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American Transplant Congress abstracts

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Articles tagged "Prophylaxis"

  • 2022 American Transplant Congress

    Cmv-Specific Cell-Mediated Immune Reconstitution in High-Risk Hematopoietic Cell Transplant Recipients Receiving Letermovir Prophylaxis

    M. Z. Abidi1, K. Garth1, J. Gutman2, A. Weinberg1

    1Medicine, Infectious Disease, University of Colorado, Aurora, CO, 2Medicine, Hematology and Oncology, University of Colorado, Aurora, CO

    *Purpose: In the absence of antiviral prophylaxis following Hematopoietic Cell Transplant (HCT), the incidence of clinically significant cytomegalovirus reactivation (cCMV) is 30% in CMV seropositive…
  • 2022 American Transplant Congress

    Evaluation of Prophylactic Valganciclovir Dosing in Kidney Transplant Recipients at an Urban Transplant Institution

    E. Foster1, D. Pierce1, T. Cairns1, S. Borgetti2, I. Tzvetanov3, E. Benedetti3, C. Muran1

    1Pharmacy, University of Illinois at Chicago, Chicago, IL, 2Medicine, University of Illinois at Chicago, Chicago, IL, 3Surgery, University of Illinois at Chicago, Chicago, IL

    *Purpose: Dosing and duration of cytomegalovirus (CMV) prophylaxis with valganciclovir (VGC) in kidney transplant (KT) recipients is variable by transplant center. Prior studies have shown…
  • 2022 American Transplant Congress

    Incidence of Urinary Tract Infection or Asymptomatic Bacteriuria in Kidney Transplant Recipients with Sulfamethoxazole-Trimethoprim vs. Pentamidine for Pneumocystis Jiroveci Pneumonia Prophylaxis

    L. Selznick, H. Sweiss, C. Long, S. Bhayana, R. Hall

    University Health, San Antonio, TX

    *Purpose: To compare the incidence of urinary tract infection (UTI) or asymptomatic bacteriuria (ASB) post-kidney transplant (KT) with multiple Pneumocystis jiroveci pneumonia (PJP) prophylaxis regimens*Methods:…
  • 2022 American Transplant Congress

    Does a Second Transplant Increase the Risk for CMV Infection? An Evaluation of the Incidence of CMV Viremia in the Previously Transplanted Kidney Recipient

    J. Byrns1, G. Katz-Greenberg2

    1Pharmacy, Duke University Hospital, Durham, NC, 2Medicine, Duke University Medical Center, Durham, NC

    *Purpose: Cytomegalovirus (CMV) viremia is a common complication of kidney transplant recipients (KTR) with significant morbidity/mortality. Patients who receive multiple transplants are potentially at a…
  • 2022 American Transplant Congress

    Preemptive  Therapy for Cytomegalovirus (CMV) Disease Prevention in High-Risk CMV Donor Seropositive Recipient Seronegative (D+/R-) Liver Transplant Recipients in a Real-World Setting 

    K. M. Doss1, C. Kling1, M. R. Heldman1, N. Singh2, M. Wagener3, C. E. Fisher1, A. Limaye1

    1University of Washington, Seattle, WA, 2University of Pittsburgh, PIttsburgh, PA, 3University of Pittsburgh, Pittsburgh, PA

    *Purpose:  Preemptive therapy  (PET)  has  demonstrated superiority to antiviral prophylaxis  for  prevention of  cytomegalovirus (CMV)  disease  in  CMV  donor seropositive/recipient seronegative (D+R-)  liver transplant recipients …
  • 2022 American Transplant Congress

    Comparison of Cephalexin and Ciprofloxacin Prophylaxis for Urinary Tract Infection in Kidney Transplant Recipients

    N. A. Pauley, M. Fitzmaurice, A. Poparad-Stezar, B. Summers, A. Jantz

    Transplant Institute, Henry Ford Hospital, Detroit, MI

    *Purpose: Compare efficacy and safety outcomes of patients (pts) that received alternative agents as prophylaxis (ppx) for urinary tract infection (UTI) after kidney transplant (KT)…
  • 2022 American Transplant Congress

    Early versus Delayed Cytomegalovirus Prophylaxis in High-Risk Kidney Transplant Recipients

    A. Hutchins1, M. Leick2, M. Keck2, J. S. McMullen2

    1Pharmacy, Houston Methodist Hospital, Houston, TX, 2Pharmacy, Nebraska Medicine, Omaha, NE

    *Purpose: The purpose of this study is to determine the effect of delaying cytomegalovirus (CMV) prophylaxis to day of discharge or post-operative day (POD) 7…
  • 2021 American Transplant Congress

    Perioperative Anidulafungin Combined with Triazole Prophylaxis for the Prevention of Early Invasive Candidiasis in Lung Transplant Recipients

    E. Sartain1, K. Schoeppler1, B. Crowther1, J. B. Smith2, M. Abidi3, T. J. Grazia4, M. Steele2, T. Gleason2, K. Porter2, A. Gray2

    1University of Colorado Skaggs School of Pharmacy, Aurora, CO, 2Division of Pulmonary Sciences and Critical Care, University of Colorado, Denver, CO, 3Division of Infectious Disease, University of Colorado, Denver, CO, 4Baylor University Medical Center, Dallas, TX

    *Purpose: Invasive candidiasis (IC) is a substantial cause of morbidity and mortality in lung transplant recipients (LTRs). Post-operative factors, such as prolonged hospital stay, central…
  • 2021 American Transplant Congress

    Methenamine for the Prevention of Recurrent UTIs Post-Renal Transplant

    A. Bigness1, S. Mohamed2, S. Mandala1, N. Khodieva2, K. Robichaux3, H. Mohammed1, J. Buggs4, A. Kumar1, A. Brueckner5, L. Bowman5

    1Morsani College of Medicine, University of South Florida, Tampa, FL, 2College of Public Health, University of South Florida, Tampa, FL, 3Honors College, University of South Florida, Tampa, FL, 4Transplant Surgery, Tampa General Hospital, Tampa, FL, 5Department of Pharmacology, Tampa General Hospital, Tampa, FL

    *Purpose: Urinary tract infections (UTIs) are a highly prevalent postoperative complication in kidney transplant recipients (KTRs), occurring in approximately 34% of patients. The common method…
  • 2021 American Transplant Congress

    Outcomes Among CMV Mismatched and Highly Sensitized Kidney Transplant Recipients Who Develop Leukopenia or Neutropenia

    S. Brar1, R. Berry2, A. Raval3, Y. Tang3, F. Vincenti2, N. Skartsis2

    1University of British Columbia, Vancouver, BC, Canada, 2University of California, San Francisco, San Francisco, CA, 3Merck and Co., Inc., Kenilworth, NJ

    *Purpose: Kidney transplant recipients (KTRs) who receive antiproliferative agents for immunosuppression and valganciclovir for CMV prophylaxis are at high risk of developing leukopenia and neutropenia.…
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