Articles tagged "Nephropathy"

2016 American Transplant Congress
Potential Biomarkers and Treatment for BK Virus Associated Nephropathy.
M. Borkar,¹ V. Srivastava,² R. Cunnington,¹ T. Sharma,¹ L. Tibbles.¹
¹Faculty of Mediicne, University of Calgary, Calgary, AB, Canada; ²CSIR-Indian Institute of Toxicology Research, Lucknow, Uttar Pradesh, India.
Background: BK polyomavirus assoiciated nephropathy (BKVAN) is one of the major complications in renal transplants, and is associated with significant fibrosis It is important to…
2016 American Transplant Congress
Comparison of Efficacy of Different Regimens for Treating Recurrent IgA Nephropathy After Kidney Transplantation.
G. Chen, C. Wang, L. Chen, J. Qiu, C. Wang, J. Fei, S. Deng, J. Li, G. Huang, Q. Fu.
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Background Recurrent IgA nephropathy is a common complication after kidney transplantation. How to treat recipients with recurrent IgA nephropathy is still controversial. There are two…
2016 American Transplant Congress
Evaluation of Polyomavirus (BK) Treatment and Clinical Outcomes in Pediatric Kidney Transplant Recipients: A >10 Year Single Center Retrospective Experience.
R. Liverman,¹ E. Kraus,¹ R. Garro,² B. Warshaw,² P. Winterberg,² R. George.²
¹Children's Healthcare of Atlanta, Atlanta, GA; ²Division of Pediatric Nephrology, Emory University School of Medicine, Atlanta, GA.
BK viremia (BKV) is a serious infectious complication after kidney transplantation and can lead to BK nephropathy (BKN) and allograft loss. We reviewed our experience…
2016 American Transplant Congress
Urinary CXCL9 Protein as Biomarker for BK Polyoma Viremia.
N. Sarabu,¹ R. El-Rifai,² J. Augustine,¹ A. Padiyar,¹ A. Huml,¹ T. Young,¹ V. Rodriguez,¹ D. Hricik.¹
¹Division of Nephrology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH; ²Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL.
Introduction: BK infection is common in kidney transplant patients and can result in accelerated loss of allografts. Management involves empiric lowering of immunosuppression, which can…
2016 American Transplant Congress
Slipping Through the Cracks: Late Onset BK Viremia.
J. Gandhi,¹ M. Mackenzie,¹ D. DeWolfe,² F. Cardarelli,³ M. Pavlakis,³ C. Tan.^1,4
¹Center for Virology & Vaccine Research, Beth Israel Deaconess Medical Center (BIDMC), Boston, MA; ²Division of Nephrology, BIDMC, Boston, MA; ³The Transplant Institute, BIDMC, Boston, MA; ⁴Division of Infectious Disease, BIDMC, Boston, MA.
Introduction: Most studies indicate that viremia caused by BK virus (BKV), the step preceding BKV associated nephropathy (BKVN) in kidney transplant recipients (KTRs), occurs within…
2016 American Transplant Congress
Novel Nuclear Factor-κB Activation Inhibitor, Dehydroxymethylepoxyquinomicin, Prevents the Development of Chronic Cyclosporine Nephropathy in Rats.
S. Morita,¹ K. Shinoda,¹ S. Tamaki,¹ H. Kono,² Y. Kanno,³ K. Umezawa,⁴ K. Nakagawa,² M. Oya.¹
¹Urology, Keio University School of Medicine, Tokyo, Japan; ²Urology, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Chiba, Japan; ³Nephrology, Tokyo Medical University, Tokyo, Japan; ⁴Molecular Target Medicine Screening, Aichi Medical University, Nagakute, Aichi, Japan.
Purpose:The nephrotoxicity of the calcineurin inhibitors including cyclosporine is a major problem in the kidney transplantation. We investigated the effect of a novel nuclear factor-κB…
2016 American Transplant Congress
HCK Is a Potential Mediator of Renal Fibrosis.
C. Wei,¹ M. Menon,¹ L. Li,² Z. Yi,¹ K. Keung,³ C. Woytovich,¹ I. Greene,¹ W. Zhang,¹ J. He,¹ B. Murphy.¹
¹Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY; ²Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY; ³Centre for Transplant and Renal Research, Westmead Millenium Institute, University of Sydney at Westmead Hospital, New South Wales, Australia.
Background: Renal fibrosis is the consequence of excessive accumulation of extracellular matrix that occurs in patients with chronic kidney disease (CKD) and in kidney transplant…
2016 American Transplant Congress
Kidney Transplantation from Thin Basement Membrane Nephropathy Donor.
C. Choi,¹ A. Han,¹ S.-Y. Kim,¹ S. Cho,¹ M.-J. Cho,¹ C. Lee,¹ S. Ahn,¹ S.-K. Min,¹ J. Ha,¹ M. Park,² S. Kim,³ I. Jung,¹ S.-I. Min.¹
¹Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea; ²Laboratory Medicine, Korea Organ Donation Agency, Seoul, Republic of Korea; ³Surgery, Myongji Hospital, Goyang, Gyeonggi-do, Republic of Korea.
PurposeThin basement membrane nephropathy (TBMN) is the most common cause of persistent glomerular hematuria. Most individuals with TBMN shows benign course, but it is hard…
2016 American Transplant Congress
Analysis of FSGS (Focal Segmental Glomerulosclerosis) Recurrence After Renal Transplantation.
J. Mansur, G. Basso, M. Cristelli, G. Mata, T. Sandes-Freitas, G. Kirsztajn, H. Tedesco-Silva, J. Medina-Pestana.
Nephrology-Division, Hospital do Rim - UNIFESP, São Paulo, Brazil.
Purpose: To describe clinical-laboratorial profile and outcome of patients diagnosed with recurrent FSGS submitted to plasmapheresis.Methods: Retrospective single-center cohort study including all patients with recurrent…
2015 American Transplant Congress
The Role of Quantitative Assay of Urinary Decoy Cells as a Screening and Follow-Up Tool in Renal Transplant Recipients With Polyomavirus BK Infection
G. Huang, J. Qiu, C.-X. Wang, J.-G. Fei, S.-X. Deng, J. Li, G.-D. Chen, Q. Fu, R.-H. Deng, L.-Z. Chen.
Department of Organ Transplantation, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Polyomavirus BK nephropathy (BKVN) is an important infectious complication in kidney transplant patients. Urinary cytology is effective for early diagnosis of BKVN. However, quantitative assay…