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Articles tagged "Pancreas"

  • 2022 American Transplant Congress

    Generation Of Insulin Producing Cells From Pancreatic Tissue With Long Standing Type 1 Diabetes

    Y. Garciafigueroa, J. B. Pollett, N. L. Thai, R. Bottino

    Imagine Pharma, Pittsburgh, PA

    *Purpose: AIPCs (Activated Islet Proliferating Cells), are a novel cell population from isolated human islets obtained using a simple culture protocol that can generate cells…
  • 2022 American Transplant Congress

    Donor-Derived Duodenal Adenocarcinoma of a Bladder-Drained Pancreas Allograft

    D. Isaacson1, J. Steggerda1, Y. Xue1, G. B. Auffenberg2, N. N. Katariya3

    1Northwestern University, Chicago, IL, 2Urology of St. Louis, St. Louis, MO, 3Mayo Clinic, Phoenix, AZ

    *Purpose: Donor-derived malignancies are rare but frequently present with aggressive pathology and high mortality rates [PMID 32627325]. The urologic literature demonstrates an increased risk of…
  • 2022 American Transplant Congress

    Decellularized Human Pancreatic Extracellular Matrix-Based Physiomimetic Microenvironment for Human Islet Culture

    A. Asthana1, D. Chaimov1, R. Tamburrini2, S. J. Walker3, G. Orlando1

    1Wake Forest Baptist Medical Center, Winston-Salem, NC, 2University of Wisconsin Hospital and Clinics, Madison, WI, 3Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC

    *Purpose: Maintenance of human islet viability and function ex vivo can be a significant bottleneck for both regenerative medicine as well as tissue engineering applications.…
  • 2022 American Transplant Congress

    Characterization of Activated Islet Proliferating Cells (AIPCs) During Maturation to Pseudo-Islets

    Y. Garciafigueroa, J. B. Pollett, N. Thai, R. Bottino

    Imagine Pharma, Pittsburgh, PA

    *Purpose: We have previously described a novel population of cells developed from human islets called AIPCs (Activated Islet Proliferating Cells). AIPCs co-express CD133, glucagon and…
  • 2022 American Transplant Congress

    Bionic Pancreas – 3D Bioprinting of a Bionic Organ with a Vascular System – Results of Transplantation in Large Animals

    M. Wszola1, M. Klak2, A. Berman3, M. Kolodziejska1, T. Bryniarski1, G. Tymicki1, T. Dobrzanski1, D. Szkopek4, K. Roszkowicz-Ostrowska5, J. Wolinski5, A. Dobrzyn6, A. Kaminski7

    1Foundation of Research and Science Development, Warsaw, Poland, 2Foundation for Research and Science Development, Warsaw, Poland, 3Polbionica Ltd., Warsaw, Poland, 4Institute of Animal Physiology and Nutrition Jan Kielanowski of the Polish Academy of Sciences,, Jabłonna, Poland, 5Institute of Animal Physiology and Nutrition Jan Kielanowski of the Polish Academy of Sciences, Jablonna, Poland, 6Laboratory of Cell Signaling and Metabolic Disorders, Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland, 7Department of Transplantology and Central Tissue Bank, Medical University of Warsaw, Warsaw, Poland

    *Purpose: There is lack organs for transplantation. The transplantation of the pancreas is recommended in diabetes with complications. The combination of cell biology and 3D-bioprinting…
  • 2022 American Transplant Congress

    Infections Requiring Hospitalization After Simultaneous Pancreas-Kidney Transplantation Compared to Kidney Transplantation Alone

    J. Grasberger1, F. Ortiz2, A. Ekstrand2, V. Sallinen1, M. Lempinen1, I. Helanterä1

    1Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland, 2Nephrology, Helsinki University Hospital, Helsinki, Finland

    *Purpose: Although infections related to surgical complications are more common after simultaneous pancreas-kidney transplantation (SPK) compared to kidney transplantation alone (KTA), the burden of infections…
  • 2022 American Transplant Congress

    Bionic Pancreas – The First Results of Functionality of 3D-Bioprinted Bionic Tissue Model Transplantation with Pancreatic Islets

    M. Klak1, M. Wszola1, A. Berman1, A. Filip1, A. Kosowska2, J. Olkowska-Truchanowicz2, G. Tymicki1, M. Rachalewski1, T. Bryniarski1, M. Kolodziejska1, T. Dobrzanski3, D. Ujazdowska1, J. Wejman4, I. Uhrynowska-Tyszkiewicz2, A. Kaminski2

    1Foundation of Research and Science Development, Warsaw, Poland, 2Medical University of Warsaw, Warsaw, Poland, 3Polbionica Ltd., Warsaw, Poland, 4Center for Pathomorphological Diagnostics Ltd, Warsaw, Poland

    *Purpose: Tissue engineering is currently on advanced stage of development which gives a possibilities for novel strategy of personal treatment of type 1 diabetes. AIM:…
  • 2022 American Transplant Congress

    Bioink Based on the DECM for 3D-Bioprinting of Bionic Pancreas – First Results of Animal

    M. Klak1, K. Kosowska1, T. Bryniarski1, I. Lojszczyk1, T. Dobrzanski2, G. Tymicki1, A. Filip1, A. A. Szczepankiewicz3, R. Olkowski4, A. Kosowska4, A. Berman1, A. Kaminski4, M. Wszola1

    1Foundation of Research and Science Development, Warsaw, Poland, 2Polbionica LTD, Warsaw, Poland, 3Institute of Experimental Biology M. Nencki PAN, Warsaw, Poland, 4Medical University of Warsaw, Warsaw, Poland

    *Purpose: Tissue engineering is an interdisciplinary field involving activities based on two interrelated areas: developing new methods to repair, regenerate and replace damaged tissues and…
  • 2022 American Transplant Congress

    Towards Bionic Organs: Biocompatibility Of Newly Developed Porcine Decm-based Hydrogels.

    M. Rachalewski, M. Klak, D. Ujazdowska, P. Cywoniuk, T. Dobrzanski, G. Tymicki, K. Kosowska, T. Bryniarski, A. Berman, M. Wszola

    Foundation of Research and Science Development, Warsaw, Poland

    *Purpose: There is a growing interest in fabrication of bioinks which on one hand biocompatible and on the other hand possess mechanical properties which would…
  • 2022 American Transplant Congress

    Prevalence and Clinical Significance of Pancreatic Cystic Lesions in Immunosuppressed Patients with Solid Organ Transplantation

    Y. Yu, H. Jo, Y. Choi, J. Lee, D. Kim

    HBP surgery and liver transplantation, Korea University College of Medicine and School of Medicine, Seoul, Korea, Republic of

    *Purpose: Solid organ transplant recipients have an increased risk of cancer due to immunosuppressive therapy. Pancreatic cystic lesions (PCLs) are increasingly being detected, some with…
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