Articles tagged "Metabolic disease"

2020 American Transplant Congress
Domino Transplantation – Expanding the Liver Donor Pool to the Pediatric Recipient
U. Ekong¹, N. Yazigi¹, K. Khan¹, S. Kaufman¹, K. Chapman², E. Leon², N. Ah Mew², A. Kroemer¹, R. Girlanda¹, J. Hawksworth¹, C. Matsumoto¹, T. Fishbein¹
¹MedStar Georgetown Transplant Institute, Washington, DC, ²Genetics, Children's National Hospital, Washington, DC
*Purpose: Background: Maple syrup urine disease (MSUD) is an inherited autosomal recessive metabolic disorder of amino acid metabolism, caused by a defect of the branched-chain…
2020 American Transplant Congress
Sleeve Gastrectomy Compared with Gastric Bypass for Morbidly Obese Liver Transplant Candidates: A Decision Analysis
R. A. Choudhury¹, D. Yoeli¹, G. Hoeltzel², H. B. Moore¹, H. Yaffe¹, K. R. Dumon³, N. N. Williams³, P. L. Abt⁴, K. D. Conzen¹, J. J. Pomposelli¹, E. A. Pomfret¹, T. L. Nydam¹
¹Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ²Thomas Jefferson University Hospital, Philadelphia, PA, ³Department of Surgery, University of Pennsylvania Hospital, Philadelphia, PA, ⁴Department of Surgery- Division of Transplantation Surgery, University of Pennsylvania Hospital, Philadelphia, PA
*Purpose: The use of bariatric surgery has increased for morbidly obese liver transplant candidates for whom placement on the waitlist is often restricted until they…
2020 American Transplant Congress
Long Term Outcome of Patients Transplanted for Non Alcoholic Steatohepatitis Related Cirrhosis
W. Alhamoudi¹, I. Salih², S. Yousif², M. Shawkat³, K. Bzeizi², S. Alghamdi², A. Albenmousa², D. Broering²
¹Medicine, King Saud University, Riyadh, Saudi Arabia, ²Liver Transplant, King Faisal Specialist Hospital, Riyadh, Saudi Arabia, ³Internal Medicine, Minia University, Minia, Egypt
*Purpose: Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver disease worldwide. Cirrhosis secondary to Nonalcoholic Steatohepatitis (NASH) is projected to…
2020 American Transplant Congress
Progression of Insulin Resistance after Liver Transplantation – Prospective Study
I. Mikova¹, D. Erhartova¹, K. Dvorakova¹, P. Sedivy², M. Drobny², M. Dezortova², M. Hajek², M. Cahová³, H. Dankova³, E. Sticova⁴, V. Lanska⁵, P. Trunecka¹
¹Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ²Radiodiagnostic and Interventional Radiology Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ³Experimental Medicine Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ⁴Department of Clinical and Transplant Pathology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ⁵Medical Statistics Unit, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
*Purpose: Insulin resistance (IR) plays an important role in pathogenesis of nonalcoholic fatty liver disease (NAFLD) and other diseases. The data about prevalence and evolution…
2020 American Transplant Congress
A NASHional Crisis: Liver Transplantation Outcomes in Female Hispanics
R. A. Sosa¹, A. Q. Terry¹, M. Rossetti¹, F. M. Kaldas², B. V. Naini¹, J. Nevarez-Mejia¹, V. M. Groysberg¹, S. Younan², R. W. Busuttil², D. W. Gjertson¹, J. W. Kupiec-Weglinski², E. F. Reed¹
¹Pathology and Lab Medicine, UCLA, Los Angeles, CA, ²Surgery, UCLA, Los Angeles, CA
*Purpose: Obesity and metabolic syndrome have recently become an epidemic with Hispanics bearing a disproportionate burden. Non-alcoholic steatohepatitis (NASH) is a severe immune-mediated stage of…
2019 American Transplant Congress
The Comparison of Glycemic Profiles during Post-Operative Early Period between Liver and Kidney Transplantation Assessed by Continuous Glucose Monitoring System
H. Yu¹, H. Jin², S. Lee², J. Yang¹, S. Park², S. Ahn¹, H. Hwang¹
¹Surgery, Chonbuk National University Medical School and Hospital, Jeonju, Korea, Republic of, ²Internal Medicine, Chonbuk National University Medical School and Hospital, Jeonju, Korea, Republic of
*Purpose: Newly developed hyperglycemia and worsening of previously well controlled glucose control are common after transplantation because of stressful condition and immunosuppressive agents including of…
2019 American Transplant Congress
Metabolic Liver Transplantation – Can We Afford It?
N. Yazigi¹, W. Fujiwara²
¹Transplant Institute, MedStar Georgetown University Hospital, Washigton, DC, ²Georgetown University Medical School, Washigton, DC
*Purpose: Despite major improvement in medical and nutritional care of pediatric patients suffering from intoxication inherited metabolic disorders, their long term outcomes remain guarded. Liver…
2019 American Transplant Congress
Living Donor vs. Deceased Donor Liver Transplantation for Pediatric Patients with Metabolic Liver Disease
G. Gu, Q. Xia
Renji Hospital, Shanghai, China
*Purpose: Liver transplantation has been accepted as the appropriate treatment option for pediatric metabolic liver disease and the most common methods used are LDLT and…
2019 American Transplant Congress
Metabolic Liver Transplant: A Single Cooperative 2002-2017
N. Yazigi¹, K. Chapman²
¹Transplantation, MedStar Georgetown University Hospital, Washigton, DC, ²Transplantation, Children's National Rare Disease Institute, Washington, DC
*Purpose: Liver transplant (LT) can increase quality and quantity of life for patients with inherited metabolic diseases (IMDs) who suffer severe and unpredictable complications despite…
2019 American Transplant Congress
Pediatric Liver Transplantation for Metabolic Disorders without Intrinsic Liver Disease: A 25 Year Experience
P. Vuong, L. Lee, N. Mineyev, S. Conlon, R. Shetty, W. Concepcion, C. A. Bonham, A. Gallo, T. Pham, S. Busque, M. L. Melcher, G. M. Enns, C. O. Esquivel
Stanford University Medical Center, Palo Alto, CA
*Purpose: Liver transplantation (LT) for acute and chronic end-stage-liver-disease is a well-accepted therapy in pediatrics. However, for children with metabolic disorders (MD) without intrinsic liver…