2018 American Transplant Congress
Identification of Human SIRPa Diversity That Could Regulate Innate Allorecognition
Innate allorecognition is a process by which myeloid cells, such as monocytes, distinguish syngeneic from allogeneic cells. Monocytes that recognize donor cells as non-self differentiate…2018 American Transplant Congress
Glucocorticoid Receptor Polymorphism Affects Susceptibility of Dyslipidemia in Recipients One Year after Kidney Transplantation
Purpose. Dyslipidemia (DL) is a critical comorbidity after renal transplantation and can arise cardiovascular diseases. The relationship between developing of DL and glucocorticoid receptor (NR3C1)…2017 American Transplant Congress
Donor SIRPa Polymorphism Modulates the Innate Immune Response to Allogeneic Grafts.
Mice devoid of T, B, NK, and innate lymphoid cells distinguish between self and allogeneic non-self despite the absence of an adaptive immune system. When…2017 American Transplant Congress
Impact of Cytokine Gene Polymorphism on Clinical Outcome of Renal Transplantation.
Cytokine production is subject to genetic regulation, in such a way that gene polymorphisms at the level of promoter or coding regions can alter their…2017 American Transplant Congress
CMV Infection in Renal Transplant Recipients: Incidence and Efficacy of Prophylaxis According to Cytokine Single Nucleotide Polymorphisms.
Nephrology, Hospital Clínico San Carlos, Madrid, Spain
Objectives: To evaluate the influence of single nucleotide polymorphisms (SNP)of IL10, TNFα, IFNγand IL18 in the incidence of CMV infection in renal transplant recipients. Methods:…2017 American Transplant Congress
Noninvasive Renal Transplant Graft Monitoring in Single Institution Using Cell-Free DNA in Recipient Plasma via Insertion-Deletion Allele Polymorphism.
IntroductionThere is an unmet clinical need in renal transplantation towards early detection of donor organ damage. Serum creatinine(SCr) and biopsies are not ideal.Cell-free donor DNA(cfdDNA)…2017 American Transplant Congress
Benefits of Mycophenolate Sodium Over Mycophenolate Mofetil in Renal Transplant Patients Carrying UGT1A9 Polymorphism.
Nephrologist, Hospital Clínico San Carlos, Madrid, Spain
Aims: To analyze the differences in mycophenolic acid (MPA) pharmacokinetics and digestive side effects in renal transplant recipients on treatment with Mycophenolate mofetil (MMF) and…2017 American Transplant Congress
Impact of Polymorphisms of UGT 1 A9 on the Prognosis of Renal Transplant Patients. Association with Digestive Tumors.
Nephrologist, Hospital Clinico San Carlos, Madrid, Spain
The aim of this study was to evaluate the distribution of UGT1A9 promoter region T-275A and C-2152T single nucleotide polymorphisms (SNPs) in stable transplant patients…2016 American Transplant Congress
Differences in Tacrolimus Troughs and Doses Between Caucasians and African Americans with Two CYP3A5 Loss-of-Function Alleles: Looking Beyond CYP3A5 Expression.
Higher tacrolimus (TAC) dose requirements and lower TAC troughs (TT) in African Americans (AA) relative to Caucasians (CA) have been presumed to be due to…2015 American Transplant Congress
Single Nucleotide Polymorphisms (SNPs) Associated With Acute Rejection in European American Kidney Transplant Recipients: A Genome Wide Association Study (GWAS)
Purpose: Acute rejection (AR) is associated with increased risk of allograft loss. Therefore, we conducted a GWAS to determine SNPs associated with AR in a…
American Transplant Congress abstracts