2015 American Transplant Congress
Donor and Recipient Pretransplant Polyoma BK Serostatus: Relationship to BK-Viremia After Renal Transplantation
Surgery, Albany Medical College, Albany, NY.
Background:Polyoma virus BK nephropathy is a serious complication after renal transplantation and is associated with a significant risk of graft loss and dysfunction. This study…2015 American Transplant Congress
Evaluation of the Use of Leflunomide for the Prevention of BK Nephropathy in Renal Transplant Recipients- A Single Center Experience
Rush University Medical Center, Chicago, IL.
Objective: The purpose of this study was to compare the efficacy of leflunomide in combination with reduced immunosuppression versus reduction of immunosuppression alone for the…2015 American Transplant Congress
Is BK Viral Subtype Distribution of Donor And/Or Recipient Important for Subsequent BK Viral Infection After Living-Donor Transplantation?
Background: Source and risk factors for developing BK virus (BKV) infection after renal transplantation are unresolved. By genotyping of urine and blood, we looked for…2015 American Transplant Congress
Evaluation of Leflunomide for the Treatment of BK Viremia and Biopsy Proven BK Nephropathy: A Single Center Experience
Purpose:The objective was to evaluate the use of leflunomide in BK viremia (BKV) and biopsy proven BK nephropathy (BKN) in kidney and kidney-pancreas transplant recipients.Methods:We…2015 American Transplant Congress
Impact of Donor and Recipient BKV Serostatus and the Effect of Ciprofloxacin Prophylaxis on BK Viremia Risk After Kidney Transplant
Background: BK virus (BKV) is a common infection in kidney transplant recipients. Due to widespread latent BKV infection in the general population, it is possible…2015 American Transplant Congress
Switching from Tacrolimus to Low-Dose Cyclosporine A Preserves Allograft Function in Presumptive and Definitive Polyomavirus-Associated Nephropathy
Switching from tacrolimus(Tac) to low-dose cyclosporine A(CsA) is recommended for preventing BK virus-associated nephropathy(BKVAN) and preserving allograft function in BKVAN patients, but systematic evaluations were…2015 American Transplant Congress
T Cell Receptor Repertoire Analysis of BKV-Specific T Cells in Peripheral Blood Samples By Next Generation Sequencing Reveals Differential Role and Kinetics of CD4 and CD8 T Cell Clones in Viral Control
Background:BKV-specific T cells play the crucial role in controlling virus reactivation and analyses of their frequencies have been previously performed in different studies. However, nothing…2015 American Transplant Congress
A Prospective Pilot Study Evaluating the Safety and Efficacy of Everolimus for the Prevention of CMV and BK Viral Infection (BKV) in Broadly Sensitized Kidney Transplant Recipients Following Desensitization With IVIG and Rituximab: Interim Analysis
Introduction: Everolimus, a second generation mTOR inhibitor, may prevent CMV and BKV infection after kidney transplantation. Broadly sensitized patients are at greater risk of viral…2015 American Transplant Congress
Everolimus Conversion to Treat BK Virus Infection in Kidney Transplant Recipients
IntroductionmTORi's reduce BKV large T antigen expression in vitro and are associated with lower rates of BKV infection in clinical studies.MethodsPilot single center, randomized, open-label…2015 American Transplant Congress
Role of CMV, BKV, and Immunosupression Non-Adherence in Early and Late De Novo Donor Specific Anti-HLA Antibody Development and Outcomes
This analysis aims to identify appropriate de novo DSA (dnDSA) screening points and delineate the post-transplant (txp) scenarios preceding dnDSA development to aid in clinical…
American Transplant Congress abstracts