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Articles tagged "Metabolic complications"

  • 2017 American Transplant Congress

    Effect of Everolimus-Based Immunosuppressive Regimen on New Onset of Diabetes After Kidney Transplantation – A 24 Month Subanalysis from the ELEVATE Study.

    H. Holdaas,1 S. Chadban,1 J. de Fijter,1 L. Rostaing,1 U. Mancilla,1 P. Lopez,2 G. Bader,2 J. Cruzado,1 M. van der Giet.1

    1ELEVATE Study Group, Oslo, Norway; 2Novartis Pharma AG, Basel, Switzerland

    Purpose: New onset diabetes after transplantation (NODAT) is a common metabolic complication which affects long-term patient survival and graft outcomes. Most of the immunosuppressive drugs…
  • 2017 American Transplant Congress

    Kidney Transplant Recipient Intermediate and Long Term Outcomes for Living Donor Gifted Lithiasis.

    S. Doshi, M. Yaqub, T. Taber, M. Mujtaba, D. Mishler, O. Adebiyi, C. Sundaram, J. Powelson, A. Sharfuddin.

    Indiana University Health, Indianapolis

    BACKGROUND: Nephrolithiasis is considered at least a relative contraindication to living donor nephrectomy due to the potential for adverse outcomes of recurrence, obstruction and infection.…
  • 2017 American Transplant Congress

    Obesity Predicts New-Onset Diabetes After Live Kidney Donation.

    K. Lentine,1 A. Naik,2 N. Lam,3 M. Schnitzler,1,6 H. Xiao,1 D. Axelrod,4 G. Hess,5 B. Kasiske,6 A. Garg,7 S. Gustafson,6 D. Brennan,8 D. Segev.9,6

    1St. Louis Univ, St. Louis; 2U Michigan, Ann Arbor; 3U Alberta, Edmonton, Canada; 4E Carolina Univ, Greenville; 5Symphony Health, Philadelphia; 6Scientific Registry of Transplant Recipients, Minneapolis; 7Western Univ, London, Canada; 8Washington Univ, St. Louis; 9Johns Hopkins, Baltimore

    End-stage renal disease is uncommon in living kidney donors (LKD), but recent data suggest that most kidney failure developing late after donation is due to…
  • 2017 American Transplant Congress

    Bariatric Operations at a Service of the Transplant Surgery.

    A. Keidar,1 R. Yemini,1 M. Ben David,1 E. Nesher,2 J. Vinkler,3 M. Broun,2 E. Mor.2

    1Surgery, Beilinson Hospital, Tel Aviv, Israel; 2Transplantation, Beilinson Hospital, Tel Aviv, Israel; 3Nephrology, Beilinson Hospital, Tel Aviv, Israel

    IntroductionInvolvement of bariatric operations in the peri-transplant setting could be at different stages – prospective living organ donor (group 1), prospective organ recipient (2), patients…
  • 2016 American Transplant Congress

    Bile Acid Signaling Affects Metabolism and Prolongs Allograft Survival in Obese Recipients.

    M. Quante, A. ElKhal, M. Seyda, J. Schuitenmaker, H. Uehara, S. Tullius.

    Division of Transplant Surgery & Transplant Surgery Research Laboratory, Brigham and Women's Hospital / Harvard Medical School, Boston, MA.

    Although obesity has been linked to impaired transplant outcomes, underlying mechanisms and consequences of obesity on alloimmunity are only poorly understood.Allogenic skin transplantations were performed…
  • 2016 American Transplant Congress

    A Genome Wide Association Study of New Onset Diabetes After Transplant in Kidney Transplantation.

    A. Giri,1 M. Sanders,2 D. Velez Edwards,1 T. Ikizler,3 D. Roden,3 K. Birdwell.3

    1Epidemiology, Vanderbilt University Medical Center, Nashville, TN; 2Medicine, University of Iowa, Iowa City, IA; 3Medicine, Vanderbilt University Medical Center, Nashville, TN.

    Purpose: New-onset diabetes after transplantation (NODAT) is associated increased mortality. Using a DNA biobank linked to electronic medical records (EMR) at Vanderbilt University (BioVU), we…
  • 2016 American Transplant Congress

    Pre-Existing Diabetes Mellitus Type 2 and Insufficiently Controlled Post-Transplant HbA1c in Kidney Transplantation.

    F. Halleck, D. Khadzhynov, L. Lehner, E. Schrezenmeier, M. Duerr, A. Kleinsteuber, K. Budde, O. Staeck.

    Nephrology, Charité University, Berlin, Germany.

    Background Limited data have been reported on the outcomes of kidney transplant recipients (KTR) with pre-existing diabetes mellitus type 2 (preDM) at time of transplantation…
  • 2016 American Transplant Congress

    Variation in Co-Medication Use According to Kidney Transplant Immunosuppressive Regimen: Application of Integrated Registry and Pharmacy Claims Data.

    K. Lentine,1 A. Naik,2 M. Schnitzler,1 D. Axelrod,3 J. Chen,1 D. Brennan,4 D. Segev,5 B. Kasiske,6 H. Randall,1 V. Dharnidharka.4

    1Saint Louis Univ, St. Louis; 2Univ Michigan, Detroit; 3Dartmouth Univ, Hanover; 4Washington Univ, St. Louis; 5Johns Hopkins Univ, Baltimore; 6Univ Minnesota, Minneapolis.

    Background: While modern immunosuppressive therapies (ISx) have substantially reduced acute rejection, ISx medications have many side effects, and transplant recipients must take an array of…
  • 2016 American Transplant Congress

    Evolution of Body Composition and Associations to Glucose Metabolism During the First Year After Kidney Transplantation.

    M. von Düring,1 A. Hartmann,1,2 J. Bollerslev,2,4 A. Åsberg,1,3 K. Godang,4 I. Eide,1 D. Dahle,1 T. Jenssen.1,5

    1Department of Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway; 2Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway; 3School of Pharmacy, University of Oslo, Oslo, Norway; 4Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway; 5Metabolic and Renal Research Group, University of Tromsø, Tromsø, Norway.

    Background. The evolution and association between body composition and glucose haemostasis after kidney transplantation has not been elucidated.Methods. We investigated 150 consecutive patients without suspected…
  • 2016 American Transplant Congress

    Serum Bicarbonate and Long-Term Outcomes in Kidney Transplant Recipients.

    S. Park,1 E. Kang,1 M. Han,1 J. Park,1 S. Yang,2 S. Park,3 I. Jung,4 C. Lim,5 Y. Kim,1 Y. Kim,6 J. Lee.5

    1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; 2Kidney Research Institute, Seoul National University College of Medicine, Seoul, Korea; 3Department of Internal Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea; 4Department of Surgery, Seoul National University Boramae Medical Center, Seoul, Korea; 5Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; 6Department of Surgery, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea.

    Background: Metabolic acidosis indicated by low serum bicarbonate (TCO2) level has been known as a risk factor for mortality and progressive renal dysfunction in patients…
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