ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Articles tagged "Primates"

  • 2019 American Transplant Congress

    Granulocyte – Colony Stimulating Factor (G-CSF) and Granulocyte – Macrophage Colony Stimulating Factor (GM-CSF) Administration Augments the Incidence of Peripheral Blood Suppressive Regulatory T Cells in Nonhuman Primates

    K. Sasaki, Y. Wang, L. Lu, J. Hughs, A. W. Thomson, M. B. Ezzelarab

    Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA

    *Purpose: Granulocyte-colony stimulating factor (G-CSF) and granulocyte-macrophage CSF (GM-CSF) are known to mobilize immune cells to the peripheral blood. We evaluated regulatory T cells (Treg)…
  • 2019 American Transplant Congress

    CD46 Transgene Modification and Thrombosis in Neonatal Porcine Islet Xenotransplantation

    M. Song, K. Samy, Q. Gao, R. P. Davis, F. Leopard, Z. Fitch, C. Bennett, G. R. Devi, B. H. Collins, A. D. Kirk

    Surgery, Duke University, Durham, NC

    *Purpose: Vascular thrombosis activation is an important cause for early xeno-islet loss. To better understand the thrombosis process in islet xenotransplantation and the effect of…
  • 2019 American Transplant Congress

    Anti- CD154 / CD40 Costimulation Blockade is Superior to Tacrolimus in Prolonging Survival in Pig-to-Nonhuman Primate Renal Xenotransplantation

    B. P. Lovasik1, A. J. Matar1, C. Breeden1, J. Jenkins2, J. Tector3, S. C. Kim1, A. B. Adams1

    1Emory Transplant Center, Emory University, Atlanta, GA, 2Yerkes National Primate Center, Emory University, Atlanta, GA, 3University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Costimulation blockade strategies targeting the CD40/CD154 pathway are highly effective in preventing xenograft rejection in pig-to-nonhuman primate (NHP) transplantation models. The aim of this…
  • 2019 American Transplant Congress

    Treg And Bone Marrow Infusion Promotes Survival Of Donor Kidney Grafted Months After Disappearance Of Mixed Chimerism

    K. Bruestle, P. Alonso-Guallart, E. Lopes, G. Pierre, N. Llore, H. Sakai, S. Kofman, D. Ekanayake-Alper, M. Sykes, A. Griesemer

    Columbia Center for Translational Immunology, Columbia University, New York City, NY

    *Purpose: Transient mixed chimerism induced with non-myeloablative conditioning in monkeys and humans induces tolerance to about 70% of donor kidney grafts transplanted at the time…
  • 2019 American Transplant Congress

    Complement Blockade in Kidney Recipients Prevents Delayed Graft Function and Antibody-Mediated Rejection in Non-Human Primates

    M. Eerhart1, J. Reyes1, C. Blanton1, J. Danobeitia1, P. Chlebeck1, L. Zitur1, J. Coonen1, S. Capuano1, A. D’Alessandro1, J. Torrealba2, W. Zhong1, Y. Yankol1, L. Fernandez1

    1University of Wisconsin, Madison, WI, 2UT Southwestern, Dallas, TX

    *Purpose: Ischemia-reperfusion injury (IRI) leading to inflammation, complement activation, cytokine release and acute kidney injury has been implicated in the mechanism for delayed graft function…
  • 2019 American Transplant Congress

    Phenotypic and Functional Analysis of Non-Activated and Allo-Activated Eomesodermin+ CD8+ T Cells in Humans and Nonhuman Primates

    A. Perez Gutierrez1, A. W. Thomson2, D. M. Metes2, M. B. Ezzelarab2

    1Transplantation Institute, University of Chicago Medicine, Chicago, IL, 2Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA

    *Purpose: The T-box transcription factors Eomesodermin (Eomes) and T-bet play a critical role in differentiation and function of CD8+ memory T cells (Tmem). We have…
  • 2019 American Transplant Congress

    Novel Insights into Blocking the IL-6 / IL-6 Receptor Pathway after Pig Kidney Xenotransplantation in Baboons

    H. Hara1, G. Zhang1, H. Iwase1, T. Yamamoto1, D. Ayares2, D. E. Eckhoff1, D. K. Cooper1

    1Surgery, University of Alabama at Birmingham, Birmingham, AL, 2Revivicor Inc., Blacksburg, VA

    *Purpose: IL-6 plays an important role in inflammation. The aims of the study were (i) to measure IL-6 in serum in baboons that received IL-6…
  • 2019 American Transplant Congress

    TMA Development in Kidney and Heart Xenografts Treated with Anti-CD40 or Anti-CD154 Antibodies

    D. H. Ma1, H. Sasaki1, J. M. O1, K. Ahrens1, D. Becerra1, C. G. Rickert1, D. M. Detelich1, T. Oura1, W. Somer1, I. Rosales2, R. N. Pierson1, J. Markmann1, J. C. Madsen1, T. Kawai1

    1Surgery, MGH, Boston, MA, 2Pathology, MGH, Boston, MA

    *Purpose: Genetically modified Galactose-α 1,3-galactose knockout transgenic swine expressing human CD55 (GTKO.hCD55) are resistant to hyperacute rejection of xenografts. We compare anti-CD154 and anti-CD40 antibody-based…
  • 2018 American Transplant Congress

    CD8-Expressing Transitional B Cells Dominate B Cell Reconstitution in Transplanted Monkeys Receiving Mixed Chimerism Conditioning

    K. Pruner, J. Paster, S. Wiebke, O. Jane, H. Isabel, D. Abbas, B. Gilles, M. Joren.

    Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA.

    IntroductionTolerance of heart or lung allografts have been achieved for the first time in nonhuman primates (NHPs) using a mixed chimerism conditioning regimen. However, the…
  • 2018 American Transplant Congress

    Humoral Immunity to CMV Remains Intact after Dual Targeting Desensitization in Allosensitized Nonhuman Primates

    P. Schroder, B. Ezekian, F. Saccoccio, J. Yoon, M. Dennis, K. Freischlag, J. Kwun, S. Permar, S. Knechtle.

    Department of Surgery, Duke University Medical Center, Durham, NC.

    Desensitization to remove donor specific antibody (DSA) is a way to expand the pool of potential donors for sensitized patients. This study compared the effects…
  • « Previous Page
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • …
  • 10
  • Next Page »

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences