2015 American Transplant Congress
Clinicopathological Scenarios (CPS) Defined by Viremia, Creatinine and Histology in Polyomavirus Nephropathy Differ in 1st and 2nd (Follow-Up) Biopsy
Pathology and Medicine, University of Maryland School of Medicine, Baltimore, MD.
Studies of sequential kidney biopsies (KB) after the diagnosis of polyomavirus allograft nephropathy (PVN) are scarce and clinicopathological evolution of PVN poorly understood. In practice…2015 American Transplant Congress
Plasmapheresis – A Previously Unrecognised Risk Factor for BK Viraemia
BK nephropathy is an important preventable cause of graft loss, with the only universally accepted risk factor being overall burden of immunosuppression. In the absence…2015 American Transplant Congress
Concerted T-Cell Activity Against Early and Late BKV-Antigens Is Necessary for Viral Clearance
Polyomavirus-BK (BKV) associated nephropathy is a known cause of graft failure. No specific therapy is established so far and viral load monitoring accompanied by adjustment…2015 American Transplant Congress
Impact of Sirolimus on the Risk of BK Viremia in Simultaneous Pancreas-Kidney Transplant Recipients
BackgroundBK virus (BKV) is a common infection in simultaneous pancreas-kidney (SPK) transplant recipients. Data in kidney transplant recipients suggest that immunosuppression regimens containing an mTORi…2015 American Transplant Congress
Alemtuzumab Induction Is Associated With Higher Risk of Polyomavirrus Associated Nephropathy (PVAN) in Kidney Transplant Recipients
1Transplant, Mayo Clinic, Jacksonville, FL; 2Pharmacy, Mayo Clinic, Jacksonville, FL.
Incidence of PVAN on protocol kidney biopsies with alemtuzumab induction is unknown.Methods:The 1-year risk of PVAN was retrospectively compared between 200 consecutive primary kidney recipients…2015 American Transplant Congress
A Single Center Comparison of Various BK Viremia Elimination Protocols
Division of Transplantation, University Of Southern California. Keck Med Center, Los Angeles, CA.
Aim BK infection remains a significant complication post kidney transplantation. Best practices in BK management have evolved over time. The purpose of the study was…2015 American Transplant Congress
Donor and Recipient Pretransplant Polyoma BK Serostatus: Relationship to BK-Viremia After Renal Transplantation
Surgery, Albany Medical College, Albany, NY.
Background:Polyoma virus BK nephropathy is a serious complication after renal transplantation and is associated with a significant risk of graft loss and dysfunction. This study…2015 American Transplant Congress
Evaluation of the Use of Leflunomide for the Prevention of BK Nephropathy in Renal Transplant Recipients- A Single Center Experience
Rush University Medical Center, Chicago, IL.
Objective: The purpose of this study was to compare the efficacy of leflunomide in combination with reduced immunosuppression versus reduction of immunosuppression alone for the…2015 American Transplant Congress
Is BK Viral Subtype Distribution of Donor And/Or Recipient Important for Subsequent BK Viral Infection After Living-Donor Transplantation?
Background: Source and risk factors for developing BK virus (BKV) infection after renal transplantation are unresolved. By genotyping of urine and blood, we looked for…2015 American Transplant Congress
Evaluation of Leflunomide for the Treatment of BK Viremia and Biopsy Proven BK Nephropathy: A Single Center Experience
Purpose:The objective was to evaluate the use of leflunomide in BK viremia (BKV) and biopsy proven BK nephropathy (BKN) in kidney and kidney-pancreas transplant recipients.Methods:We…
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