2020 American Transplant Congress
AIPCs Home to and Engraft in the Pancreas When Injected Intravenously
1Imagine Pharma, Pittsburgh, PA, 2Allegheny Health Network, Pittsburgh, PA
*Purpose: AIPCs (Activated Islet Proliferating Cells) are a recently developed cell population generated from isolated islets of mice and humans. AIPCs are over 65% CD133-,…2020 American Transplant Congress
Implications for Facilitated Pancreas Transplant Allocation with the Removal of Donor Service Area
*Purpose: Facilitated Pancreas (FP) Allocation, modified in August 2016 to be metric-based rather than opt-in, defines an eligible center as one that has transplanted at…2020 American Transplant Congress
Impact of Sarcopenia on Simultaneous Pancreas and Kidney Transplantation Outcomes: A Retrospective Observational Cohort Study
Transplant Surgery, University of California San Francisco, San Francisco, CA
*Purpose: Sarcopenia has been identified as a recognized predictive variable for surgical outcomes. We hypothesized that sarcopenia could be a key measure to identify frail…2020 American Transplant Congress
Lower Extremity Vascular Complications after Simultaneous Pancreas Kidney Transplant
University of California, San Francisco, San Francisco, CA
*Purpose: Type 1 diabetes mellitus (DM) is the leading indication for simultaneous pancreas kidney transplantation (SPK). Prior work has demonstrated a 2% incidence of lower…2020 American Transplant Congress
Early Tacrolimus-LCP Conversion Due to Adverse Effects in Pancreas Transplant Recipients Improves Tolerance But Not Graft Survival
*Purpose: Tacrolimus-LCP (LCPT) is an extended release formulation of tacrolimus which has been shown to have fewer adverse drug effects (ADE) than immediate release tacrolimus…2020 American Transplant Congress
Outcomes of Simultaneous Pancreas-Kidney vs. Kidney Alone Transplants in Type 2 Diabetic Recipients: A Multivariate Analysis of U.S. Transplants
*Purpose: The impact of simultaneous pancreas-kidney (SPK) transplants in uremic, non-obese, insulin-treated type 2 diabetic (T2DM) recipients is not well described. We analyzed the SRTR…2020 American Transplant Congress
Management of Pancreatic Cancer after Liver Transplantation: A 27-Year Single-Center Experience
Vanderbilt University Medical Center, Nashville, TN
*Purpose: The occurrence of de novo cancer after liver transplant (LT) is a leading cause of post-LT mortality and can be partially attributed to the…2020 American Transplant Congress
Pancreatic Mesenchymal Stromal Cells (MSC) Contain a Subset of Islet Progenitor Cells Capable of Regenerating Islets and Reversing Diabetes
*Purpose: To identity islet precursor cells residing in pancreatic MSC culture preparations that contribute to islet regeneration and restoration of islet cell function in both…2020 American Transplant Congress
Construction of Three-Dimensional Vascularized Functional Beta-Cells Tissues Using a Layer-by-Layer Cell Coating Technique
*Purpose: Regenerative therapy for type I Diabetes Mellitus has been expected to be a promising treatment. A subcutaneous site is an ideal candidate for stem…2020 American Transplant Congress
High Laminin Alpha 5 Expression is Observed in the Pancreas of Chronic Pancreatitis Patients and Correlates with Poor Autologous Islet Transplant Outcome
Baylor University Medical Ctr, Dallas, TX
*Purpose: During chronic pancreatitis (CP), the extracellular matrix (ECM) of the pancreas is destroyed by a vicious cycle of parenchymal autodigestion by digestive exocrine enzymes…
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