Articles tagged "Nephropathy"

2021 American Transplant Congress
Oxalate Nephropathy After Kidney Transplant: Defining Histological Patterns, Contributing Factors and Graft Outcome
N. Jakob¹, A. Chuu¹, J. Ninan¹, E. Lim¹, N. Zhang¹, H. Amer², F. Cosio², H. Wadei³, M. Ryan¹, C. Cortese³, L. Cornell², M. Keddis¹
¹Nephrology, Mayo Clinic, Scottsdale, AZ, ²Nephrology, Mayo Clinic, Rochester, MN, ³Nephrology, Mayo Clinic, Jacksonville, FL
*Purpose: The objective of this study is to evaluate KTx recipients with biopsy proven oxalate nephropathy (ON) to better define risk factors, histologic patterns and…
2021 American Transplant Congress
Effect of Defibrotide on Kidney Ischemia Reperfusion Injury in a Preclinical Renal Transplant Model
P. Pine¹, Z. Sun², A. Matas³, J. Shi¹, A. Ebrahimnejad¹, M. Zanette⁴, P. Halloran⁵, J. S. Bromberg⁶, R. Hanvesakul⁷
¹Jazz Pharmaceuticals, Palo Alto, CA, ²Johns Hopkins Medicine, Baltimore, MD, ³Univ of Minnesota, Minneapolis, MN, ⁴Jazz Pharmaceuticals, Philadelphia, PA, ⁵Univ of Alberta, Edmonton, AB, Canada, ⁶Univ of Maryland School of Medicine, Baltimore, MD, ⁷Jazz Pharmaceuticals, Oxford, United Kingdom
*Purpose: Ischemia reperfusion injury (IRI) is a major contributor to graft failure. During organ removal and preservation, ischemia results in anaerobic respiration and cellular damage.…
2020 American Transplant Congress
BK-Viral Nephropathy after Transplantation of a Non-Renal Organ
A. Schwarz¹, C. Bara², J. Braesen³, J. Gottlieb⁴
¹Nephrology Department, Hannover Medical School, Hannover, Germany, ²Cardiothoracic Surgery Department, Hannover Medical School, Hannover, Germany, ³Pathology Department, Hannover Medical School, Hannover, Germany, ⁴Pulmonary Department, Hannover Medical School, Hannover, Germany
*Purpose: Patients with non-renal organ transplantation may suffer BK-viral nephropathy (BKVN) of their orthotopic kidneys by reactivation of their own viral population living in latency…
2020 American Transplant Congress
The Importance of Caveolin-1 Immunohistochemical Staining for BK Nephropathy Seen after Kidney Transplantation
E. Arpali¹, E. Sunnetcioglu², Y. Özlük², A. Turkmen³, F. S. Oğuz¹
¹Medical Biology, Istanbul University School of Medicine, Istanbul, Turkey, ²Pathology, Istanbul University School of Medicine, Istanbul, Turkey, ³Nephrology, Istanbul University School of Medicine, Istanbul, Turkey
*Purpose: To understand the importance of molecular expression of Caveolin-1 in BKV nephropathy seen after kidney transplantion.*Methods: The kidney transplant patients who had a graft…
2020 American Transplant Congress
Long-Term Outcome of Kidney Transplantation for IgA Nephropathy: A Single-Center Experiences
M. Tasaki¹, K. Saito¹, Y. Nakagawa², N. Imai³, Y. Ito³, K. Takahashi⁴, Y. Tomita¹
¹Division of Urology, Department of Regenerative & Transplant, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan, ²Division of Urology, Juntendo University, Tokyo, Japan, ³Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan, ⁴Otsukadai Clinic, Tokyo, Japan
*Purpose: Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis worldwide, with a high recurrence rate after kidney transplantation (KTx). The aim of this…
2020 American Transplant Congress
Clinical Study of Standard versus Reduced Dose Tacrolimus Combined with Generic Mycophenolate Mofetil in De Novo Kidney Transplantation
J. Bang, C. Oh
Department of Surgery, Ajou University Medical School, Suwon, Korea, Republic of
*Purpose: The lowering of calcineurin inhibitor exposure is possibly considered as the proper strategy to prevent calcineurin inhibitor induced nephrotoxicity in kidney transplant. This clinical…
2020 American Transplant Congress
Impact of Depleting Induction Agents on BK Virus and Polyomavirus Associated Nephropathy
J. Clark¹, A. Barlow¹, A. Haririan²
¹University of Maryland Medical Center, Baltimore, MD, ²University of Maryland School of Medicine, Baltimore, MD
*Purpose: Polyomavirus associated nephropathy (PVAN) is an opportunistic infection associated with graft loss and rejection. Due to limited treatment options, identifying kidney transplant recipients at…
2020 American Transplant Congress
IgA Nephropathy Outcomes after Kidney Transplantation in an Early Corticosteroid Withdrawal Center
S. Kurian¹, S. Spierling², B. Barrick¹, J. Rice¹, J. Case¹, C. Marsh¹
¹Scripps Center for Organ and Cell Transplantation, La Jolla, CA, ²Scripps Whittier Diabetes Institute, La Jolla, CA
*Purpose: IgA nephropathy (IgAN) is the most frequent biopsy-proven primary glomerular disease. Recurrent IgA after transplantation often leads to allograft loss. A lower risk of…
2020 American Transplant Congress
A Long-Term Follow-Up Study of High-Dose Intravenous Cyclosporine Combined Plasma Exchange in the Treatment of FSGS Recurrence after Renal Transplantation – A Single Center Clinical Experience
Y. Cui, M. F. Wang, C. C. Wei, J. Y. Wu
Kidney Disease Center, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
*Purpose: There was still lack of effective treatment for focal segmental glomerulosclerosis(FSGS)recurrence after renal transplantation. The purpose of this study was to explore the risk…
2019 American Transplant Congress
Recurrent Diabetic Nephropathy Despite Intensive Glycemic Control: An Observational Cohort Study
M. Coemans, E. Van Loon, E. Lerut, D. Kuypers, B. Sprangers, P. Gillard, C. Mathieu, G. Verbeke, M. Naesens
KU Leuven, Leuven, Belgium
*Purpose: After kidney transplantation, recurrence of diabetic nephropathy has been reported. The presentation and kinetics of recurrent diabetic nephropathy and its risk factors remain however…