Articles tagged "non-heart-beating"

2016 American Transplant Congress
Normothermic Perfusion of Livers Donated After Circulatory Death: A New Clinically Relevant Experimental Model.
Y. Cao,¹ H. Chew,^1,2 K. Fernandez,¹ L. Gao,¹ J. Villanueva,¹ M. Hicks,¹ P. Macdonald,^1,2 K. Dhital,^1,2 H. Pleass.³
¹Victor Chang Cardiac Research Institute, Sydney, NSW, Australia; ²Cardiac Transplant Unit, St. Vincent's Hospital, Sydney, NSW, Australia; ³The Department of Surgery, Westmead Hospital, Sydney, NSW, Australia.
Aim. Transplantation using livers donation after circulatory death (DCD) is associated with worse outcomes compared to using donation after brain death (DBD). Considerable research resources…
2016 American Transplant Congress
Rapid Withdrawal of Donation After Cardiac Death Donors.
K. Mekeel,¹ J. Trageser,² W. Garrison,² J. Berumen,¹ L. Stocks,² A. Hemming.¹
¹Surgery, University of California-San Diego, La Jolla, CA; ²Lifesharing, San Diego, CA.
Purpose: Potential organ donors may be lost if procurement needs to occur emergently due to hemodynamic instability or family request, in particular if serologies and…
2016 American Transplant Congress
Hydrogen Sulfide Supplementation Helps Mitigate Effects of Ischemia Reperfusion Injury in a Murine Model of Donation After Cardiac Death Renal Transplantation.
J. Grewal,¹ I. Lobb,¹ M. Saha,² J. Jiang,² A. Haig,¹ A. Sener.^1,2
¹Microbiology & Immunology, University of Western Ontario, London, Canada; ²Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, Canada.
Donation after cardiac death(DCD) renal grafts experience a combination of prolonged warm and cold ischemia leading to greater ischemia reperfusion injury(IRI) that results in higher…
2016 American Transplant Congress
Deceased Organ Donors with Zero Organs Transplanted: Why and How Can We Improve?
P. Lange,¹ S. Rudich,¹ N. Obaseki,¹ J. Punch.²
¹Medical Division, Gift of Life Michigan, Ann Arbor, MI; ²Surgery, University of Michigan, Ann Arbor, MI.
Organ recovery professionals and donor hospitals are under intense pressure to go to whatever lengths necessary to provide transplantable organs. However, such a mentality can…
2016 American Transplant Congress
Hypothermic Machine Perfusion Ameliorates Vasospasm and Edema of Podocytes and Renal Tubular Epithelial Cells Through Upregulating Expression of Krüppel-Like Factors 2.
Z. Zhong,¹ D. Ko,² Y. Wang,¹ Q. Ye.¹
¹Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Wuhan, Hubei, China; ²Massachusetts General Hospital, Department of Urology, Harvard Medical School, Boston, MA.
Protective mechanisms of hypothermic machine perfusion (MP) remain largely unknown. Vascular branches of the renal arteries of 6 kidneys in 320 donors were unexpectedly injured…
2016 American Transplant Congress
Does Location Matter for Withdrawal of Donation After Cardiac Death Donors ?
K. Mekeel,¹ W. Garrison,² J. Trageser,² J. Berumen,¹ L. Stocks,² A. Hemming.¹
¹Surgery, University of California-San Diego, La Jolla, CA; ²Lifesharing, San Diego, CA.
Purpose: Withdrawal for DCD donors traditionally occurs in the OR. Families often refuse to proceed with DCD donation if they are unable to be present…
2016 American Transplant Congress
Controlled Cardiac Death Donor Program for Kidney Transplantation – Spanish Multicenter Experience with Two Years of Follow-Up.
J. Portoles,¹ M. Perez-Saez,² D. Hernandez-Marrero,² O. Lafuente,¹ F. Diekmann,² N. Maruri Kareaga,² M. Rodriguez-Ferrero,² F. Llamas,² M. Mazuecos,² J. Juega,² E. Melilli,² A. Rodriguez-Benot,² A. Alonso,² J. Pascual.²
¹Nephrology, U.H.Puerta de Hierro-RedinRen, Majadahonda, Spain; ²Nephrology, SENTRA-GEODAS Group, Madrid, Spain.
Background: Controlled donation after cardiac death (cDCD) programs are running in several countries for years. National transplant organization (ONT) has developed a nation-wide program in…
2016 American Transplant Congress
Donor AKI Does Not Adversely Affect the Outcome Following DCD Kidney Transplant.
I. Qaqish, D. Haakinson, K. Reddy, M. Smith, H. Khamash, R. Heilman.
Mayo Clinic, Phoenix, AZ.
BackgroundTransplanting kidneys from donation after cardiac death (DCD) donors has been associated with good outcome, but the impact of added donor AKI on the outcome…
2016 American Transplant Congress
Association Between Delayed Graft Function and Long-Term Outcomes After Kidney Transplantation from Donors After Circulatory Death.
P. Clayton,^1,2,3 G. Russ,^1,2,3 S. McDonald,^1,2,3 S. Chadban.^1,4,5
¹Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry, Royal Adelaide Hospital, Adelaide, SA, Australia; ²Central Northern Adelaide Renal and Transplantation Service, Royal Adelaide Hospital, Adelaide, SA, Australia; ³School of Medicine, University of Adelaide, Adelaide, SA, Australia; ⁴Renal Medicine, Royal Prince Alfred Hospital, Sydney, NSW, Australia; ⁵Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
Purpose: Delayed graft function (DGF) is associated with worse long-term outcomes after kidney transplantation from donation after brain death (DBD) donors. We aimed to determine…
2016 American Transplant Congress
Kidney Donor Profile Index and Recipient BMI Are Potent Predictors of Six Month Deceased Donor eGFR as Opposed to EPTS.
A. Agarwal, W. Ally, D. Maluf, S. Pelletier, K. Brayman.
University of Virginia Health System, Charlottesville, VA.
Background: Kidney Donor Profile Index (KDPI) has been shown to be predictive of both short and long term graft survival and is used by transplant…

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