Articles tagged "Metabolic disease"

2020 American Transplant Congress
Impact of Dialysis and Diabetes on Survival in Recipients of Combined Heart-Kidney Transplant
J. Parekh¹, H. Chau², G. Schnickel², J. Berumen², K. Mekeel²
¹University of California, San Diego, La Jolla, CA, ²Surgery, University of California, San Diego, La Jolla, CA
*Purpose: Mounting data shows a survival benefit of combined heart-kidney transplantation in patients with heart and renal failure. However, little has been done to understand…
2020 American Transplant Congress
Intravenous Administration of Mitochondria Minimizes Liver Ischemia Reperfusion Injury in Lean and Diet Induced Obese Mice
T. Rousselle¹, E. Patterson¹, C. Kuscu¹, J. Pierre², C. Kuscu¹, J. Eason¹, D. Maluf¹, V. Mas¹, A. Bajwa¹
¹Dept of Surgery, Transplant Research Institute, James D. Eason Transplant Institute, University of Tennessee Health Science Center, Memphis, TN, ²Dept of Pediatrics, UTHSC, Memphis, TN
*Purpose: Ischemia induces altered bioenergetics within cells with increased mitochondrial swelling and reactive oxygen species and that ultimately degrade of cellular function. Ischemia reperfusion injury…
2020 American Transplant Congress
Long-Term Metabolic Control and Health Outcomes in Maple Syrup Urine Disease Following Liver Transplantation in Children and Young Adults
C. Ewing¹, K. Soltys², K. Strauss³, G. Mazariegos², R. Sindhi², J. Vockley², P. McKiernan², R. Squires², G. Bond², A. Khanna², J. Squires²
¹School of Medicine, University of Pittsburgh, Pittsburgh, PA, ²Children's Hospital of Pittsburgh, Pittsburgh, PA, ³Clinic for Special Children, Strausburg, PA
*Purpose: Determine outcomes and branch-chain amino acid (BCAA - leucine [LEU], isoleucine [ISO], and valine [VAL]) levels at 1-3, 4-7, and 8-10 years for patient’s…
2020 American Transplant Congress
Domino Transplantation – Expanding the Liver Donor Pool to the Pediatric Recipient
U. Ekong¹, N. Yazigi¹, K. Khan¹, S. Kaufman¹, K. Chapman², E. Leon², N. Ah Mew², A. Kroemer¹, R. Girlanda¹, J. Hawksworth¹, C. Matsumoto¹, T. Fishbein¹
¹MedStar Georgetown Transplant Institute, Washington, DC, ²Genetics, Children's National Hospital, Washington, DC
*Purpose: Background: Maple syrup urine disease (MSUD) is an inherited autosomal recessive metabolic disorder of amino acid metabolism, caused by a defect of the branched-chain…
2020 American Transplant Congress
Sleeve Gastrectomy Compared with Gastric Bypass for Morbidly Obese Liver Transplant Candidates: A Decision Analysis
R. A. Choudhury¹, D. Yoeli¹, G. Hoeltzel², H. B. Moore¹, H. Yaffe¹, K. R. Dumon³, N. N. Williams³, P. L. Abt⁴, K. D. Conzen¹, J. J. Pomposelli¹, E. A. Pomfret¹, T. L. Nydam¹
¹Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ²Thomas Jefferson University Hospital, Philadelphia, PA, ³Department of Surgery, University of Pennsylvania Hospital, Philadelphia, PA, ⁴Department of Surgery- Division of Transplantation Surgery, University of Pennsylvania Hospital, Philadelphia, PA
*Purpose: The use of bariatric surgery has increased for morbidly obese liver transplant candidates for whom placement on the waitlist is often restricted until they…
2020 American Transplant Congress
Long Term Outcome of Patients Transplanted for Non Alcoholic Steatohepatitis Related Cirrhosis
W. Alhamoudi¹, I. Salih², S. Yousif², M. Shawkat³, K. Bzeizi², S. Alghamdi², A. Albenmousa², D. Broering²
¹Medicine, King Saud University, Riyadh, Saudi Arabia, ²Liver Transplant, King Faisal Specialist Hospital, Riyadh, Saudi Arabia, ³Internal Medicine, Minia University, Minia, Egypt
*Purpose: Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver disease worldwide. Cirrhosis secondary to Nonalcoholic Steatohepatitis (NASH) is projected to…
2020 American Transplant Congress
Progression of Insulin Resistance after Liver Transplantation – Prospective Study
I. Mikova¹, D. Erhartova¹, K. Dvorakova¹, P. Sedivy², M. Drobny², M. Dezortova², M. Hajek², M. Cahová³, H. Dankova³, E. Sticova⁴, V. Lanska⁵, P. Trunecka¹
¹Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ²Radiodiagnostic and Interventional Radiology Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ³Experimental Medicine Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ⁴Department of Clinical and Transplant Pathology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ⁵Medical Statistics Unit, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
*Purpose: Insulin resistance (IR) plays an important role in pathogenesis of nonalcoholic fatty liver disease (NAFLD) and other diseases. The data about prevalence and evolution…
2020 American Transplant Congress
A NASHional Crisis: Liver Transplantation Outcomes in Female Hispanics
R. A. Sosa¹, A. Q. Terry¹, M. Rossetti¹, F. M. Kaldas², B. V. Naini¹, J. Nevarez-Mejia¹, V. M. Groysberg¹, S. Younan², R. W. Busuttil², D. W. Gjertson¹, J. W. Kupiec-Weglinski², E. F. Reed¹
¹Pathology and Lab Medicine, UCLA, Los Angeles, CA, ²Surgery, UCLA, Los Angeles, CA
*Purpose: Obesity and metabolic syndrome have recently become an epidemic with Hispanics bearing a disproportionate burden. Non-alcoholic steatohepatitis (NASH) is a severe immune-mediated stage of…
2020 American Transplant Congress
The Long Term Impact of Metabolic Syndrome on Post-Donation in Living Kidney Donors
C. Chen, T. Yu, Y. Chuang, S. Tsai, M. Wu
Division of Nephrology, Taichung Veterans General Hospital, Taichung, Taiwan
*Purpose: The long waiting list for kidney transplant (KTx) in Taiwan, the willingness of transplant centers increase to accept complex donors, eg. metabolic syndrome (MS).…
2020 American Transplant Congress
The Impact of Preoperative Glucose Intolerance and Hypertension on the Living Kidney Donors
T. Hiramitsu¹, T. Tomosugi¹, K. Futamura¹, M. Okada¹, N. Goto¹, S. Narumi¹, K. Uchida², Y. Watarai¹
¹Department of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya Aichi, Japan, ²Department of Transplant Surgery, Masuko Memorial Hospital, Nagoya Aichi, Japan
*Purpose: Recently the mortality of living kidney donors was demonstrated to be significantly worse than that of healthy general population. However, the impact of preoperative…

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