Articles tagged "Methodology"

2022 American Transplant Congress
An Updated Estimate of Post-Transplant Survival After Implementation of the New Donor Heart Allocation Policy
K. A. Lazenby¹, N. Narang², K. M. Pelzer³, G. Ran¹, W. F. Parker³
¹Pritzker School of Medicine, University of Chicago, Chicago, IL, ²Advocate Heart Institute, Advocate Christ Medical Center, Chicago, IL, ³Department of Medicine, University of Chicago, Chicago, IL
*Purpose: Published estimates showing lower post-transplant survival after implementation of the new heart allocation policy may be biased downward due to incomplete follow-up on surviving…
2022 American Transplant Congress
Reality Capture Using Light Detection and Ranging 3D Photography of Liver Grafts for Volumetric Assessment: A Proof-of-Concept Preliminary Study
K. E. Karakasi¹, G. Katsanos², I. Karolos³, V. Tsioukas³, G. Tsoulfas⁴
¹University Transplantation Surgical Clinic, Heppocrateion General Hospital, Thessaloniki, Greece, ²Transplantation, Aristitle University of Thessaloniki, Thessaloniki, Greece, ³School of Runal and Surveying Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece, ⁴University Transplantation Surgical Clinic, Hippocrateion’ General Hospital of Thessaloniki, Thessaloniki, Greece
*Purpose: Reality capture uses various technical means to capture a digital 3D model representation of a subject from the real world. Whole liver graft volume…
2022 American Transplant Congress
Influence of the Competing Risk of Recipient Death on the Risk Estimation of Kidney Transplant Failure
M. Coemans¹, G. Verbeke², B. Döhler³, C. Süsal³, M. Naesens¹
¹Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ²Leuven Biostatistics and Statistical Bioinformatics Centre, Leuven, Belgium, ³Heidelberg University Hospital, Heidelberg, Germany
*Purpose: Prognostic models for kidney transplant failure are often based on methods that censor for recipient death. Death is a competing event biasing the risk…
2021 American Transplant Congress
A Noninvasive Diagnostic Approach for Molecular Monitoring of Face Transplant Recipients
C. Snopkowski¹, P. Rabbani², H. Yang¹, Z. Berman², G. Diep², C. Li¹, T. Muthukumar¹, R. Ding¹, D. Ceradini², M. Suthanthiran¹
¹Weill Cornell Medical Institute, Department of Medicine, Division of Nephrology, NY, NY, ²NYU Langone Health, Hansjörg Wyss Department of Plastic Surgery, NY, NY
*Purpose: Skin biopsies are currently the gold standard for evaluating the inflammatory status of face allografts. However, “tape stripping” is emerging as a noninvasive technique…
2021 American Transplant Congress
The Clinical Validation of a Dried Blood Spot Method for Simultaneous Tacrolimus and Creatinine Measurement
M. I. Francke¹, S. Bouarfa², B. van Domburg², D. van de Velde², M. E. Hellemons³, O. C. Manintveld⁴, S. M. Last-Koopmans⁵, M. B. Mulder², D. A. Hesselink¹, B. C. de Winter²
¹Internal medicine, nephrology and transplantation, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ²Hospital Pharmacy, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ³Pulmonary medicine, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ⁴Cardiology, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ⁵Hematology, Erasmus MC, University Medical Center, Rotterdam, Netherlands
*Purpose: Monitoring tacrolimus concentrations and kidney function after transplantation is important to avoid tacrolimus under- and overexposure and its clinical consequences, including acute nephrotoxicity. Using…
2021 American Transplant Congress
Poor Reliability of Karnofsky Performance Score in Kidney Transplant Candidates
M. R. Stedman, D. J. Watford, G. M. Chertow, J. C. Tan
Medicine, Stanford University, Palo Alto, CA
*Purpose: The Karnofsky Performance Status (KPS) Scale has been used as a proxy for frailty and as a predictor of transplant outcomes, however reliability of…
2021 American Transplant Congress
Needs of People with Kidney Transplantation During the Covid 19 Pandemic and Its Confinement, and the Role of Communication Technologies Through the “Patient Experience”
I. Revuelta¹, E. Palou², R. Scandurra³, F. Oppenheimer¹, F. Diekmann¹, J. Escarrabill², B. Bayés¹
¹Department of Nephrology and Kidney Transplant, Hospital Clinic, Barcelona, Spain, ²Chronic care program and patient experience, Hospital Clinic, Barcelona, Spain, ³Department of Statistics, Universidad Autónoma de Barcelona, Barcelona, Spain
*Purpose: During the COVID-19 pandemic, healthcare services have focused on the care of acute processes and there is a risk of not meeting the needs…
2020 American Transplant Congress
Microarray and RNA-Seq Analysis of Rejection in Formalin-Fixed Paraffin-Embedded (FFPE) Biopsies: Comparing FFPE to Conventionally Stabilized (RNAlater Solution) Biopsies
P. Halloran¹, K. Famulski¹, J. Reeve¹, J. Huang², N. Alexandrov²
¹University of Alberta, Edmonton, AB, Canada, ²R&D Transplant Diagnostics Division, Thermo Fisher Scientific, Los Angeles, CA
*Purpose: Molecular understanding of organ transplant biopsies requires genome-wide measurements and molecular classifiers. To assess potential of performing molecular diagnostics on formalin-fixed paraffin-embedded (FFPE) biopsies,…
2020 American Transplant Congress
The State of Interventional Clinical Trials in Solid Organ Transplant: Insights from a Systematic Analysis of Clinicaltrials.gov
A. C. Swaminathan¹, J. Li¹, K. Chiswell¹, W. McManigle¹, I. O’Doherty², W. Fitzsimmons³, J. L. Todd¹, S. Tibbs⁴, S. M. Palmer¹
¹Duke Clinical Research Institute, Durham, NC, ²Critical Path Institute, Tuscan, AZ, ³Fitzsimmons LLC, Chicago, IL, ⁴Duke University, Durham, NC
*Purpose: The approach to immunosuppression after solid organ transplant has remained relatively unchanged for almost 20 years, despite the high prevalence of immunosuppression-related complications and…
2020 American Transplant Congress
Challenges in Examining Transplant Outcomes in Patients with Fontan-Associated Liver Disease
R. T. Fischer¹, M. H. Kim², A. Nguyen³, S. R. Kumar³, J. Bucuvalas⁴, E. F. Glynn¹, M. A. Hoffman¹, J. Emamaullee³
¹Children's Mercy Hospital, Kansas City, MO, ²Children's Hospital-Los Angeles, Los Angeles, CA, ³University of Southern California, Los Angeles, CA, ⁴Mount Sinai Kravis Children's Hospital, New York, NY
*Purpose: The Fontan procedure has allowed patients born with single ventricle physiology to survive into adulthood. It is projected that the mean age of Fontan…

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