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American Transplant Congress abstracts

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Articles tagged "Post-transplant malignancy"

  • 2020 American Transplant Congress

    Contrary to Expectation, the Use of Immune Checkpoint Inhibitors is Not Consistently Associated with Early Onset Allograft Rejection in Solid Organ Transplant Recipients

    I. Owoyemi1, C. M. Costello2, C. Thongprayoon1, S. Markovic3, H. Joerg4, C. C. Otley5, T. Taner6, A. R. Mangold2, N. Leung1, S. Herrmann1, A. Kukla1

    1Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, 2Department of Dermatology, Mayo Clinic, Scottsdale, AZ, 3Division of Medical Oncology, Mayo Clinic, Rochester, MN, 4Department of Cardiology, Mayo Clinic, Rochester, MN, 5Department of Dermatology, Mayo Clinic, Rochester, MN, 6Departments of Surgery & Immunology, Mayo Clinic, Rochester, MN

    *Purpose: Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy but are generally avoided in solid organ transplant recipients (SOTRs) due to concern for allograft rejection…
  • 2020 American Transplant Congress

    Tumor of Transplanted Kidney: Graft Resection Preserves Renal Function with Good Long-Term Oncologic Outcome

    J. Chlupac, T. Marada, M. Kudla, L. Janousek, J. Fronek

    Transplantation Surgery Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

    *Purpose: Incidence of urologic tumors is increased in renal transplant recipients. In case of a kidney transplant neoplasm, the graft-nephrectomy and hemodialysis reduce the quality…
  • 2020 American Transplant Congress

    De Novo Malignancy after Liver Transplantation for Alcoholic Cirrhosis: Incidence and Outcomes

    M. M. Pascale, E. Nure, G. Bianco, F. Frongillo, S. Agnes

    Transplant Unit, Fondazione "Policlinico A. Gemelli" UCSC - Rome, Roma, Italy

    *Purpose: De novo malignancy, frequent liver transplant (LT) complication, is one of the long-term major causes of mortality. Risk factors are related to immunosuppressive status,…
  • 2020 American Transplant Congress

    Short Tandem Repeat (STR) Analysis Identifies a Cancer Transmitted from an Organ Donor to 4 Transplant Recipients

    M. Park1, J. Van Ziffle1, E. Collisson1, J. Grenert1, S. Behr1, A. Gonzalez1, J. Chou1, S. Maisel1, T. Friedlander1, C. Freise1, J. Shoji1, T. Semrad2, P. Chin-Hong1, C. Atreya1

    1UCSF, San Francisco, CA, 2Gene Upshaw Memorial Tahoe Forest Cancer Center, Truckee, CA

    *Purpose: Organ donors are systematically screened for infection, while screening for malignancy is less rigorous. The true incidence of donor-transmitted malignancies is unknown due to…
  • 2020 American Transplant Congress

    Management of Pancreatic Cancer after Liver Transplantation: A 27-Year Single-Center Experience

    I. A. Ziogas, M. A. Rauf, L. K. Matsuoka, M. I. Montenovo, M. Izzy, S. P. Alexopoulos

    Vanderbilt University Medical Center, Nashville, TN

    *Purpose: The occurrence of de novo cancer after liver transplant (LT) is a leading cause of post-LT mortality and can be partially attributed to the…
  • 2020 American Transplant Congress

    MTOR-Inhibitor Regimens and Malignancy after Kidney Transplantation: Can the Risk Be Modified by Considering Human Leukocyte Antigen (HLA) Mismatch in Immunosuppression Selection?

    A. Santos1, C. Chen1, K. Alquadan2, M. A. Leghrouz2, X. Wen3

    1University of Florida, Gainesville, FL, 2Division of Nephrology, Hypertension, & Renal Transplantation, University of Florida, Gainesville, FL, 3Department of Pharmacy Practice, University of Rhode Island, Kingston, RI

    *Purpose: We investigated the outcomes of mammalian target of rapamycin inhibitor (MTORI) regimens in adult kidney transplant (KT) recipients (KTRs) in categories of donor/recipient pre-transplant…
  • 2020 American Transplant Congress

    Performance of the Retreat Score in Predicting Post-Transplant Hepatocellular Carcinoma Recurrence at a Large Academic Center

    N. Mahmud, N. Philips, S. Ekpanyapong, S. Prenner, M. Levine, R. Reddy, M. Hoteit

    Hospital of the University of Pennsylvania, Philadelphia, PA

    *Purpose: Post-transplant hepatocellular carcinoma recurrence (R-HCC) results in poor outcomes. The RETREAT score was recently derived to predict HCC recurrence, incorporating pre-transplant alpha fetoprotein and…
  • 2020 American Transplant Congress

    Transmission of Synovial Sarcoma by a Single Multiorgan Donor to Three Solid Organ Transplant Recipients

    J. Zhang, J. Lin, Y. Tian

    Beijing Friendship Hospital, Capital Medical University, Beijing, China

    *Purpose: To report 3 cases of donor-derived synovial sarcoma (SS) by a single multiorgan donor in China.*Methods: SS was diagnosed by the presence of SS18…
  • 2019 American Transplant Congress

    Lower Incidence of Posttransplant Malignancies under Vitamin D (Calcidiol) Treatment in Kidney Transplantation

    I. Revuelta1, V. Tubita2, J. Ugalde1, D. Cucchiari1, F. Oppenheimer1, F. Diekmann1, J. Campistol1, J. Torregrosa1

    1Department of Nephrology and Kidney Transplant, Hospital Clinic, Barcelona, Spain, 2Experimental Laboratory of Nephrology and Kidney Transplant, IDIBAPS, Barcelona, Spain

    *Purpose: An increasing body of evidence has emerged on the role of 1α,25-dihydroxyvitamin D3[1,25(OH) 2 D] in cell differentiation, which seems to have regulation properties…
  • 2019 American Transplant Congress

    Characterization Of Microscopic Hematuria Following Renal Transplant

    M. L. McDonald1, T. N. Duong2, N. Datta2, H. A. Gritsch1, S. Bunnapradist2

    1Department of Urology, Kidney and Pancreas Transplant Programs, UCLA, Los Angeles, CA, 2Division of Nephrology, Kidney and Pancreas Programs, UCLA, Los Angeles, CA

    *Purpose: The American Urological Association (AUA) recommends a CT Urography and cystoscopy for the evaluation of a single episode of microscopic hematuria (MH) in the…
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