Articles tagged "Prophylaxis"

2021 American Transplant Congress
Outcomes in High Risk CMV Liver Transplants with Elevated MELD Scores
S. Freedman¹, K. Saunders², T. Sparkes¹, B. Masters¹, M. Plazak¹, K. Saharia³, D. Maluf³, B. Ravichandran²
¹University of Maryland Medical Center, Baltimore, MD, ²University of Maryland School of Pharmacy, Baltimore, MD, ³University of Maryland School of Medicine, Baltimore, MD
*Purpose: There is inconclusive evidence on the impact of MELD score on CMV viremia after liver transplantation. Following the implementation of Share 35, liver transplant…
2021 American Transplant Congress
An Evaluation of Pjp Prophylaxis and Anemia Among Renal Transplant Recipients
J. Hedvat, N. Poladi, D. Salerno, G. Dube, N. Lange
NewYork-Presbyterian Hospital, New York, NY
*Purpose: Dapone and atovaquone are therapeutic options for PJP prophylaxis in renal transplant recipients. The objective of this study was to evaluate the incidence of…
2021 American Transplant Congress
Breakthrough Cytomegalovirus DNAemia in High vs Intermediate Risk Heart Transplant Recipients
G. Huang¹, O. E. Beaird¹, M. Davis², M. Carlson¹, S. Chang¹, P. Gaynor¹, A. Fan², M. Deng³, A. Multani¹, A. Nsair³, J. Schaenman¹
¹Infectious Diseases, UCLA, Los Angeles, CA, ²Pharmacy, UCLA, Los Angeles, CA, ³Cardiology, UCLA, Los Angeles, CA
*Purpose: Cytomegalovirus (CMV) is one of the most common infections after transplantation and continues to cause significant morbidity and mortality despite prophylaxis and screening strategies.…
2021 American Transplant Congress
Probiotic Protocol to Reduce Perioperative Infection After Liver Transplantation
M. Jorgenson¹, Q. Yang², D. Yang², G. Leverson², C. Saddler², J. Smith², N. Safdar², L. Fernandez², D. Al-Adra²
¹UW Health, Madison, WI, ²UW School of Medicine and Public Health, Madison, WI
*Purpose: Evaluate efficacy and safety of a probiotic preparation to reduce perioperative infection in patients undergoing liver transplant surgery*Methods: Adult patients receiving liver transplantation from…
2021 American Transplant Congress
PDSA Model to Improve Pneumococcal Vaccine Adherence Among Kidney Transplant Candidates
J. M. Ramakrishna, L. Brumble, C. R. Libertin
Division of Infectious Diseases, Mayo Clinic, Florida, Jacksonville, FL
*Purpose: Streptococcus pneumoniae infections occur in solid organ transplant patients at a rate of 146 per 100,000 persons per year versus 11.5 per 100,000 persons…
2021 American Transplant Congress
Perioperative Anidulafungin Combined with Triazole Prophylaxis for the Prevention of Early Invasive Candidiasis in Lung Transplant Recipients
E. Sartain¹, K. Schoeppler¹, B. Crowther¹, J. B. Smith², M. Abidi³, T. J. Grazia⁴, M. Steele², T. Gleason², K. Porter², A. Gray²
¹University of Colorado Skaggs School of Pharmacy, Aurora, CO, ²Division of Pulmonary Sciences and Critical Care, University of Colorado, Denver, CO, ³Division of Infectious Disease, University of Colorado, Denver, CO, ⁴Baylor University Medical Center, Dallas, TX
*Purpose: Invasive candidiasis (IC) is a substantial cause of morbidity and mortality in lung transplant recipients (LTRs). Post-operative factors, such as prolonged hospital stay, central…
2021 American Transplant Congress
Methenamine for the Prevention of Recurrent UTIs Post-Renal Transplant
A. Bigness¹, S. Mohamed², S. Mandala¹, N. Khodieva², K. Robichaux³, H. Mohammed¹, J. Buggs⁴, A. Kumar¹, A. Brueckner⁵, L. Bowman⁵
¹Morsani College of Medicine, University of South Florida, Tampa, FL, ²College of Public Health, University of South Florida, Tampa, FL, ³Honors College, University of South Florida, Tampa, FL, ⁴Transplant Surgery, Tampa General Hospital, Tampa, FL, ⁵Department of Pharmacology, Tampa General Hospital, Tampa, FL
*Purpose: Urinary tract infections (UTIs) are a highly prevalent postoperative complication in kidney transplant recipients (KTRs), occurring in approximately 34% of patients. The common method…
2021 American Transplant Congress
Outcomes Among CMV Mismatched and Highly Sensitized Kidney Transplant Recipients Who Develop Leukopenia or Neutropenia
S. Brar¹, R. Berry², A. Raval³, Y. Tang³, F. Vincenti², N. Skartsis²
¹University of British Columbia, Vancouver, BC, Canada, ²University of California, San Francisco, San Francisco, CA, ³Merck and Co., Inc., Kenilworth, NJ
*Purpose: Kidney transplant recipients (KTRs) who receive antiproliferative agents for immunosuppression and valganciclovir for CMV prophylaxis are at high risk of developing leukopenia and neutropenia.…
2021 American Transplant Congress
Management of Drug Interactions During Protocolized Implementation of Posaconazole Immediately Post Heart Transplant
G. Waldman, C. Rogers Marks, J. Clark, A. Woo, L. Irwin, A. Gerlach, G. D. Lewis, J. A. Fishman
Massachusetts General Hospital, Boston, MA
*Purpose: Posaconazole (POSA) is a strong CYP3A4 inhibitor known to increase tacrolimus exposure by up to 4-fold. Initiation requires empiric tacrolimus dose adjustment and close…
2021 American Transplant Congress
Unquantified Blips Lead to CMV Slips – Post Transplant CMV Monitoring in High Risk Kidney Transplant Recipients
A. T. Payne¹, J. G. Timpone², A. Gilbert², B. Thomas², B. K. Lindner²
¹Georgetown University School of Medicine, Washington, DC, ²Medstar Georgetown University Hospital, Washington, DC
*Purpose: Cytomegalovirus (CMV) is a significant cause of morbidity, mortality, and graft failure after solid organ transplantation, with high risk (D+/R-) patients being the highest…