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Articles tagged "Primary sclerosing cholangitis"

  • 2020 American Transplant Congress

    Single versus Dual Immunosuppression in Liver Transplantation for Autoimmune Liver Diseases

    S. Sterling1, S. Hamel1, C. Garza1, I. Feurer2, S. Rega2, S. Alexopoulos3, M. Izzy4

    1Pharmacy, Vanderbilt University Medical Center, Nashville, TN, 2Vanderbilt Transplant Center, Nashville, TN, 3Liver Transplant Surgery, Vanderbilt Transplant Center, Nashville, TN, 4Transplant Hepatology, Vanderbilt Transplant Center, Nashville, TN

    *Purpose: There is limited evidence on the optimal maintenance immunosuppression after liver transplant (LT) for primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), and autoimmune…
  • 2019 American Transplant Congress

    Clinical Outcomes of Living versus Deceased Donor Liver Transplantation for Primary Sclerosing Cholangitis: A Multicenter 15 Year Experience

    O. Y. Mousa1, K. D. Watt1, J. K. Heimbach2, A. P. Keaveny3, J. E. Eaton1, D. M. Harnois3, B. Taner3, E. J. Carey4, A. A. Moss4, C. B. Rosen5, T. Taner5

    1Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, 2Department of Surgery, Mayo Clinic, Rochester, MN, 3Department of Transplant, Mayo Clinic, Jacksonville, FL, 4Department of Transplant, Mayo Clinic, Scottsdale, AZ, 5Department of Transplant, Mayo Clinic, Rochester, MN

    *Purpose: MELD-based allocation is known to reduce access to deceased donor liver transplantation (DDLT) for patients with primary sclerosing cholangitis (PSC). Living donor liver transplantation(LDLT)…
  • 2018 American Transplant Congress

    DCD Utilization in Cholestatic Liver Disease: Distinct Outcomes between PSC and PBC Recipients

    J. Pasko, E. Maynard, E. Dewey, K. Roayaie, S. Orloff, D. Scott, W. Naugler, J. Ahn, C. Enestvedt.

    Abdominal Transplant Surgery, Oregon Health & Science University, Portland, OR.

    Background: Concern for inferior outcomes in patients with primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) have limited utilization of donation after cardiac death…
  • 2018 American Transplant Congress

    Rituximab Induction to Prevent the Recurrence of PSC after Liver Transplantation-The Lessons Learned from ABO-Incompatible Living Donor Liver Transplantation-

    Y. Yamada,1 K. Hoshino,1 M. Shinoda,1 H. Obara,1 S. Uemoto,3 T. Kaido,3 H. Okajima,3 T. Yagi,4 T. Yoshizumi,5 Y. Inomata,6 T. Hibi,6 K. Kubota,7 T. Suzuki,8 Y. Kitagawa,1 H. Egawa,2 T. Kuroda.1

    1Surgery, Keio University School of Medicine, Tokyo, Japan; 2Surgery, Institute of Gastroenterology, Tokyo Women's Medical University, Tokyo, Japan; 3Division of Hepato-Biliary-Pancreatic Surgery and Transplant Surgery, Kyoto University, Kyoto, Japan; 4Hepato-Biliary and Pancreatic Surgery, Okayama University, Okayama, Japan; 5Department of Surgery, Kyushu University, Fukuoka, Japan; 6Transplantation and Pediatric Surgery, Kumamoto University, Kumamoto, Japan; 7Department of Gastroenterological Surgery, Dokkyo Medical University, Tochigi, Japan; 8Department of Pediatric Surgery, Fujita Health University School of Medicine, Aichi, Japan.

    Background: Multiple studies have failed to reveal an effective method for preventing the recurrence of primary sclerosing cholangitis (PSC) after liver transplantation (LTx). A national…
  • 2017 American Transplant Congress

    Impact of Inflammatory Bowel Disease on Survival and Risk of Retransplantation of Primary Sclerosing Cholangitis Patients Following Liver Transplantation: UNOS Data Analysis.

    O. Mousa,1 N. Patel,1 J. Corral,1 D. Lee,2 J. Nguyen,2 K. Croome,2 D. Harnois.2

    1Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL; 2Transplant, Mayo Clinic, Jacksonville, FL

    Background: The impact of inflammatory bowel disease (IBD) on outcomes after liver transplantation (LT) for primary sclerosing cholangitis (PSC) has been inconclusive. Previous reports suggested…
  • 2017 American Transplant Congress

    Graft and Patient Survival in Liver Transplantation for Primary Sclerosing Cholangitis with Organs from DCD versus DBD Donors: Analysis of the UNOS Database.

    O. Mousa,1 J. Corral,1 M. Pang,1 D. Lee,2 J. Nguyen,2 K. Croome,2 D. Harnois.2

    1Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL; 2Transplant, Mayo Clinic, Jacksonville, FL

    Background: Primary sclerosing cholangitis (PSC) remains a major indication for liver transplantation (LT) worldwide. In an era of limited organ donation pool, assessment of PSC…
  • 2017 American Transplant Congress

    Course of Inflammatory Bowel Disease Activity in Primary Sclerosing Cholangitis Patients Undergoing Liver Transplantation.

    R. Parekh,1 M. Segovia,2 N. Kaur.1

    1Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI; 2Gastroenterology and Hepatology, Duke University Medical Center, Durham, NC

    Aim: Primary sclerosing cholangitis (PSC) is associated with inflammatory bowel disease (IBD). We aimed to review disease activity of IBD in patients with PSC undergoing…
  • 2017 American Transplant Congress

    Plasma Cell Hepatitis in Primary Sclerosing Cholangitis Patients: 15-Year Experience at a Transplant Center.

    J. Putra,1 T. Schiano,2 M. Fiel.3

    1Pathology, Icahn School of Medicine at Mount Sinai, New York, NY; 2Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY

    Background: Plasma cell hepatitis (PCH) is an uncommon liver graft dysfunction which occurs in liver transplant (LT) recipients of different etiologies other than autoimmune hepatitis.…
  • 2016 American Transplant Congress

    Tumor-Necrosis-Factor-α Antagonist Therapy for Inflammatory Bowel Disease After Liver Transplantation.

    R. Parekh, M. Segovia, N. Kaur.

    Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI.

    Background:The safety and effectiveness of tumor-necrosis-factor-α antagonist (anti-TNF-α) therapy for inflammatory bowel disease (IBD) has not been well-established in patients after liver transplantation (LT). We…
  • 2015 American Transplant Congress

    Early Recurrence of Primary Sclerosing Cholangitis After Liver Transplantation Has No Negative Impact on Patients outcome'

    B. Lowry,1 W. El Moghazy,1,2 G. Meeberg,1 N. Kneteman.1

    1Hepatobiliary Pancreatic Surgery and Transplantation, University of Alberta, Edmonton, AB, Canada; 2Surgery, Sohag University, Sohag, Egypt.

    Liver transplantation (LT) is the only therapeutic option for primary sclerosing cholangitis (PSC), however, recurrence of PSC (rPSC) post-LT occurs at rates ranging from 9-47%.…

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