH.
Engagement of Toll-like receptors (TLR) by endogenous danger-associated molecular pattern ligands contributes to the intensity of tissue inflammation, including the inflammation generated during ischemia-reperfusion injury…2016 American Transplant Congress
The Impact of Microvascular Inflammation (MVI) in Kidney Transplant Biopsies (KTxBx) Is Independent of Time Post-Transplant.
Detection of MVI in a KTxBx, often associated with antibody mediated rejection, is associated with a poor prognosis for kidney graft survival. However most information…2016 American Transplant Congress
Acute Rejection, New-Onset Diabetes After Transplant and Transplant Outcomes in Pediatric Kidney Recipients: Analysis of the Organ Procurement and Transplant Network/United Network for Organ Sharing (OPTN/UNOS) Database.
Nephrology, UCLA, Los Angeles, CA.
Introduction Our objective was to identify the associations of new-onset diabetes after transplant (NODAT) and acute rejection (AR) in predicting patient mortality and transplant failure…2016 American Transplant Congress
A New Diagnostic Score for Microvascular Inflammation in Antibody-Mediated Rejection in Heart Transplantation.
BackgroundThe ISHLT working formulation defines Intravascular Activated Mononuclear Cells (IAMC) as one of the histopathologic features of antibody-mediated rejection (ABMR) in heart transplantation. However, no…2016 American Transplant Congress
Conditional Deletion of mTOR in Myeloid Cells Inhibits Chronic Allograft Rejection – A Novel Role for Macrophages in Transplant Vasculopathy.
Most transplants eventually lost to chronic rejection under potent immunosuppression therapies where activation of innate immunity is suspected to play a major role in graft…2016 American Transplant Congress
Evaluation of a Risk-Stratified Induction Immunosuppression Protocol Utilizing Low-Dose Antithymocyte Globulin in Renal Transplantation.
Lower doses of rabbit-derived antithymocyte globulin (rATG) may result in less infection and cost, but may increase the incidence of acute rejection. We compared the…2016 American Transplant Congress
De Novo Anti-HLA DSA Characteristics and Subclinical Antibody Mediated Kidney Allograft Injuries.
Nagoya daini red cross hospital, Nagoya, Japan.
Background It has been reported that de novo donor-specific HLA antibody (dn DSA) production is associated with chronic antibody-mediated rejection (CAMR) which leads to poor…2016 American Transplant Congress
MicroRNAs in Urinary Sediments as Non-Invasive Tool to Detect Acute Rejection After Kidney Transplantation.
MicroRNAs in urine are suitable targets for non-invasive detection of acute rejection (AR), since they represent relatively stable analytes. Indeed, we found that PCR signals…2016 American Transplant Congress
Plasma Alemtuzumab Levels Show Great Interpatient Variability, but Are Not Associated with Late Acute Rejection in Simultaneous Pancreas-Kidney Recipients.
Introduction: Alemtuzumab induction followed by a steroid-free, tacrolimus (Tac) and mycophenolate mofetil (MMF) based regimen effectively prevented acute rejection after simultaneous pancreas-kidney transplantation (SPKT). Acute…2016 American Transplant Congress
Post-Transplant Reduction of Long Lived Plasma Cells from Peripheral Circulation Is Associated with Acute Rejection in Kidney Transplant Recipients.
Introduction:Plasma cells (PC) are usually defined functionally as antibody secreting cells (ASC). Depending upon their life span, they could either be short lived or long…
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